Limits...
Effect of vitamin D deficiency on the development of postoperative atrial fibrillation in coronary artery bypass patients

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Introduction:: Various factors may be responsible for the development of postoperative atrial fibrillation (POAF) in coronary artery bypass graft (CABG) patients. In our study, we demonstrated the effect of vitamin D deficiency on the development of POAF.

Methods: In this prospective case control study, patients undergoing elective, isolated CABG were considered. A total of 15 patients (16.6%) who developed POAF during the first five days after surgery made up the POAF group. Seventy-five patients that had a sinus rhythm in the same period were the non-POAF group. The two groups were compared statistically in terms of laboratory, clinical, echocardiographic, operative, and postoperative parameters.

Results:: All patients were in sinus rhythm at discharge. The baseline characteristics of the study groups were comparable. The POAF group had a lower vitamin D level than the non-POAF group (9.0 ± 5.0 and 15.0 ± 8.4 ng/mL, respectively; P=0.007). In the POAF group, the patients’ left atrium diameter and incidence of hypertension (HT) were higher than those of the non-POAF group.

Conclusion: Incidence of POAF was significantly higher in patients with vitamin D deficiency or insufficiency than the patients with vitamin D level in normal range. Therefore vitamin D deficiency or insufficiency may be a predictor of POAF in patients with CABG.

No MeSH data available.


© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC5304095&req=5

Mentions: According to Vittinghoff et al15 the variables those P < 0.10 or P < 0.15 in univariate analyses may be statistically significant in multivariate analyses. Therefore these variables are included to multivariate analyses. For this reason we included the LAD, creatinine, cholesterol and DM to the multivariate analyses. Only one factor was identified as an independent predictor of postoperative AF after CABG surgery in multivariate analysis: the level of vitamin D (OR: 0.856, 95% CI: 0.751–0.976, P = 0.020) (Table 6; Figure 2).


Effect of vitamin D deficiency on the development of postoperative atrial fibrillation in coronary artery bypass patients
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5304095&req=5

Mentions: According to Vittinghoff et al15 the variables those P < 0.10 or P < 0.15 in univariate analyses may be statistically significant in multivariate analyses. Therefore these variables are included to multivariate analyses. For this reason we included the LAD, creatinine, cholesterol and DM to the multivariate analyses. Only one factor was identified as an independent predictor of postoperative AF after CABG surgery in multivariate analysis: the level of vitamin D (OR: 0.856, 95% CI: 0.751–0.976, P = 0.020) (Table 6; Figure 2).

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Introduction:: Various factors may be responsible for the development of postoperative atrial fibrillation (POAF) in coronary artery bypass graft (CABG) patients. In our study, we demonstrated the effect of vitamin D deficiency on the development of POAF.

Methods: In this prospective case control study, patients undergoing elective, isolated CABG were considered. A total of 15 patients (16.6%) who developed POAF during the first five days after surgery made up the POAF group. Seventy-five patients that had a sinus rhythm in the same period were the non-POAF group. The two groups were compared statistically in terms of laboratory, clinical, echocardiographic, operative, and postoperative parameters.

Results:: All patients were in sinus rhythm at discharge. The baseline characteristics of the study groups were comparable. The POAF group had a lower vitamin D level than the non-POAF group (9.0 &plusmn; 5.0 and 15.0 &plusmn; 8.4 ng/mL, respectively; P=0.007). In the POAF group, the patients&rsquo; left atrium diameter and incidence of hypertension (HT) were higher than those of the non-POAF group.

Conclusion: Incidence of POAF was significantly higher in patients with vitamin D deficiency or insufficiency than the patients with vitamin D level in normal range. Therefore vitamin D deficiency or insufficiency may be a predictor of POAF in patients with CABG.

No MeSH data available.