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Beat-to-Beat Blood Pressure and Two-dimensional (axial and radial) Motion of the Carotid Artery Wall: Physiological Evaluation of Arterial Stiffness

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ABSTRACT

The physiological relationship between local arterial displacement and blood pressure (BP) plays an integral role in assess- ment of the mechanical properties of arteries. In this study, we used more advanced methods to obtain reliable continuous BP and the displacement of the common carotid artery (CCA) simultaneously. We propose a novel evaluation method for arterial stiffness that relies on determining the physiological relationship between the axial and radial displacements of the CCA wall and beat-to-beat BP. Patients (total of 138) were divided into groups according to the following three criteria: essential hyper- tension (EH) and normotension, male and female, elderly and younger. The Pearson correlation test and canonical correlation analysis showed that the CCA indices were significantly correlated with BP indices (r = 0:787; p < 0:05). The slope of the CCA displacement/pressure curve showed a progressive reduction with increasing age and EH disease occurrence (EH: 0.496 vs. normotension: 0.822; age <= 60:0.585 vs. age > 60:0.783). Our method provides an explicit reference value and relationship for the manner in which the CCA wall responds to changes in BP. Short-term and continuous BP were significantly correlated with CCA displacement and exhibited a close inverse relationship with each subject’s BP and EH, age, and systolic blood pressure.

No MeSH data available.


2-D displacement of the left and right carotid artery and pressure signals as well as their relationship with female and male sex throughout the cardiac cycle.
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f4: 2-D displacement of the left and right carotid artery and pressure signals as well as their relationship with female and male sex throughout the cardiac cycle.

Mentions: Figure 4 and Table 6 present the CCA displacement/pressure curve and different correlations between CCA and BP indices as well as the interrelation between each influencing factor in males and females. The average slope of the male curve was similar to that in females (0.861vs.0.808), and there were significant correlations between CCA and BP indices for both groups (r = 0.940andr = 0.919, respectively; p < 0.05). However, the SBPV_CV, SBPV_SV, DBPV_ARV, and DBPV_RSD mostly had positive coefficients and the SBPV_SD, SBPV_ARV, SBPV_RSD, DBPV_SV, and LAM_ARV had significantly negative coefficients for the correlation in the male group. Similar results were recorded in the female group.


Beat-to-Beat Blood Pressure and Two-dimensional (axial and radial) Motion of the Carotid Artery Wall: Physiological Evaluation of Arterial Stiffness
2-D displacement of the left and right carotid artery and pressure signals as well as their relationship with female and male sex throughout the cardiac cycle.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5304179&req=5

f4: 2-D displacement of the left and right carotid artery and pressure signals as well as their relationship with female and male sex throughout the cardiac cycle.
Mentions: Figure 4 and Table 6 present the CCA displacement/pressure curve and different correlations between CCA and BP indices as well as the interrelation between each influencing factor in males and females. The average slope of the male curve was similar to that in females (0.861vs.0.808), and there were significant correlations between CCA and BP indices for both groups (r = 0.940andr = 0.919, respectively; p < 0.05). However, the SBPV_CV, SBPV_SV, DBPV_ARV, and DBPV_RSD mostly had positive coefficients and the SBPV_SD, SBPV_ARV, SBPV_RSD, DBPV_SV, and LAM_ARV had significantly negative coefficients for the correlation in the male group. Similar results were recorded in the female group.

View Article: PubMed Central - PubMed

ABSTRACT

The physiological relationship between local arterial displacement and blood pressure (BP) plays an integral role in assess- ment of the mechanical properties of arteries. In this study, we used more advanced methods to obtain reliable continuous BP and the displacement of the common carotid artery (CCA) simultaneously. We propose a novel evaluation method for arterial stiffness that relies on determining the physiological relationship between the axial and radial displacements of the CCA wall and beat-to-beat BP. Patients (total of 138) were divided into groups according to the following three criteria: essential hyper- tension (EH) and normotension, male and female, elderly and younger. The Pearson correlation test and canonical correlation analysis showed that the CCA indices were significantly correlated with BP indices (r&thinsp;=&thinsp;0:787; p&thinsp;&lt;&thinsp;0:05). The slope of the CCA displacement/pressure curve showed a progressive reduction with increasing age and EH disease occurrence (EH: 0.496 vs. normotension: 0.822; age&thinsp;&lt;=&thinsp;60:0.585 vs. age&thinsp;&gt;&thinsp;60:0.783). Our method provides an explicit reference value and relationship for the manner in which the CCA wall responds to changes in BP. Short-term and continuous BP were significantly correlated with CCA displacement and exhibited a close inverse relationship with each subject&rsquo;s BP and EH, age, and systolic blood pressure.

No MeSH data available.