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Diffuse Infiltrative Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Completely Cured by Transcatheter Arterial Chemoembolization: Case Report with 8-Year Follow-Up

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ABSTRACT

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and its treatment options are determined by shape, liver function, loci, and stages of cancer. Diffuse type of infiltrative HCC accompanied by portal vein tumor thrombosis (PVTT) has the poorest prognosis among other HCCs and there are no other prominent treatment options than systemic chemotherapy. In this study, we report a case of a 56-year-old man with diffuse infiltrative HCC accompanied by PVTT who achieved complete remission for 8 years after receiving conventional transcatheter arterial chemoembolization using adriamycin and gelfoam.

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Transcatheter arterial chemoembolization. Large tumor staining (white arrows) and portal vein tumor thrombosis staining (dotted circle) was found. A total of 18 mL mixture of adriamycin 50 mg and lipiodol 15 mL was infused and embolization using gelfoam was done.
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Figure 2: Transcatheter arterial chemoembolization. Large tumor staining (white arrows) and portal vein tumor thrombosis staining (dotted circle) was found. A total of 18 mL mixture of adriamycin 50 mg and lipiodol 15 mL was infused and embolization using gelfoam was done.

Mentions: Outcome of TACE showed existence of a huge tumor staining in segments 4 and 8, along with the staining of right PVTT. A mixture (total 18 mL) of adriamycin 50 mg and lipiodol 15 mL was administered (Fig 2). Dynamic liver CT scan taken after about a month showed large and heterogeneous lipiodol uptake mainly at segments 4 and 8 (Fig 3a). The left and the right PVTT were still found, although they were reduced in size. Another small partial lipiodol uptake was found in segments 7 and 8. Blood testing revealed reduced AFP and des-γ carboxyprothrombin levels (5,685 ng/mL and 162 mAU/mL, respectively).


Diffuse Infiltrative Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Completely Cured by Transcatheter Arterial Chemoembolization: Case Report with 8-Year Follow-Up
Transcatheter arterial chemoembolization. Large tumor staining (white arrows) and portal vein tumor thrombosis staining (dotted circle) was found. A total of 18 mL mixture of adriamycin 50 mg and lipiodol 15 mL was infused and embolization using gelfoam was done.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5121572&req=5

Figure 2: Transcatheter arterial chemoembolization. Large tumor staining (white arrows) and portal vein tumor thrombosis staining (dotted circle) was found. A total of 18 mL mixture of adriamycin 50 mg and lipiodol 15 mL was infused and embolization using gelfoam was done.
Mentions: Outcome of TACE showed existence of a huge tumor staining in segments 4 and 8, along with the staining of right PVTT. A mixture (total 18 mL) of adriamycin 50 mg and lipiodol 15 mL was administered (Fig 2). Dynamic liver CT scan taken after about a month showed large and heterogeneous lipiodol uptake mainly at segments 4 and 8 (Fig 3a). The left and the right PVTT were still found, although they were reduced in size. Another small partial lipiodol uptake was found in segments 7 and 8. Blood testing revealed reduced AFP and des-γ carboxyprothrombin levels (5,685 ng/mL and 162 mAU/mL, respectively).

View Article: PubMed Central - PubMed

ABSTRACT

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and its treatment options are determined by shape, liver function, loci, and stages of cancer. Diffuse type of infiltrative HCC accompanied by portal vein tumor thrombosis (PVTT) has the poorest prognosis among other HCCs and there are no other prominent treatment options than systemic chemotherapy. In this study, we report a case of a 56-year-old man with diffuse infiltrative HCC accompanied by PVTT who achieved complete remission for 8 years after receiving conventional transcatheter arterial chemoembolization using adriamycin and gelfoam.

No MeSH data available.


Related in: MedlinePlus