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Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia

View Article: PubMed Central - PubMed

ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3 months after the surgeries and were compared using the Mann-Whitney test or Student’s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean ± SD: −0.02 ± 0.07 and −0.04 ± 0.22 respectively, in logMAR) and after SMILE (−0.01 ± 0.06 and −0.04 ± 0.04 respectively). However, greater vertical coma aberration was found after SMILE (p = 0.036). Preoperative SE was correlated to induced horizontal coma (r = −0.608, p = 0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r = −0.459, p = 0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients’ vision under certain lighting conditions and needs further investigation.

No MeSH data available.


Related in: MedlinePlus

Scatter plots for preoperative spherical equivalent (SE) and changes in Zernike coefficients measured 3 months after wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE). Regression lines and corresponding r2 and p values were reported for both groups. Left: SE and vertical coma with SMILE. Middle: SE and horizontal coma with wavefront-guided femtosecond LASIK. Right: Preoperative SE and induced spherical aberration
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Fig6: Scatter plots for preoperative spherical equivalent (SE) and changes in Zernike coefficients measured 3 months after wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE). Regression lines and corresponding r2 and p values were reported for both groups. Left: SE and vertical coma with SMILE. Middle: SE and horizontal coma with wavefront-guided femtosecond LASIK. Right: Preoperative SE and induced spherical aberration

Mentions: The left picture in Fig. 6 shows that there was a significant correlation between induced vertical coma and preoperative SE in the SMILE group but not in the WFG FS-LASIK group; there was also a significant difference in the regression slopes between the two groups (Z = 2.123, p = 0.038). Conversely, the middle one reveals a significant correlation between induced horizontal coma and preoperative SE in the WFG FS-LASIK group but not in the SMILE group; the regression slope, however, was not significantly different between the two groups (Z = 0.044, p = 0.965).Fig. 6


Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia
Scatter plots for preoperative spherical equivalent (SE) and changes in Zernike coefficients measured 3 months after wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE). Regression lines and corresponding r2 and p values were reported for both groups. Left: SE and vertical coma with SMILE. Middle: SE and horizontal coma with wavefront-guided femtosecond LASIK. Right: Preoperative SE and induced spherical aberration
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5384151&req=5

Fig6: Scatter plots for preoperative spherical equivalent (SE) and changes in Zernike coefficients measured 3 months after wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE). Regression lines and corresponding r2 and p values were reported for both groups. Left: SE and vertical coma with SMILE. Middle: SE and horizontal coma with wavefront-guided femtosecond LASIK. Right: Preoperative SE and induced spherical aberration
Mentions: The left picture in Fig. 6 shows that there was a significant correlation between induced vertical coma and preoperative SE in the SMILE group but not in the WFG FS-LASIK group; there was also a significant difference in the regression slopes between the two groups (Z = 2.123, p = 0.038). Conversely, the middle one reveals a significant correlation between induced horizontal coma and preoperative SE in the WFG FS-LASIK group but not in the SMILE group; the regression slope, however, was not significantly different between the two groups (Z = 0.044, p = 0.965).Fig. 6

View Article: PubMed Central - PubMed

ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3 months after the surgeries and were compared using the Mann-Whitney test or Student’s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean ± SD: −0.02 ± 0.07 and −0.04 ± 0.22 respectively, in logMAR) and after SMILE (−0.01 ± 0.06 and −0.04 ± 0.04 respectively). However, greater vertical coma aberration was found after SMILE (p = 0.036). Preoperative SE was correlated to induced horizontal coma (r = −0.608, p = 0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r = −0.459, p = 0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients’ vision under certain lighting conditions and needs further investigation.

No MeSH data available.


Related in: MedlinePlus