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An epidemiological analysis of acute flaccid paralysis in Khuzestan Province, southwest Iran, from 2006 to 2010

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: Investigations into the epidemiology of acute flaccid paralysis (AFP) are an essential strategic component of the Global Poliomyelitis Eradication Initiative of the World Health Organization (WHO), and are part of the certification process for polio eradication worldwide. This is an epidemiological report of AFP incidence in children less than 15 years old in southwest Iran.

Methods:: This was a retrospective cohort study, carried out based on WHO guidelines, in which we reviewed non-polio AFP cases recorded from January 2006 to December 2010 in different regions of Khuzestan Province, southwest Iran. In this study, the records of all children under 15 years old with AFP were evaluated.

Results:: During a 5-year period, 137 cases of AFP were reported (incidence rate, 2.21 per 100,000 children <15 years old). More than 50% (73 of 137) of the cases were boys, and 52.6% (72 of 137) were under 5 years of age, with a mean age of 5.39±3.98 years. The incidence of AFP was significantly higher in older children (p=0.001). The most common cause of paralysis was Guillain-Barré syndrome (117 of 137). None of the cases were diagnosed with acute poliomyelitis.

Conclusions:: In this study, we found that the incidence rate of AFP in the region was almost in agreement with the expected incidence of AFP in children less than 15 years old; therefore, the AFP surveillance program in Khuzestan Province is satisfactory in terms of reliability and effectiveness. Nevertheless, routine vaccination against polio and ensuring that patients with AFP receive follow-up are essential for eradicating polio.

No MeSH data available.


Related in: MedlinePlus

Incidence rate of non-polio acute flaccid paralysis (AFP) per 100,000 children under 15 years old in Khuzestan, Iran (2006-2010).
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f1-epih-38-e2016030: Incidence rate of non-polio acute flaccid paralysis (AFP) per 100,000 children under 15 years old in Khuzestan, Iran (2006-2010).

Mentions: Based on reports from the Statistical Center of Iran [12], the population of children less than 15 years old in Khuzestan Province in the years of the study was 1,221,257; 1,226,167; 1,234,262; 1,245,627 and 1,260,363, respectively. Accordingly, the incidence rate in each year was calculated as the total number of cases per population of children less than 15 years old in that year, multiplied by 100,000 (Figure 1). The average AFP incidence rate in this 5-year period was calculated to be 2.21 per 100,000 children under 15 years old.


An epidemiological analysis of acute flaccid paralysis in Khuzestan Province, southwest Iran, from 2006 to 2010
Incidence rate of non-polio acute flaccid paralysis (AFP) per 100,000 children under 15 years old in Khuzestan, Iran (2006-2010).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037358&req=5

f1-epih-38-e2016030: Incidence rate of non-polio acute flaccid paralysis (AFP) per 100,000 children under 15 years old in Khuzestan, Iran (2006-2010).
Mentions: Based on reports from the Statistical Center of Iran [12], the population of children less than 15 years old in Khuzestan Province in the years of the study was 1,221,257; 1,226,167; 1,234,262; 1,245,627 and 1,260,363, respectively. Accordingly, the incidence rate in each year was calculated as the total number of cases per population of children less than 15 years old in that year, multiplied by 100,000 (Figure 1). The average AFP incidence rate in this 5-year period was calculated to be 2.21 per 100,000 children under 15 years old.

View Article: PubMed Central - PubMed

ABSTRACT

Objectives:: Investigations into the epidemiology of acute flaccid paralysis (AFP) are an essential strategic component of the Global Poliomyelitis Eradication Initiative of the World Health Organization (WHO), and are part of the certification process for polio eradication worldwide. This is an epidemiological report of AFP incidence in children less than 15 years old in southwest Iran.

Methods:: This was a retrospective cohort study, carried out based on WHO guidelines, in which we reviewed non-polio AFP cases recorded from January 2006 to December 2010 in different regions of Khuzestan Province, southwest Iran. In this study, the records of all children under 15 years old with AFP were evaluated.

Results:: During a 5-year period, 137 cases of AFP were reported (incidence rate, 2.21 per 100,000 children <15 years old). More than 50% (73 of 137) of the cases were boys, and 52.6% (72 of 137) were under 5 years of age, with a mean age of 5.39±3.98 years. The incidence of AFP was significantly higher in older children (p=0.001). The most common cause of paralysis was Guillain-Barré syndrome (117 of 137). None of the cases were diagnosed with acute poliomyelitis.

Conclusions:: In this study, we found that the incidence rate of AFP in the region was almost in agreement with the expected incidence of AFP in children less than 15 years old; therefore, the AFP surveillance program in Khuzestan Province is satisfactory in terms of reliability and effectiveness. Nevertheless, routine vaccination against polio and ensuring that patients with AFP receive follow-up are essential for eradicating polio.

No MeSH data available.


Related in: MedlinePlus