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Leiomyosarcoma of the Inferior Vena Cava With Kidney Invasion

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ABSTRACT

Primary leiomyosarcomas of the inferior vena cava (IVC) are rare tumors associated with poor prognosis, and surgical resection with the goal of obtaining negative margins is the gold standard for initial treatment. Tumor characteristics of both extraluminal extension into renal parenchyma and intraluminal extension of the subdiaphragmatic IVC are even less common. The prognosis of vascular leiomyosarcomas is determined by the location and the size of the tumor, as these factors determine the risk of local recurrence and metastasis. We present a case of a 30-year old female incidentally found to have a 14 cm right renal mass and IVC thrombus.

No MeSH data available.


Specimen from right radical nephrectomy, (a) macroscopic and (b) microscopic.
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fig2: Specimen from right radical nephrectomy, (a) macroscopic and (b) microscopic.

Mentions: Final pathologic diagnosis demonstrated a poorly differentiated 15 cm leiomyosarcoma right kidney mass, with extensive venous invasion and tumor necrosis (Fig. 2). The tumor thrombus was also consistent with leiomyosarcoma and measured 7 cm (Fig. 3). The patient has been disease free for 14 months.


Leiomyosarcoma of the Inferior Vena Cava With Kidney Invasion
Specimen from right radical nephrectomy, (a) macroscopic and (b) microscopic.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037210&req=5

fig2: Specimen from right radical nephrectomy, (a) macroscopic and (b) microscopic.
Mentions: Final pathologic diagnosis demonstrated a poorly differentiated 15 cm leiomyosarcoma right kidney mass, with extensive venous invasion and tumor necrosis (Fig. 2). The tumor thrombus was also consistent with leiomyosarcoma and measured 7 cm (Fig. 3). The patient has been disease free for 14 months.

View Article: PubMed Central - PubMed

ABSTRACT

Primary leiomyosarcomas of the inferior vena cava (IVC) are rare tumors associated with poor prognosis, and surgical resection with the goal of obtaining negative margins is the gold standard for initial treatment. Tumor characteristics of both extraluminal extension into renal parenchyma and intraluminal extension of the subdiaphragmatic IVC are even less common. The prognosis of vascular leiomyosarcomas is determined by the location and the size of the tumor, as these factors determine the risk of local recurrence and metastasis. We present a case of a 30-year old female incidentally found to have a 14 cm right renal mass and IVC thrombus.

No MeSH data available.