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Analysis of Effect of Eggshell Membrane Patching for Moderate-to-Large Traumatic Tympanic Membrane Perforation

View Article: PubMed Central - PubMed

ABSTRACT

Background and objectives: To evaluate the effect of eggshell membrane (ESM) patching for tympanic membrane (TM) perforation, and to investigate correlations between healing time and age, gender, patching time, perforation size, and perforation location.

Subjects and methods: One hundred and seventy-five patients diagnosed with traumatic TM perforation at the Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, between January 2008 and October 2013. Patients were divided into two groups, according to perforation edge approximation or ESM patching treatment. Healing time was compared between the group that received perforation edge approximation and the group that received ESM patching. Perforation grade, age, onset, and location were also compared between the two groups.

Results: ESM patching significantly improved healing time compared to spontaneous healing, especially in patients with moderate or large traumatic TM perforations (≥grade II). However, patient age, gender, perforation location, and especially timing of procedure, did not significantly affect healing time.

Conclusions: ESM patching can be a good treatment choice to promote tympanic membrane healing in large traumatic TM perforations.

No MeSH data available.


Healing time in the ESM patching group and the approximation group according to TM perforation grade. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007*). *statistically significant. ESM: eggshell membrane, TM: tympanic membrane.
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Figure 2: Healing time in the ESM patching group and the approximation group according to TM perforation grade. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007*). *statistically significant. ESM: eggshell membrane, TM: tympanic membrane.

Mentions: Healing time analysis between the ESM patch group and the approximation group included 103 patients with small traumatic TM perforation (grade I) and 72 patients with moderate-to-large traumatic TM perforation (≥grade II). Characteristics of the two groups are compared in Table 1. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007) (Fig. 2).


Analysis of Effect of Eggshell Membrane Patching for Moderate-to-Large Traumatic Tympanic Membrane Perforation
Healing time in the ESM patching group and the approximation group according to TM perforation grade. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007*). *statistically significant. ESM: eggshell membrane, TM: tympanic membrane.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5392004&req=5

Figure 2: Healing time in the ESM patching group and the approximation group according to TM perforation grade. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007*). *statistically significant. ESM: eggshell membrane, TM: tympanic membrane.
Mentions: Healing time analysis between the ESM patch group and the approximation group included 103 patients with small traumatic TM perforation (grade I) and 72 patients with moderate-to-large traumatic TM perforation (≥grade II). Characteristics of the two groups are compared in Table 1. The mean perforation closure times were 37.3±24.5 in the approximation group and 36.4±26.4 days in the ESM patch group in patients with small traumatic TM perforation. Complete closure time was not statistically different between the 2 groups (p=0.205). However, in patients with moderate-to-large traumatic TM perforation, the mean perforation closure times was 110.4±127.4 in the approximation group and 77.4±78.6 days in the ESM patch group. Healing time was significantly shorter in the ESM patch group than in the approximation group in patients with moderate-to-large traumatic TM perforation (p=0.007) (Fig. 2).

View Article: PubMed Central - PubMed

ABSTRACT

Background and objectives: To evaluate the effect of eggshell membrane (ESM) patching for tympanic membrane (TM) perforation, and to investigate correlations between healing time and age, gender, patching time, perforation size, and perforation location.

Subjects and methods: One hundred and seventy-five patients diagnosed with traumatic TM perforation at the Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, between January 2008 and October 2013. Patients were divided into two groups, according to perforation edge approximation or ESM patching treatment. Healing time was compared between the group that received perforation edge approximation and the group that received ESM patching. Perforation grade, age, onset, and location were also compared between the two groups.

Results: ESM patching significantly improved healing time compared to spontaneous healing, especially in patients with moderate or large traumatic TM perforations (≥grade II). However, patient age, gender, perforation location, and especially timing of procedure, did not significantly affect healing time.

Conclusions: ESM patching can be a good treatment choice to promote tympanic membrane healing in large traumatic TM perforations.

No MeSH data available.