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Adaptive responses of cardiac function to fetal postural change as gestational age increases

View Article: PubMed Central - PubMed

ABSTRACT

Objective: The cardiovascular system maintains homeostasis through a series of adaptive responses to physiological requirements. However, little is known about the adaptation of fetal cardiac function to gravity, according to gestational age. In the present study, we aimed to evaluate the adaptive responses of cardiac function to postural changes, using Tei index measurements.

Methods: Fetal echocardiography and Doppler examination were performed on 114 women with vertex singleton pregnancies at 19 to 40 weeks' gestation. Participants were placed in an upright seated position, and the Tei index for fetal left ventricular cardiac function was measured. The women were then moved into a supine position and the Tei index was re-measured.

Results: The mean Tei index when measured in an upright seated position was significantly lower than that measured in a supine positioning for all fetuses (0.528±0.103 vs. 0.555±0.106, P=0.014, respectively). This difference was also noted in fetuses with a gestational age of 28–40 weeks (0.539±0.107 vs. 0.574±0.102, P=0.011, respectively). However, there was no difference in the Tei index between an upright seated and a supine position among fetuses with a gestational age of <28 weeks (0.505±0.091 vs. 0.516±0.103, P=0.571, respectively).

Conclusion: Postural changes from an upright seated to a supine position result in an increased Tei index after a gestational age of 28 weeks. This appears to reflect maturation in the adaptive responses of the fetal cardiovascular system to postural changes.

No MeSH data available.


Related in: MedlinePlus

Isovolumic contraction time (A), ejection time (B), and isovolumic relaxation time (C) according to maternal postural changes, among all fetuses.
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Figure 2: Isovolumic contraction time (A), ejection time (B), and isovolumic relaxation time (C) according to maternal postural changes, among all fetuses.

Mentions: The mean participant age and fetal gestational age were 30.23±2.31 years and 29.49±6.49 weeks, respectively. The Tei index was assessed in all cases. The mean Tei index when mothers were placed in an upright seated position was significantly lower than that in the supine position, among all fetuses (Fig. 1). However, ICT, ET, and IRT were not different between the upright seated and supine positions (Fig. 2).


Adaptive responses of cardiac function to fetal postural change as gestational age increases
Isovolumic contraction time (A), ejection time (B), and isovolumic relaxation time (C) according to maternal postural changes, among all fetuses.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5120061&req=5

Figure 2: Isovolumic contraction time (A), ejection time (B), and isovolumic relaxation time (C) according to maternal postural changes, among all fetuses.
Mentions: The mean participant age and fetal gestational age were 30.23±2.31 years and 29.49±6.49 weeks, respectively. The Tei index was assessed in all cases. The mean Tei index when mothers were placed in an upright seated position was significantly lower than that in the supine position, among all fetuses (Fig. 1). However, ICT, ET, and IRT were not different between the upright seated and supine positions (Fig. 2).

View Article: PubMed Central - PubMed

ABSTRACT

Objective: The cardiovascular system maintains homeostasis through a series of adaptive responses to physiological requirements. However, little is known about the adaptation of fetal cardiac function to gravity, according to gestational age. In the present study, we aimed to evaluate the adaptive responses of cardiac function to postural changes, using Tei index measurements.

Methods: Fetal echocardiography and Doppler examination were performed on 114 women with vertex singleton pregnancies at 19 to 40 weeks' gestation. Participants were placed in an upright seated position, and the Tei index for fetal left ventricular cardiac function was measured. The women were then moved into a supine position and the Tei index was re-measured.

Results: The mean Tei index when measured in an upright seated position was significantly lower than that measured in a supine positioning for all fetuses (0.528±0.103 vs. 0.555±0.106, P=0.014, respectively). This difference was also noted in fetuses with a gestational age of 28–40 weeks (0.539±0.107 vs. 0.574±0.102, P=0.011, respectively). However, there was no difference in the Tei index between an upright seated and a supine position among fetuses with a gestational age of <28 weeks (0.505±0.091 vs. 0.516±0.103, P=0.571, respectively).

Conclusion: Postural changes from an upright seated to a supine position result in an increased Tei index after a gestational age of 28 weeks. This appears to reflect maturation in the adaptive responses of the fetal cardiovascular system to postural changes.

No MeSH data available.


Related in: MedlinePlus