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Contrast Sensitivity in Microtropic and Anisometropic Eyes of Successfully Treated Amblyopes

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: To assess and compare contrast sensitivity function in the previously amblyopic and non-amblyopic “normal” eyes of patients with microtropia and anisometropia who achieved 20/20 visual acuity after occlusion therapy.

Materials and methods:: Contrast sensitivity was tested monocularly on both eyes of 34 successfully treated microtropic and 15 anisometropic subjects (visual acuity 20/20 in both eyes). Contrast sensitivity function was evaluated by CSV-1000E and age-matched nomograms were used (spatial frequencies of 3, 6, 12, and 18 cycles per degree [cpd]) for comparison.

Results:: The mean age of subjects was 11.2±1.3 years in the microtropic group, 9.8±1.7 years in the anisometropic group (7-12 years); the mean follow-up time was 16.4±3.2 months (12 to 92) in the microtropic group and 27.7±1.8 months (12-84) in the anisometropic group. Statistical comparison of the microtropic amblyopic eyes versus non-microtropic eyes showed significant differences at spatial frequencies of 3, 12 and 18 cpd (3 cpd, t=2.8, p=0.007; 6 cpd, t=1.1 p=0.261; 12 cpd, t=2.2, p=0.033; 18 cpd, t=2.2, p=0.030). When anisometropic eyes were compared with non-anisometropic eyes, there was a significant difference only at 12 cpd (t=2.1 p=0.049). The comparison of non-amblyopic eyes versus age-matched nomograms revealed no differences at any of the spatial frequencies (p>0.05 for all).

Conclusion:: Contrast sensitivity was decreased in patients with amblyopia, especially in the microtropic group. The assessment of contrast sensitivity function may serve as a new parameter for termination of occlusion therapy.

No MeSH data available.


Mean contrast sensitivity function values of the anisometropic eyes (dotted line) and microtropic eyes (solid line)
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f6: Mean contrast sensitivity function values of the anisometropic eyes (dotted line) and microtropic eyes (solid line)


Contrast Sensitivity in Microtropic and Anisometropic Eyes of Successfully Treated Amblyopes
Mean contrast sensitivity function values of the anisometropic eyes (dotted line) and microtropic eyes (solid line)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5384123&req=5

f6: Mean contrast sensitivity function values of the anisometropic eyes (dotted line) and microtropic eyes (solid line)

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: To assess and compare contrast sensitivity function in the previously amblyopic and non-amblyopic “normal” eyes of patients with microtropia and anisometropia who achieved 20/20 visual acuity after occlusion therapy.

Materials and methods:: Contrast sensitivity was tested monocularly on both eyes of 34 successfully treated microtropic and 15 anisometropic subjects (visual acuity 20/20 in both eyes). Contrast sensitivity function was evaluated by CSV-1000E and age-matched nomograms were used (spatial frequencies of 3, 6, 12, and 18 cycles per degree [cpd]) for comparison.

Results:: The mean age of subjects was 11.2±1.3 years in the microtropic group, 9.8±1.7 years in the anisometropic group (7-12 years); the mean follow-up time was 16.4±3.2 months (12 to 92) in the microtropic group and 27.7±1.8 months (12-84) in the anisometropic group. Statistical comparison of the microtropic amblyopic eyes versus non-microtropic eyes showed significant differences at spatial frequencies of 3, 12 and 18 cpd (3 cpd, t=2.8, p=0.007; 6 cpd, t=1.1 p=0.261; 12 cpd, t=2.2, p=0.033; 18 cpd, t=2.2, p=0.030). When anisometropic eyes were compared with non-anisometropic eyes, there was a significant difference only at 12 cpd (t=2.1 p=0.049). The comparison of non-amblyopic eyes versus age-matched nomograms revealed no differences at any of the spatial frequencies (p>0.05 for all).

Conclusion:: Contrast sensitivity was decreased in patients with amblyopia, especially in the microtropic group. The assessment of contrast sensitivity function may serve as a new parameter for termination of occlusion therapy.

No MeSH data available.