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Efficacy of Punch Reduction Prior to Cryotherapy in Patients with Viral Warts: A Case-Control Study in a Single Tertiary Center

View Article: PubMed Central - PubMed

ABSTRACT

Background: Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment.

Objective: To evaluate the efficacy and safety of punch biopsy for cutaneous warts.

Methods: Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 15 were matched with cryotherapy-only controls in terms of size and location of the wart. We compared the number and cost of treatments between the two groups.

Results: Eleven of the total 39 patients were treated with cryotherapy in addition to punch biopsy and the average number of treatments was 4.1±3.3 (mean±standard deviation). In a case-control study, the ratio value of cost was 2.9±3.6 in the experimental group and was 5.9±4.1 in controls (p<0.05).

Conclusion: Punch biopsies can decrease the number and cost of treatment by reducing the size of warts and inducing local inflammation to accelerate resolution. Therefore, punch reduction should be considered as a viable measure to treat warts.

No MeSH data available.


Related in: MedlinePlus

Clinical image of the matched case (A, B, C, D) and control (A', B', C', D') groups (dotted circles: viral wart).
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Figure 3: Clinical image of the matched case (A, B, C, D) and control (A', B', C', D') groups (dotted circles: viral wart).

Mentions: Among 39 patients, 15 were matched with controls. The case and control groups were similar in size and location of the warts (Fig. 3). The average age of the case group is 27.5±19.6 years (range, 2~66 years) and the sex ratio was 1.1. The average age of the control group was 30.3±17.9 years (range, 9~60 years) and the sex ratio was 2.75. There is no statistically significant difference in age and sex distribution between case and control group (Table 2). The average number of all procedures in the case group is 2.3±3.6, which also equals the number of visits to clinic. Eleven of the 15 patients in the case group did not need further treatment after punch biopsy. In the control group, the average number of procedures is 5.9±4.1. The number of treatments in the case group is less than that in the control group (p<0.05). The cost of a punch biopsy is 1.6 times that of a cryotherapy (The cost of cryotherapy is $22.30, that of a punch biopsy is $35.68, and the ratio of the former and latter is 1:1.6.). The ratio value of average total cost is 2.9±3.6 in the case group and 5.9±4.1 in the control group (p<0.05; Table 2).


Efficacy of Punch Reduction Prior to Cryotherapy in Patients with Viral Warts: A Case-Control Study in a Single Tertiary Center
Clinical image of the matched case (A, B, C, D) and control (A', B', C', D') groups (dotted circles: viral wart).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5383746&req=5

Figure 3: Clinical image of the matched case (A, B, C, D) and control (A', B', C', D') groups (dotted circles: viral wart).
Mentions: Among 39 patients, 15 were matched with controls. The case and control groups were similar in size and location of the warts (Fig. 3). The average age of the case group is 27.5±19.6 years (range, 2~66 years) and the sex ratio was 1.1. The average age of the control group was 30.3±17.9 years (range, 9~60 years) and the sex ratio was 2.75. There is no statistically significant difference in age and sex distribution between case and control group (Table 2). The average number of all procedures in the case group is 2.3±3.6, which also equals the number of visits to clinic. Eleven of the 15 patients in the case group did not need further treatment after punch biopsy. In the control group, the average number of procedures is 5.9±4.1. The number of treatments in the case group is less than that in the control group (p<0.05). The cost of a punch biopsy is 1.6 times that of a cryotherapy (The cost of cryotherapy is $22.30, that of a punch biopsy is $35.68, and the ratio of the former and latter is 1:1.6.). The ratio value of average total cost is 2.9±3.6 in the case group and 5.9±4.1 in the control group (p<0.05; Table 2).

View Article: PubMed Central - PubMed

ABSTRACT

Background: Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment.

Objective: To evaluate the efficacy and safety of punch biopsy for cutaneous warts.

Methods: Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 15 were matched with cryotherapy-only controls in terms of size and location of the wart. We compared the number and cost of treatments between the two groups.

Results: Eleven of the total 39 patients were treated with cryotherapy in addition to punch biopsy and the average number of treatments was 4.1&plusmn;3.3 (mean&plusmn;standard deviation). In a case-control study, the ratio value of cost was 2.9&plusmn;3.6 in the experimental group and was 5.9&plusmn;4.1 in controls (p&lt;0.05).

Conclusion: Punch biopsies can decrease the number and cost of treatment by reducing the size of warts and inducing local inflammation to accelerate resolution. Therefore, punch reduction should be considered as a viable measure to treat warts.

No MeSH data available.


Related in: MedlinePlus