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Validity of predictive factors of acute complicated appendicitis

View Article: PubMed Central - PubMed

ABSTRACT

Background: Our previous retrospective study revealed the three preoperative predictors of complicated appendicitis (perforated or gangrenous appendicitis), which are body temperature ≥37.4 °C, C-reactive protein ≥4.7 mg/dl, and fluid collection surrounding the appendix on computed tomography. We reported here an additional prospective study to verify our ability to predict complicated appendicitis using the three preoperative predictors and thus facilitate better informed decisions regarding emergency surgery during night or holiday shifts.

Methods: We prospectively evaluated 116 adult patients who underwent surgery for acute appendicitis from January 2013 to October 2014. Ninety patients with one or more predictive factors of complicated appendicitis underwent immediate surgery regardless of the time of patient’s presentation. Twenty-six patients had no predictive factors and thus were suspected to have uncomplicated appendicitis. Of the 26 patients, 14 who presented to our hospital during office hours underwent immediate surgery. The other 12 patients who presented to our hospital at night or on a holiday underwent short, in-hospital delayed surgery during office hours.

Results: All patients with no predictive factors had uncomplicated appendicitis, whereas 37 %, 81 %, and 100 % of patients with one, two, or all three factors, respectively, were diagnosed with complicated appendicitis. The emergency operation rate decreased from 83 % before to 58 % after adopting this scoring system, but no significant differences in postoperative complication rates and hospitalization periods were observed.

Conclusions: The above-mentioned preoperative factors predictive of complicated appendicitis preoperatively are useful for emergency surgical decisions and reduce the burdens on surgeons and medical staff.

No MeSH data available.


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Algorithm indicating the diagnosis and treatment strategies for acute appendicitis
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Fig1: Algorithm indicating the diagnosis and treatment strategies for acute appendicitis

Mentions: Our strategies of the diagnostic strategies of and for acute appendicitis are shown in Fig. 1. Clinical suspicion of acute appendicitis is made based on the routine use of Alvarado [6] and appendicitis inflammatory response (AIR) scores [7]. In the absence of contraindication to CT use such as pregnancy, CT scans are performed for patients with an Alvarado score ≥ of 5 or more and/or AIR score ≥ of 2 or more, if patients had no contraindication of use of CT scan such as pregnancy. A diagnosis of acute appendicitis is given if the patient has when positive CT findings on all of the following CT findings: a short appendix diameter greater than >6 mm, a thickened wall of the appendix, and absence of gas in the appendicular lumen. Decisions to surgery was performed when the patient was positive for at least one of the following findings: the existence of peritoneal irritation, a short appendix diameter ≥10 mm, stone in the appendix root, and ascites around the appendix or Douglas fossa. Patients without these factors received non-operative treatment.Fig. 1


Validity of predictive factors of acute complicated appendicitis
Algorithm indicating the diagnosis and treatment strategies for acute appendicitis
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5037592&req=5

Fig1: Algorithm indicating the diagnosis and treatment strategies for acute appendicitis
Mentions: Our strategies of the diagnostic strategies of and for acute appendicitis are shown in Fig. 1. Clinical suspicion of acute appendicitis is made based on the routine use of Alvarado [6] and appendicitis inflammatory response (AIR) scores [7]. In the absence of contraindication to CT use such as pregnancy, CT scans are performed for patients with an Alvarado score ≥ of 5 or more and/or AIR score ≥ of 2 or more, if patients had no contraindication of use of CT scan such as pregnancy. A diagnosis of acute appendicitis is given if the patient has when positive CT findings on all of the following CT findings: a short appendix diameter greater than >6 mm, a thickened wall of the appendix, and absence of gas in the appendicular lumen. Decisions to surgery was performed when the patient was positive for at least one of the following findings: the existence of peritoneal irritation, a short appendix diameter ≥10 mm, stone in the appendix root, and ascites around the appendix or Douglas fossa. Patients without these factors received non-operative treatment.Fig. 1

View Article: PubMed Central - PubMed

ABSTRACT

Background: Our previous retrospective study revealed the three preoperative predictors of complicated appendicitis (perforated or gangrenous appendicitis), which are body temperature ≥37.4 °C, C-reactive protein ≥4.7 mg/dl, and fluid collection surrounding the appendix on computed tomography. We reported here an additional prospective study to verify our ability to predict complicated appendicitis using the three preoperative predictors and thus facilitate better informed decisions regarding emergency surgery during night or holiday shifts.

Methods: We prospectively evaluated 116 adult patients who underwent surgery for acute appendicitis from January 2013 to October 2014. Ninety patients with one or more predictive factors of complicated appendicitis underwent immediate surgery regardless of the time of patient’s presentation. Twenty-six patients had no predictive factors and thus were suspected to have uncomplicated appendicitis. Of the 26 patients, 14 who presented to our hospital during office hours underwent immediate surgery. The other 12 patients who presented to our hospital at night or on a holiday underwent short, in-hospital delayed surgery during office hours.

Results: All patients with no predictive factors had uncomplicated appendicitis, whereas 37 %, 81 %, and 100 % of patients with one, two, or all three factors, respectively, were diagnosed with complicated appendicitis. The emergency operation rate decreased from 83 % before to 58 % after adopting this scoring system, but no significant differences in postoperative complication rates and hospitalization periods were observed.

Conclusions: The above-mentioned preoperative factors predictive of complicated appendicitis preoperatively are useful for emergency surgical decisions and reduce the burdens on surgeons and medical staff.

No MeSH data available.


Related in: MedlinePlus