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In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy

View Article: PubMed Central - PubMed

ABSTRACT

Chronic or sustained hyperglycemia associated to diabetes mellitus leads to many medical complications, thus, it is necessary to track the evolution of patients for providing the adequate management of the disease that is required for the restoration of the carbohydrate metabolism to a normal state. In this paper, a novel monitoring approach based on mm-wave spectroscopy is comprehensively described and experimentally validated using living animal models as target. The measurement method has proved the possibility of non-invasive, in-vivo, detection of hyperglycemia-associated conditions in different mouse models, making possible to clearly differentiate between several hyperglycemic states.

No MeSH data available.


Basics of the measurement set-up.
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f1: Basics of the measurement set-up.

Mentions: As the basis of the proposed method for the monitoring of sustained hyperglycemia, the transmittance of a fold of the skin at the nape of the mice is measured at 25 equally spaced frequencies located within the W-band (75–110 GHz) in the mm-wave range, a block diagram of the measurement head is shown in Fig. 1 (see Methods section for further details).


In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy
Basics of the measurement set-up.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037419&req=5

f1: Basics of the measurement set-up.
Mentions: As the basis of the proposed method for the monitoring of sustained hyperglycemia, the transmittance of a fold of the skin at the nape of the mice is measured at 25 equally spaced frequencies located within the W-band (75–110 GHz) in the mm-wave range, a block diagram of the measurement head is shown in Fig. 1 (see Methods section for further details).

View Article: PubMed Central - PubMed

ABSTRACT

Chronic or sustained hyperglycemia associated to diabetes mellitus leads to many medical complications, thus, it is necessary to track the evolution of patients for providing the adequate management of the disease that is required for the restoration of the carbohydrate metabolism to a normal state. In this paper, a novel monitoring approach based on mm-wave spectroscopy is comprehensively described and experimentally validated using living animal models as target. The measurement method has proved the possibility of non-invasive, in-vivo, detection of hyperglycemia-associated conditions in different mouse models, making possible to clearly differentiate between several hyperglycemic states.

No MeSH data available.