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Rectal gastrointestinal stromal tumor with metastasis to the penis: Case report and review of literature

View Article: PubMed Central - PubMed

ABSTRACT

The first reported case of a rectal GIST with metastasis to the penis is documented by this report.

The primary cancer was treated with neoadjuvant chemotherapy and abdominoperineal resection.

Biopsies of lesions identified on follow-up imaging were consistent with metastatic GIST.

Metastasectomy and adjuvant chemotherapy have been utilized to help prolong survival.

Metastasectomy and adjuvant chemotherapy have been utilized to help prolong survival.

No MeSH data available.


Axial view of pelvis MRI. Axial view of the pelvis on MRI revealed a right corpus cavernosum mass.
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fig0015: Axial view of pelvis MRI. Axial view of the pelvis on MRI revealed a right corpus cavernosum mass.

Mentions: The patient continued to experience worsening right testicular, right hip, and perineal pain, which was moderately relieved by application of a heating pad and sitz baths but not by narcotic pain medication. On examination, the proximal penile shaft was tender to palpation, and an ill-defined mass was noted in the right perineum extending from the base of the penis to the penoscrotal junction. A pelvic MRI revealed an 8.4 × 4.3 × 3.6 cm enhancing mass in the right corpus cavernosum (Fig. 3, Fig. 4). The patient was referred to Urologic Oncology. Needle biopsies of the penile lesion were obtained, and histologic evaluation of these specimens revealed a cellular spindle cell tumor with mitoses, positive CD117 immunostain, and negative for desmin, findings which are consistent with metastatic GIST.


Rectal gastrointestinal stromal tumor with metastasis to the penis: Case report and review of literature
Axial view of pelvis MRI. Axial view of the pelvis on MRI revealed a right corpus cavernosum mass.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5120263&req=5

fig0015: Axial view of pelvis MRI. Axial view of the pelvis on MRI revealed a right corpus cavernosum mass.
Mentions: The patient continued to experience worsening right testicular, right hip, and perineal pain, which was moderately relieved by application of a heating pad and sitz baths but not by narcotic pain medication. On examination, the proximal penile shaft was tender to palpation, and an ill-defined mass was noted in the right perineum extending from the base of the penis to the penoscrotal junction. A pelvic MRI revealed an 8.4 × 4.3 × 3.6 cm enhancing mass in the right corpus cavernosum (Fig. 3, Fig. 4). The patient was referred to Urologic Oncology. Needle biopsies of the penile lesion were obtained, and histologic evaluation of these specimens revealed a cellular spindle cell tumor with mitoses, positive CD117 immunostain, and negative for desmin, findings which are consistent with metastatic GIST.

View Article: PubMed Central - PubMed

ABSTRACT

The first reported case of a rectal GIST with metastasis to the penis is documented by this report.

The primary cancer was treated with neoadjuvant chemotherapy and abdominoperineal resection.

Biopsies of lesions identified on follow-up imaging were consistent with metastatic GIST.

Metastasectomy and adjuvant chemotherapy have been utilized to help prolong survival.

Metastasectomy and adjuvant chemotherapy have been utilized to help prolong survival.

No MeSH data available.