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Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia

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ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3 months after the surgeries and were compared using the Mann-Whitney test or Student’s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean ± SD: −0.02 ± 0.07 and −0.04 ± 0.22 respectively, in logMAR) and after SMILE (−0.01 ± 0.06 and −0.04 ± 0.04 respectively). However, greater vertical coma aberration was found after SMILE (p = 0.036). Preoperative SE was correlated to induced horizontal coma (r = −0.608, p = 0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r = −0.459, p = 0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients’ vision under certain lighting conditions and needs further investigation.

No MeSH data available.


Root mean square (RMS) of total HOA and individual Zernike coefficients in wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE) groups 3 months after surgery. Error bars indicate standard errors and asterisks indicate p values <0.05
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Fig5: Root mean square (RMS) of total HOA and individual Zernike coefficients in wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE) groups 3 months after surgery. Error bars indicate standard errors and asterisks indicate p values <0.05

Mentions: Figure 5 shows that the values of coma, spherical aberration, and total HOA increased significantly in both groups 3 months after surgery as compared to the preoperative data. Table 2 shows significantly higher vertical coma values following SMILE surgery versus wavefront-guided femtosecond LASIK (Z = −2.102, p = 0.036); however, no significant difference was found in horizontal coma aberration. The generalized estimating equation (GEE) analysis also revealed a significant difference in vertical coma between the two groups (W = 4.901, p = 0.027). The trefoil was a little higher following WFG FS-LASIK in comparison to SMILE, but the difference was not significant.Fig. 5


Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia
Root mean square (RMS) of total HOA and individual Zernike coefficients in wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE) groups 3 months after surgery. Error bars indicate standard errors and asterisks indicate p values <0.05
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5384151&req=5

Fig5: Root mean square (RMS) of total HOA and individual Zernike coefficients in wavefront-guided femtosecond LASIK (WFG FS-LASIK) and small incision lenticule extraction (SMILE) groups 3 months after surgery. Error bars indicate standard errors and asterisks indicate p values <0.05
Mentions: Figure 5 shows that the values of coma, spherical aberration, and total HOA increased significantly in both groups 3 months after surgery as compared to the preoperative data. Table 2 shows significantly higher vertical coma values following SMILE surgery versus wavefront-guided femtosecond LASIK (Z = −2.102, p = 0.036); however, no significant difference was found in horizontal coma aberration. The generalized estimating equation (GEE) analysis also revealed a significant difference in vertical coma between the two groups (W = 4.901, p = 0.027). The trefoil was a little higher following WFG FS-LASIK in comparison to SMILE, but the difference was not significant.Fig. 5

View Article: PubMed Central - PubMed

ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3&nbsp;months after the surgeries and were compared using the Mann-Whitney test or Student&rsquo;s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean&nbsp;&plusmn;&nbsp;SD: &minus;0.02&nbsp;&plusmn;&nbsp;0.07 and &minus;0.04&nbsp;&plusmn;&nbsp;0.22 respectively, in logMAR) and after SMILE (&minus;0.01&nbsp;&plusmn;&nbsp;0.06 and &minus;0.04&nbsp;&plusmn;&nbsp;0.04 respectively). However, greater vertical coma aberration was found after SMILE (p&nbsp;=&nbsp;0.036). Preoperative SE was correlated to induced horizontal coma (r&nbsp;=&nbsp;&minus;0.608, p&nbsp;=&nbsp;0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r&nbsp;=&nbsp;&minus;0.459, p&nbsp;=&nbsp;0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients&rsquo; vision under certain lighting conditions and needs further investigation.

No MeSH data available.