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Seroprevalence and associated risk factors of pseudorabies in Shandong province of China

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ABSTRACT

A cross-sectional serological study was conducted in Shandong province of China to determine the seroprevalence and risk factors associated with seropositivity due to pseudorabies virus (PRV) infection in small- and medium-sized farrow-to-finish herds following outbreaks of variant PRV strains. A total of 6,035 blood samples from 224 randomly selected herds were screened. The results showed that 25.0% of the herds and 56.7% of the serum samples were seropositive for field strains of PRV. Herds consisting of 50–100 breeding sows had higher herd seroprevalence and serum sample seroprevalence than larger herds. Both the highest herd seroprevalence and highest serum sample seroprevalence were observed in western Shandong, followed northern Shandong. Based on univariate analysis, the following risk factors were utilized in subsequent multivariable logistic regression analysis: region, herd size, weight of purchased gilts, and all-in/all-out practice. Upon multivariate analysis, region, herd size, weight of purchased gilts and all-in/all-out practice were significantly associated with PRV herd seropositivity. These findings indicate that we are facing a serious situation in the prevention and control of pseudorabies. The results could help predict the next outbreak and set out control measures.

No MeSH data available.


Sample seroprevalence of different production phases in the five regions. (A) Sample seroprevalence of fattening pigs. (B) Sample seroprevalence of gilts. (C) Sample seroprevalence of multiparous sows.
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Figure 3: Sample seroprevalence of different production phases in the five regions. (A) Sample seroprevalence of fattening pigs. (B) Sample seroprevalence of gilts. (C) Sample seroprevalence of multiparous sows.

Mentions: Based on their economic level and convention, 17 cities of Shandong province can be divided into five regions (Fig. 1). Both sample seroprevalence (panel A in Fig. 2) and herd seroprevalence (panel B in Fig. 2) varied with herd geographical location, and they showed a similar tendency toward west > north > central > south > east (Fig. 2). Among regions, the seroprevalence of 50‒100 sow herds, as well as the seroprevalence of samples collected from such herds, was highest in the north, while the seroprevalence of larger herds, as well as the seroprevalence of samples collected from such herds, was highest in the west (panels A and B in Fig. 2). The average sample seroprevalence of fattening pigs was 28.4% (361/1272). Among the five regions, the sample seroprevalence of fattening pigs in the west was highest, while that from the east was lowest, with rates of 51.6% (96/186) and 16.9% (68/403), respectively. The sample seroprevalence of fattening pigs from the other four regions varied with herd size, except for the central region, and smaller herds had higher sample seroprevalence (panel A in Fig. 3). The average seroprevalence of gilts was 20.9% (403/1929). Among the five regions, the sample seroprevalence of gilts was highest in the south and lowest in the east, with rates of 29.0% (60/207) and 10.8% (54/499), respectively (panel B in Fig. 3). The sample seroprevalence of multiparous sows was 26.3% (745/2834). Among the five regions, the sample seroprevalence of multiparous sows was higher in the west and north than in the other three regions (panel C in Fig. 3).


Seroprevalence and associated risk factors of pseudorabies in Shandong province of China
Sample seroprevalence of different production phases in the five regions. (A) Sample seroprevalence of fattening pigs. (B) Sample seroprevalence of gilts. (C) Sample seroprevalence of multiparous sows.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037304&req=5

Figure 3: Sample seroprevalence of different production phases in the five regions. (A) Sample seroprevalence of fattening pigs. (B) Sample seroprevalence of gilts. (C) Sample seroprevalence of multiparous sows.
Mentions: Based on their economic level and convention, 17 cities of Shandong province can be divided into five regions (Fig. 1). Both sample seroprevalence (panel A in Fig. 2) and herd seroprevalence (panel B in Fig. 2) varied with herd geographical location, and they showed a similar tendency toward west > north > central > south > east (Fig. 2). Among regions, the seroprevalence of 50‒100 sow herds, as well as the seroprevalence of samples collected from such herds, was highest in the north, while the seroprevalence of larger herds, as well as the seroprevalence of samples collected from such herds, was highest in the west (panels A and B in Fig. 2). The average sample seroprevalence of fattening pigs was 28.4% (361/1272). Among the five regions, the sample seroprevalence of fattening pigs in the west was highest, while that from the east was lowest, with rates of 51.6% (96/186) and 16.9% (68/403), respectively. The sample seroprevalence of fattening pigs from the other four regions varied with herd size, except for the central region, and smaller herds had higher sample seroprevalence (panel A in Fig. 3). The average seroprevalence of gilts was 20.9% (403/1929). Among the five regions, the sample seroprevalence of gilts was highest in the south and lowest in the east, with rates of 29.0% (60/207) and 10.8% (54/499), respectively (panel B in Fig. 3). The sample seroprevalence of multiparous sows was 26.3% (745/2834). Among the five regions, the sample seroprevalence of multiparous sows was higher in the west and north than in the other three regions (panel C in Fig. 3).

View Article: PubMed Central - PubMed

ABSTRACT

A cross-sectional serological study was conducted in Shandong province of China to determine the seroprevalence and risk factors associated with seropositivity due to pseudorabies virus (PRV) infection in small- and medium-sized farrow-to-finish herds following outbreaks of variant PRV strains. A total of 6,035 blood samples from 224 randomly selected herds were screened. The results showed that 25.0% of the herds and 56.7% of the serum samples were seropositive for field strains of PRV. Herds consisting of 50–100 breeding sows had higher herd seroprevalence and serum sample seroprevalence than larger herds. Both the highest herd seroprevalence and highest serum sample seroprevalence were observed in western Shandong, followed northern Shandong. Based on univariate analysis, the following risk factors were utilized in subsequent multivariable logistic regression analysis: region, herd size, weight of purchased gilts, and all-in/all-out practice. Upon multivariate analysis, region, herd size, weight of purchased gilts and all-in/all-out practice were significantly associated with PRV herd seropositivity. These findings indicate that we are facing a serious situation in the prevention and control of pseudorabies. The results could help predict the next outbreak and set out control measures.

No MeSH data available.