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Age-related normative values for handgrip strength and grip strength ’ s usefulness as a predictor of mortality and both cognitive and physical decline in older adults in northwest Russia

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: This paper sought to provide normative values for grip strength among older adults across different age groups in northwest Russia and to investigate their predictive value for adverse events.

Methods:: A population-based prospective cohort study of 611 community-dwelling individuals 65+. Grip strength was measured using the standard protocol applied in the Groningen Elderly Tests. The cut-off thresholds for grip strength were defined separately for men and women of different ages using a weighted polynomial regression. A Cox regression analysis, the c-statistic, a risk reclassification analysis, and bootstrapping techniques were used to analyze the data. The outcomes were the 5-year mortality rate, the loss of autonomy and mental decline.

Results:: We determined the age-related reference intervals of grip strength for older adults. The 5th and 10th percentiles of grip strength were associated with a higher risk for malnutrition, low autonomy, physical and mental functioning and 5-year mortality. The 5th percentile of grip strength was associated with a decline in autonomy.

Conclusions:: This study presents age- and sex-specific reference values for grip strength in the 65+ Russian population derived from a prospective cohort study. The norms can be used in clinical practice to identify patients at increased risk for adverse outcomes.

No MeSH data available.


Related in: MedlinePlus

Age-related declines in average grip strength.
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Figure 1: Age-related declines in average grip strength.

Mentions: To create age-related grip strength reference intervals for healthy older people, we chose participants from the first (84 men and 185 women) and second (37 men and 87 women) assessments with MMSE scores >=23, BI scores >95 and SPPB scores >=8. The grip strength data taken at the second and first assessments were mixed to increase the amount of older people for the calculation of the age-related reference interval. The results are presented in Figures 1 and 2.


Age-related normative values for handgrip strength and grip strength ’ s usefulness as a predictor of mortality and both cognitive and physical decline in older adults in northwest Russia
Age-related declines in average grip strength.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5383770&req=5

Figure 1: Age-related declines in average grip strength.
Mentions: To create age-related grip strength reference intervals for healthy older people, we chose participants from the first (84 men and 185 women) and second (37 men and 87 women) assessments with MMSE scores >=23, BI scores >95 and SPPB scores >=8. The grip strength data taken at the second and first assessments were mixed to increase the amount of older people for the calculation of the age-related reference interval. The results are presented in Figures 1 and 2.

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: This paper sought to provide normative values for grip strength among older adults across different age groups in northwest Russia and to investigate their predictive value for adverse events.

Methods:: A population-based prospective cohort study of 611 community-dwelling individuals 65+. Grip strength was measured using the standard protocol applied in the Groningen Elderly Tests. The cut-off thresholds for grip strength were defined separately for men and women of different ages using a weighted polynomial regression. A Cox regression analysis, the c-statistic, a risk reclassification analysis, and bootstrapping techniques were used to analyze the data. The outcomes were the 5-year mortality rate, the loss of autonomy and mental decline.

Results:: We determined the age-related reference intervals of grip strength for older adults. The 5th and 10th percentiles of grip strength were associated with a higher risk for malnutrition, low autonomy, physical and mental functioning and 5-year mortality. The 5th percentile of grip strength was associated with a decline in autonomy.

Conclusions:: This study presents age- and sex-specific reference values for grip strength in the 65+ Russian population derived from a prospective cohort study. The norms can be used in clinical practice to identify patients at increased risk for adverse outcomes.

No MeSH data available.


Related in: MedlinePlus