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Evaluation of the relationship between the biosecurity status, production parameters, herd characteristics and antimicrobial usage in farrow-to-finish pig production in four EU countries

View Article: PubMed Central - PubMed

ABSTRACT

Background: High antimicrobial usage and the threat of antimicrobial resistance highlighted the need for reduced antimicrobial usage in pig production. Prevention of disease however, is necessary to obtain a reduced need for antimicrobial treatment. This study aimed at assessing possible associations between the biosecurity level, antimicrobial usage and farm and production characteristics in order to advice on best practices for a low antimicrobial usage and maximum animal health and production.

Background: A cross-sectional study was conducted in 227 farrow-to-finish pig herds in Belgium, France, Germany and Sweden between December 2012 and December 2013. Associations between biosecurity status, antimicrobial usage, and production parameters were evaluated with multivariable general linear models, according to an assumed causal pathway.

Results: The results showed that higher antimicrobial usage in sows tended to be associated with higher antimicrobial usage from birth until slaughter (p = 0.06). The antimicrobial usage from birth until slaughter was positively associated with the number of pathogens vaccinated against (p < 0.01). A shorter farrowing rhythm (p < 0.01) and a younger weaning age (p = 0.06) tended to be also associated with a higher antimicrobial usage from birth until slaughter whereas a better external biosecurity (p < 0.01) was related with a lower antimicrobial usage from birth until slaughter.

Conclusion: Management practices such as weaning age and biosecurity measures may be important factors indirectly impacting on antimicrobial usage. We therefore promote a holistic approach when assessing the potential to reduce the need for antimicrobial treatments.

No MeSH data available.


Related in: MedlinePlus

Causal pathway associations for TI 200 days and TI Breeding. Causal pathway with statistically significant associations in the multivariable models for the TI 200 days and the TI Breeding associated with production, management or biosecurity variables. TI = treatment incidence (antimicrobial usage quantification), WSY = number of weaned piglets per sow per year. Black lines represent the result of a multivariable linear regression analysis based on data from 4 EU countries. The light gray line indicates 0.05 < p < 0.10. The p-values and β-values correspond to the multivariable model. All models were corrected for the country effect by placing country as a fixed variable in the model, hence the circle around the figure
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Fig1: Causal pathway associations for TI 200 days and TI Breeding. Causal pathway with statistically significant associations in the multivariable models for the TI 200 days and the TI Breeding associated with production, management or biosecurity variables. TI = treatment incidence (antimicrobial usage quantification), WSY = number of weaned piglets per sow per year. Black lines represent the result of a multivariable linear regression analysis based on data from 4 EU countries. The light gray line indicates 0.05 < p < 0.10. The p-values and β-values correspond to the multivariable model. All models were corrected for the country effect by placing country as a fixed variable in the model, hence the circle around the figure

Mentions: The country corrected univariable analysis resulted in retaining several variables related with the antimicrobial usage or with each other (Table 1). The associations that remained significant in the multivariable models are shown in the causal path in Fig. 1.Fig. 1


Evaluation of the relationship between the biosecurity status, production parameters, herd characteristics and antimicrobial usage in farrow-to-finish pig production in four EU countries
Causal pathway associations for TI 200 days and TI Breeding. Causal pathway with statistically significant associations in the multivariable models for the TI 200 days and the TI Breeding associated with production, management or biosecurity variables. TI = treatment incidence (antimicrobial usage quantification), WSY = number of weaned piglets per sow per year. Black lines represent the result of a multivariable linear regression analysis based on data from 4 EU countries. The light gray line indicates 0.05 < p < 0.10. The p-values and β-values correspond to the multivariable model. All models were corrected for the country effect by placing country as a fixed variable in the model, hence the circle around the figure
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5382489&req=5

Fig1: Causal pathway associations for TI 200 days and TI Breeding. Causal pathway with statistically significant associations in the multivariable models for the TI 200 days and the TI Breeding associated with production, management or biosecurity variables. TI = treatment incidence (antimicrobial usage quantification), WSY = number of weaned piglets per sow per year. Black lines represent the result of a multivariable linear regression analysis based on data from 4 EU countries. The light gray line indicates 0.05 < p < 0.10. The p-values and β-values correspond to the multivariable model. All models were corrected for the country effect by placing country as a fixed variable in the model, hence the circle around the figure
Mentions: The country corrected univariable analysis resulted in retaining several variables related with the antimicrobial usage or with each other (Table 1). The associations that remained significant in the multivariable models are shown in the causal path in Fig. 1.Fig. 1

View Article: PubMed Central - PubMed

ABSTRACT

Background: High antimicrobial usage and the threat of antimicrobial resistance highlighted the need for reduced antimicrobial usage in pig production. Prevention of disease however, is necessary to obtain a reduced need for antimicrobial treatment. This study aimed at assessing possible associations between the biosecurity level, antimicrobial usage and farm and production characteristics in order to advice on best practices for a low antimicrobial usage and maximum animal health and production.

Background: A cross-sectional study was conducted in 227 farrow-to-finish pig herds in Belgium, France, Germany and Sweden between December 2012 and December 2013. Associations between biosecurity status, antimicrobial usage, and production parameters were evaluated with multivariable general linear models, according to an assumed causal pathway.

Results: The results showed that higher antimicrobial usage in sows tended to be associated with higher antimicrobial usage from birth until slaughter (p&thinsp;=&thinsp;0.06). The antimicrobial usage from birth until slaughter was positively associated with the number of pathogens vaccinated against (p&thinsp;&lt;&thinsp;0.01). A shorter farrowing rhythm (p&thinsp;&lt;&thinsp;0.01) and a younger weaning age (p&thinsp;=&thinsp;0.06) tended to be also associated with a higher antimicrobial usage from birth until slaughter whereas a better external biosecurity (p&thinsp;&lt;&thinsp;0.01) was related with a lower antimicrobial usage from birth until slaughter.

Conclusion: Management practices such as weaning age and biosecurity measures may be important factors indirectly impacting on antimicrobial usage. We therefore promote a holistic approach when assessing the potential to reduce the need for antimicrobial treatments.

No MeSH data available.


Related in: MedlinePlus