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Ethnicity and anticoagulation management of hospitalized patients with atrial fibrillation in northwest China

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ABSTRACT

The therapeutic management and health challenges caused by atrial fibrillation (AF) differ between different groups. The purpose of this study was to investigate the clinical features of patients hospitalized with AF and to explore the use of anticoagulation treatments in Han and Uygur patients in Xinjiang, northwest China. Data were collected from a retrospective descriptive study involving patients hospitalized at 13 hospitals in Xinjiang, China from Jul 1, 2014 to Jun 31, 2015. Anticoagulation management was measured according to guideline-recommended risk scores. A total of 4,181 patients with AF were included (mean age 69.5 ± 11.7 years, 41.4% females; 71.5% Han, 28.5% Uygur). The prevalence of AF in Uygur individuals may occur earlier than in Han individuals (mean age 64.9 vs 71.3, P < 0.001). Most of the hospitalized patients with AF had a high risk of stroke (CHA2DS2-VASc score ≥2; 80.6% Han vs 73.7% Uygur, P < 0.05); this risk was especially high in elderly patients. In AF patients, the application of anticoagulants according to the guidelines is far from expected, and the underutilization of anticoagulants exists in both ethnic groups.

No MeSH data available.


Age distribution of different ethnicity patients with AF.
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f1: Age distribution of different ethnicity patients with AF.

Mentions: A total of 4181 cases with AF were identified at 13 sites from Jul 1, 2014 to Jun 31, 2015. 2990 (71.5%) patients were Han and 1191 (28.5%) were Uygur, as shown in Table 1. Compared with Han participants, Uygur participants were younger; had higher body mass index (BMI), and a higher prevalence of HF with reduced ejection fraction and chronic obstructive pulmonary disease (COPD). Han participants presented with higher incidents of hypertension, diabetes mellitus (DM) and stroke. The distribution of AF prevalence showed that the prevalence increased with age; the prevalence of AF was greatest in Han individuals between 75~85 years old and Uygur individuals between 55~74 years old (Fig. 1).


Ethnicity and anticoagulation management of hospitalized patients with atrial fibrillation in northwest China
Age distribution of different ethnicity patients with AF.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5385550&req=5

f1: Age distribution of different ethnicity patients with AF.
Mentions: A total of 4181 cases with AF were identified at 13 sites from Jul 1, 2014 to Jun 31, 2015. 2990 (71.5%) patients were Han and 1191 (28.5%) were Uygur, as shown in Table 1. Compared with Han participants, Uygur participants were younger; had higher body mass index (BMI), and a higher prevalence of HF with reduced ejection fraction and chronic obstructive pulmonary disease (COPD). Han participants presented with higher incidents of hypertension, diabetes mellitus (DM) and stroke. The distribution of AF prevalence showed that the prevalence increased with age; the prevalence of AF was greatest in Han individuals between 75~85 years old and Uygur individuals between 55~74 years old (Fig. 1).

View Article: PubMed Central - PubMed

ABSTRACT

The therapeutic management and health challenges caused by atrial fibrillation (AF) differ between different groups. The purpose of this study was to investigate the clinical features of patients hospitalized with AF and to explore the use of anticoagulation treatments in Han and Uygur patients in Xinjiang, northwest China. Data were collected from a retrospective descriptive study involving patients hospitalized at 13 hospitals in Xinjiang, China from Jul 1, 2014 to Jun 31, 2015. Anticoagulation management was measured according to guideline-recommended risk scores. A total of 4,181 patients with AF were included (mean age 69.5 ± 11.7 years, 41.4% females; 71.5% Han, 28.5% Uygur). The prevalence of AF in Uygur individuals may occur earlier than in Han individuals (mean age 64.9 vs 71.3, P < 0.001). Most of the hospitalized patients with AF had a high risk of stroke (CHA2DS2-VASc score ≥2; 80.6% Han vs 73.7% Uygur, P < 0.05); this risk was especially high in elderly patients. In AF patients, the application of anticoagulants according to the guidelines is far from expected, and the underutilization of anticoagulants exists in both ethnic groups.

No MeSH data available.