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Effect of Anodal-tDCS on Event-Related Potentials: A Controlled Study

View Article: PubMed Central - PubMed

ABSTRACT

We aim to measure the postintervention effects of A-tDCS (anodal-tDCS) on brain potentials commonly used in BCI applications, namely, Event-Related Desynchronization (ERD), Event-Related Synchronization (ERS), and P300. Ten subjects were given sham and 1.5 mA A-tDCS for 15 minutes on two separate experiments in a double-blind, randomized order. Postintervention EEG was recorded while subjects were asked to perform a spelling task based on the “oddball paradigm” while P300 power was measured. Additionally, ERD and ERS were measured while subjects performed mental motor imagery tasks. ANOVA results showed that the absolute P300 power exhibited a statistically significant difference between sham and A-tDCS when measured over channel Pz (p = 0.0002). However, the difference in ERD and ERS power was found to be statistically insignificant, in controversion of the the mainstay of the litrature on the subject. The outcomes confirm the possible postintervention effect of tDCS on the P300 response. Heightening P300 response using A-tDCS may help improve the accuracy of P300 spellers for neurologically impaired subjects. Additionally, it may help the development of neurorehabilitation methods targeting the parietal lobe.

No MeSH data available.


Box and whisker plot of the step in relative ERS power in μV2 for C3 before and after motor imagery cue for the 10 participants.
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fig3: Box and whisker plot of the step in relative ERS power in μV2 for C3 before and after motor imagery cue for the 10 participants.

Mentions: Relative Power Difference (RPD) in ERD is measured for individual subjects across C3 for both real A-tDCS and sham A-tDCS conditions. A one-way ANOVA resulted in a p value of 0.46. The box plot in Figure 2 summarizes the data in the two groups. The overlap of two groups is clearly visible, and this supports the above p value. The same analysis was carried out for the RPD of ERS across C3. The box plot in Figure 3 summarizes the data in the two groups and clearly depicts overlap in the data from the two groups (real A-tDCS and sham A-tDCS). A one-way ANOVA test of mean difference yielded a p value of 0.49. The average power increment after application of the A-tDCS was 26.17%.


Effect of Anodal-tDCS on Event-Related Potentials: A Controlled Study
Box and whisker plot of the step in relative ERS power in μV2 for C3 before and after motor imagery cue for the 10 participants.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5121578&req=5

fig3: Box and whisker plot of the step in relative ERS power in μV2 for C3 before and after motor imagery cue for the 10 participants.
Mentions: Relative Power Difference (RPD) in ERD is measured for individual subjects across C3 for both real A-tDCS and sham A-tDCS conditions. A one-way ANOVA resulted in a p value of 0.46. The box plot in Figure 2 summarizes the data in the two groups. The overlap of two groups is clearly visible, and this supports the above p value. The same analysis was carried out for the RPD of ERS across C3. The box plot in Figure 3 summarizes the data in the two groups and clearly depicts overlap in the data from the two groups (real A-tDCS and sham A-tDCS). A one-way ANOVA test of mean difference yielded a p value of 0.49. The average power increment after application of the A-tDCS was 26.17%.

View Article: PubMed Central - PubMed

ABSTRACT

We aim to measure the postintervention effects of A-tDCS (anodal-tDCS) on brain potentials commonly used in BCI applications, namely, Event-Related Desynchronization (ERD), Event-Related Synchronization (ERS), and P300. Ten subjects were given sham and 1.5 mA A-tDCS for 15 minutes on two separate experiments in a double-blind, randomized order. Postintervention EEG was recorded while subjects were asked to perform a spelling task based on the “oddball paradigm” while P300 power was measured. Additionally, ERD and ERS were measured while subjects performed mental motor imagery tasks. ANOVA results showed that the absolute P300 power exhibited a statistically significant difference between sham and A-tDCS when measured over channel Pz (p = 0.0002). However, the difference in ERD and ERS power was found to be statistically insignificant, in controversion of the the mainstay of the litrature on the subject. The outcomes confirm the possible postintervention effect of tDCS on the P300 response. Heightening P300 response using A-tDCS may help improve the accuracy of P300 spellers for neurologically impaired subjects. Additionally, it may help the development of neurorehabilitation methods targeting the parietal lobe.

No MeSH data available.