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Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia

View Article: PubMed Central - PubMed

ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3 months after the surgeries and were compared using the Mann-Whitney test or Student’s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean ± SD: −0.02 ± 0.07 and −0.04 ± 0.22 respectively, in logMAR) and after SMILE (−0.01 ± 0.06 and −0.04 ± 0.04 respectively). However, greater vertical coma aberration was found after SMILE (p = 0.036). Preoperative SE was correlated to induced horizontal coma (r = −0.608, p = 0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r = −0.459, p = 0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients’ vision under certain lighting conditions and needs further investigation.

No MeSH data available.


Related in: MedlinePlus

Relationship between targeted and achieved absolute spherical equivalent (SE) 3 months after surgery. The area above the diagonal dotted line indicates overcorrection and the area below the line indicates undercorrection. Regression lines and corresponding R2 was reported for both groups
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Fig3: Relationship between targeted and achieved absolute spherical equivalent (SE) 3 months after surgery. The area above the diagonal dotted line indicates overcorrection and the area below the line indicates undercorrection. Regression lines and corresponding R2 was reported for both groups

Mentions: Table 2 shows that there was no significant difference in the SE between the two groups 3 months after surgery. Figure 3 shows that the SE was corrected to the targeted level after both types of surgery for all eyes. There was no significant difference (Z = −0.476, p = −0.631) in the percentage of eyes achieving emmetropia based on a threshold of ±0.50 D between the two groups (Fig. 4).Fig. 3


Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia
Relationship between targeted and achieved absolute spherical equivalent (SE) 3 months after surgery. The area above the diagonal dotted line indicates overcorrection and the area below the line indicates undercorrection. Regression lines and corresponding R2 was reported for both groups
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5384151&req=5

Fig3: Relationship between targeted and achieved absolute spherical equivalent (SE) 3 months after surgery. The area above the diagonal dotted line indicates overcorrection and the area below the line indicates undercorrection. Regression lines and corresponding R2 was reported for both groups
Mentions: Table 2 shows that there was no significant difference in the SE between the two groups 3 months after surgery. Figure 3 shows that the SE was corrected to the targeted level after both types of surgery for all eyes. There was no significant difference (Z = −0.476, p = −0.631) in the percentage of eyes achieving emmetropia based on a threshold of ±0.50 D between the two groups (Fig. 4).Fig. 3

View Article: PubMed Central - PubMed

ABSTRACT

Background: To compare changes in higher-order aberrations (HOAs) following small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG FS-LASIK), and to investigate correlations between preoperative spherical equivalence (SE) and components of HOAs affecting visual quality.

Methods: Sixty-five myopic eyes from 38 patients were enrolled in the study retrospectively, either having undergone SMILE or WFG FS-LASIK. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error, and individual Zernike coefficients of 3rd- to 6th-order HOAs were measured before and 3 months after the surgeries and were compared using the Mann-Whitney test or Student’s t-test. Additional generalized estimating equation analyses (GEE) were used to control for within-subject biases in individual Zernike coefficients between the right and left eyes of the same patients.

Results: There was no significant difference in UDVA or CDVA after WFG FS-LASIK (Mean ± SD: −0.02 ± 0.07 and −0.04 ± 0.22 respectively, in logMAR) and after SMILE (−0.01 ± 0.06 and −0.04 ± 0.04 respectively). However, greater vertical coma aberration was found after SMILE (p = 0.036). Preoperative SE was correlated to induced horizontal coma (r = −0.608, p = 0.001) in WFG FS-LASIK, and correlated to induced vertical coma (r = −0.459, p = 0.003) in SMILE.

Conclusions: Both SMILE and WFG FS-LASIK can achieve planned visual outcomes in correcting myopia and myopic astigmatism. However, higher vertical coma was shown in SMILE than WFG FS-LASIK which might be a potentially impact factor for patients’ vision under certain lighting conditions and needs further investigation.

No MeSH data available.


Related in: MedlinePlus