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A Giant Gastrointestinal Stromal Tumor of the Stomach with Extramural Growth

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ABSTRACT

A 76-year-old man presented to our hospital with abdominal distention and loss of appetite. The 10% of weight lost relative to this patient in 1 month. Abdominal computed tomography and magnetic resonance imaging revealed a giant mass, with a major axis of 23 cm, containing solid components, not involving the upper abdominal organs. Esophagogastroduodenoscopy showed extramural compression from the middle gastric body to the antrum, as well as a normal mucosal surface. These findings were suggestive of a gastrointestinal stromal tumor attached to the anterior wall of the stomach without metastasis or invasion. Partial gastrectomy was performed for tumor resection, and the patient was subsequently treated with adjuvant imatinib. We report a rare case of a large extramural gastrointestinal stromal tumor of the stomach that was larger than 20 cm in diameter and present a pertinent literature review.

No MeSH data available.


Related in: MedlinePlus

Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosa side. Most of the tumor was covered in a capsule but the capsule had broken in some places and parenchyma was disintegrating (a). The cut surface was clearly demarcated, pale pink, and solid. It was accompanied by severe bleeding necrosis (b).
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Figure 2: Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosa side. Most of the tumor was covered in a capsule but the capsule had broken in some places and parenchyma was disintegrating (a). The cut surface was clearly demarcated, pale pink, and solid. It was accompanied by severe bleeding necrosis (b).

Mentions: Surgical findings indicated that a tumor had developed from the lesser curvature side of the stomach. It adhered to the transverse mesocolon, liver, and gallbladder; however, no invasion and metastatic lesions were detected. Therefore, distal gastrectomy and Roux-en-Y reconstruction were performed. Cholecystectomy was also performed for the gallstones. Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosal side. Most of the tumor was covered in a capsule, but the capsule had broken in some places and parenchyma was disintegrating. The removed mass was pale pink, solid, and clearly demarcated. Severe bleeding necrosis was observed (fig. 2).


A Giant Gastrointestinal Stromal Tumor of the Stomach with Extramural Growth
Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosa side. Most of the tumor was covered in a capsule but the capsule had broken in some places and parenchyma was disintegrating (a). The cut surface was clearly demarcated, pale pink, and solid. It was accompanied by severe bleeding necrosis (b).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5121561&req=5

Figure 2: Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosa side. Most of the tumor was covered in a capsule but the capsule had broken in some places and parenchyma was disintegrating (a). The cut surface was clearly demarcated, pale pink, and solid. It was accompanied by severe bleeding necrosis (b).
Mentions: Surgical findings indicated that a tumor had developed from the lesser curvature side of the stomach. It adhered to the transverse mesocolon, liver, and gallbladder; however, no invasion and metastatic lesions were detected. Therefore, distal gastrectomy and Roux-en-Y reconstruction were performed. Cholecystectomy was also performed for the gallstones. Macroscopic findings of the resected specimen showed a giant tumor of 23 × 20 × 13 cm on the gastric serosal side. Most of the tumor was covered in a capsule, but the capsule had broken in some places and parenchyma was disintegrating. The removed mass was pale pink, solid, and clearly demarcated. Severe bleeding necrosis was observed (fig. 2).

View Article: PubMed Central - PubMed

ABSTRACT

A 76-year-old man presented to our hospital with abdominal distention and loss of appetite. The 10% of weight lost relative to this patient in 1 month. Abdominal computed tomography and magnetic resonance imaging revealed a giant mass, with a major axis of 23 cm, containing solid components, not involving the upper abdominal organs. Esophagogastroduodenoscopy showed extramural compression from the middle gastric body to the antrum, as well as a normal mucosal surface. These findings were suggestive of a gastrointestinal stromal tumor attached to the anterior wall of the stomach without metastasis or invasion. Partial gastrectomy was performed for tumor resection, and the patient was subsequently treated with adjuvant imatinib. We report a rare case of a large extramural gastrointestinal stromal tumor of the stomach that was larger than 20 cm in diameter and present a pertinent literature review.

No MeSH data available.


Related in: MedlinePlus