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Comparison of Outcomes in Patients Who Underwent Deep Anterior Lamellar Keratoplasty and Those Converted to Penetrating Keratoplasty

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ABSTRACT

Objectives:: To compare clinical outcomes of cases who underwent deep anterior lamellar keratoplasty (DALK) and cases who were converted to penetrating keratoplasty (PKP) from DALK surgery.

Materials and methods:: The records of 54 patients for whom DALK surgery was planned and were operated for different diagnoses between March 2013 and June 2015 were retrospectively analyzed. Patients were divided into two groups: group 1 (PKP group) consisted of 23 cases who were converted to PKP due to Descemet’s membrane perforation at any stage of surgery; group 2 (DALK group) consisted of 31 patients whose surgery could be completed as DALK. Preoperative and postoperative follow-up results were evaluated in each group.

Results:: Corrected distance visual acuity (CDVA) increased in the postoperative period according to baseline in both groups. However, there was no statistically significant difference in the rates of CDVA increase between the groups (p=0.142). The mean astigmatism measured by corneal topography at final examination was 5.8±2.3 diopters in group 1 and 5.4±1.8 diopters in group 2. The difference between groups was not statistically significant (p=0.430). The groups were not statistically different regarding postoperative pachymetry (p=0.453). The grafts in all 54 patients (100%) were clear at final postoperative examination. There were no statistically significant differences between the groups in terms of postoperative complications.

Conclusion:: Similar clinical outcomes were obtained in our study for patients who underwent DALK and those whose procedure was converted from DALK to PKP.

No MeSH data available.


Changes in corrected distance visual acuity in the study groupsPreop: Preoperative, Postop: Postoperative, CDVA: Corrected distance visual acuity, PKP: Penetrating keratoplasty, DALK: Deep anterior lamellar keratoplasty
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f1: Changes in corrected distance visual acuity in the study groupsPreop: Preoperative, Postop: Postoperative, CDVA: Corrected distance visual acuity, PKP: Penetrating keratoplasty, DALK: Deep anterior lamellar keratoplasty

Mentions: CDVA had significantly improved compared to baseline at postoperative 1 day, 1 month, and at final examination in both groups (p<0.001 for all). However, there was no statistically significant difference in the rates of CDVA increase between the groups (p=0.142, two-way repeated measures ANOVA). Changes in CDVA are presented in Figure 1. IOP values measured preoperatively and postoperatively showed no significant differences in either group, and there was no significant difference between the groups (p=0.456). Mean astigmatism value obtained by corneal topography at final examination was 5.8±2.3 diopters in the PKP group and 5.4±1.8 diopters in the DALK group. There was no significant difference between the groups (p=0.430). Mean central corneal thickness obtained by corneal topography at final examination was 535±35.2 μm in the PKP group and 532±40.1 μm in the DALK group. The difference between the groups was not statistically significant (p=0.453).


Comparison of Outcomes in Patients Who Underwent Deep Anterior Lamellar Keratoplasty and Those Converted to Penetrating Keratoplasty
Changes in corrected distance visual acuity in the study groupsPreop: Preoperative, Postop: Postoperative, CDVA: Corrected distance visual acuity, PKP: Penetrating keratoplasty, DALK: Deep anterior lamellar keratoplasty
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5384121&req=5

f1: Changes in corrected distance visual acuity in the study groupsPreop: Preoperative, Postop: Postoperative, CDVA: Corrected distance visual acuity, PKP: Penetrating keratoplasty, DALK: Deep anterior lamellar keratoplasty
Mentions: CDVA had significantly improved compared to baseline at postoperative 1 day, 1 month, and at final examination in both groups (p<0.001 for all). However, there was no statistically significant difference in the rates of CDVA increase between the groups (p=0.142, two-way repeated measures ANOVA). Changes in CDVA are presented in Figure 1. IOP values measured preoperatively and postoperatively showed no significant differences in either group, and there was no significant difference between the groups (p=0.456). Mean astigmatism value obtained by corneal topography at final examination was 5.8±2.3 diopters in the PKP group and 5.4±1.8 diopters in the DALK group. There was no significant difference between the groups (p=0.430). Mean central corneal thickness obtained by corneal topography at final examination was 535±35.2 μm in the PKP group and 532±40.1 μm in the DALK group. The difference between the groups was not statistically significant (p=0.453).

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: To compare clinical outcomes of cases who underwent deep anterior lamellar keratoplasty (DALK) and cases who were converted to penetrating keratoplasty (PKP) from DALK surgery.

Materials and methods:: The records of 54 patients for whom DALK surgery was planned and were operated for different diagnoses between March 2013 and June 2015 were retrospectively analyzed. Patients were divided into two groups: group 1 (PKP group) consisted of 23 cases who were converted to PKP due to Descemet&rsquo;s membrane perforation at any stage of surgery; group 2 (DALK group) consisted of 31 patients whose surgery could be completed as DALK. Preoperative and postoperative follow-up results were evaluated in each group.

Results:: Corrected distance visual acuity (CDVA) increased in the postoperative period according to baseline in both groups. However, there was no statistically significant difference in the rates of CDVA increase between the groups (p=0.142). The mean astigmatism measured by corneal topography at final examination was 5.8&plusmn;2.3 diopters in group 1 and 5.4&plusmn;1.8 diopters in group 2. The difference between groups was not statistically significant (p=0.430). The groups were not statistically different regarding postoperative pachymetry (p=0.453). The grafts in all 54 patients (100%) were clear at final postoperative examination. There were no statistically significant differences between the groups in terms of postoperative complications.

Conclusion:: Similar clinical outcomes were obtained in our study for patients who underwent DALK and those whose procedure was converted from DALK to PKP.

No MeSH data available.