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Myeloid sarcoma: a report of four cases at unusual sites

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ABSTRACT

Background:: Myeloid sarcoma (MS) or granulocytic sarcoma is a rare tumor consisting of myeloid blasts with or without maturation occurring at anatomic sites other than the bone marrow. MS can involve any organ system but shows a predilection for skin, bone, and soft tissues of head and neck region.

Case report:: We report four cases of MS occurring at unusual sites, out of which three were de novo and one was associated with acute myeloid leukemia (AML).

Conclusion:: Although MS is associated with AML, it can rarely present without any existent hematologic disease. Differential diagnosis of a soft tissue mass should include MS even in the absence of leukemia. Establishment of the correct diagnosis depends on morphologic, histochemical, and immunohistochemical examination.

No MeSH data available.


Clinicopathologic features of the four cases
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T1: Clinicopathologic features of the four cases

Mentions: We report four cases of MS to highlight the unusual clinical presentation of this entity and the diagnostic dilemma it can pose (Table 1 (Tab. 1)).


Myeloid sarcoma: a report of four cases at unusual sites
Clinicopathologic features of the four cases
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5304564&req=5

T1: Clinicopathologic features of the four cases
Mentions: We report four cases of MS to highlight the unusual clinical presentation of this entity and the diagnostic dilemma it can pose (Table 1 (Tab. 1)).

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Background:: Myeloid sarcoma (MS) or granulocytic sarcoma is a rare tumor consisting of myeloid blasts with or without maturation occurring at anatomic sites other than the bone marrow. MS can involve any organ system but shows a predilection for skin, bone, and soft tissues of head and neck region.

Case report:: We report four cases of MS occurring at unusual sites, out of which three were de novo and one was associated with acute myeloid leukemia (AML).

Conclusion:: Although MS is associated with AML, it can rarely present without any existent hematologic disease. Differential diagnosis of a soft tissue mass should include MS even in the absence of leukemia. Establishment of the correct diagnosis depends on morphologic, histochemical, and immunohistochemical examination.

No MeSH data available.