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Multichannel perimetric alterations in systemic lupus erythematosus treated with hydroxychloroquine

View Article: PubMed Central - PubMed

ABSTRACT

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease of unknown etiology with many clinical manifestations.

We report the first case of SLE in which visual alterations were evaluated with multichannel perimetry.

Some achromatic and color vision alterations may be present in SLE, especially when treated with hydroxychloroquine. The sensitivity losses detected in the chromatic channels in the central zone of the visual field were consistent with the results of the FM 100 Hue color test. Likewise, the multichannel perimetry detected sensitivity losses in the parafoveal area for both chromatic channels, especially for the blue-yellow.

No MeSH data available.


Related in: MedlinePlus

Results obtained with the multichannel perimetry. Top: maps of sensitivity (left), total deviation (center) and pattern deviation (right) for each eye and mechanism: achromatic (A), red-green (RG) and blue-yellow (BY). Bottom: statistical values for each mechanism: the medium defect (MD) and pattern standard deviation (PSD) are shown as well as the statistical significance (p-value) of the comparison with the normal healthy pattern.
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fig0010: Results obtained with the multichannel perimetry. Top: maps of sensitivity (left), total deviation (center) and pattern deviation (right) for each eye and mechanism: achromatic (A), red-green (RG) and blue-yellow (BY). Bottom: statistical values for each mechanism: the medium defect (MD) and pattern standard deviation (PSD) are shown as well as the statistical significance (p-value) of the comparison with the normal healthy pattern.

Mentions: The results of this test for RE and LE are displayed in Fig. 2.


Multichannel perimetric alterations in systemic lupus erythematosus treated with hydroxychloroquine
Results obtained with the multichannel perimetry. Top: maps of sensitivity (left), total deviation (center) and pattern deviation (right) for each eye and mechanism: achromatic (A), red-green (RG) and blue-yellow (BY). Bottom: statistical values for each mechanism: the medium defect (MD) and pattern standard deviation (PSD) are shown as well as the statistical significance (p-value) of the comparison with the normal healthy pattern.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5383461&req=5

fig0010: Results obtained with the multichannel perimetry. Top: maps of sensitivity (left), total deviation (center) and pattern deviation (right) for each eye and mechanism: achromatic (A), red-green (RG) and blue-yellow (BY). Bottom: statistical values for each mechanism: the medium defect (MD) and pattern standard deviation (PSD) are shown as well as the statistical significance (p-value) of the comparison with the normal healthy pattern.
Mentions: The results of this test for RE and LE are displayed in Fig. 2.

View Article: PubMed Central - PubMed

ABSTRACT

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease of unknown etiology with many clinical manifestations.

We report the first case of SLE in which visual alterations were evaluated with multichannel perimetry.

Some achromatic and color vision alterations may be present in SLE, especially when treated with hydroxychloroquine. The sensitivity losses detected in the chromatic channels in the central zone of the visual field were consistent with the results of the FM 100 Hue color test. Likewise, the multichannel perimetry detected sensitivity losses in the parafoveal area for both chromatic channels, especially for the blue-yellow.

No MeSH data available.


Related in: MedlinePlus