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Combined liver transplantation and sleeve gastrectomy for end-stage liver disease in a bariatric patient: First European case-report

View Article: PubMed Central - PubMed

ABSTRACT

Non-alcoholic Steatohepatitis is the 3rd indication for liver transplantation.

Obese transplanted patients have higher morbidity and mortality rates.

Bariatric surgery decreases morbidity and mortality in obese patients.

Combined liver transplant and sleeve gastrectomy can be safely performed.

Combined liver transplant and sleeve gastrectomy can be safely performed.

No MeSH data available.


Related in: MedlinePlus

Gastrografin study following sleeve gastrectomy showing absence of leakage.
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fig0005: Gastrografin study following sleeve gastrectomy showing absence of leakage.

Mentions: A methylene blue test was performed to assess the staple line, with no evidence of leakage. Operation time was 8 h and 50 min, requiring transfusions with 2 units of blood and 10 units of fresh frozen plasma. The patient received standard immunosuppression consisting of tacrolimus once daily and everolimus, with the target levels of 5–8 ng/mL and 3–8 ng/mL respectively, as per our centre protocol. The patient had an uneventful recovery, with no evidence of leak from the gastric staple line (Fig. 1) and she was discharged 2 weeks after the combined procedure. Histological findings of the tumour were of a moderately differentiated hepatocellularcarcinoma (Edmonson grade 2), single nodule of 3 × 2.4 × 1.6 cm, on a background of hepatic cirrhosis.


Combined liver transplantation and sleeve gastrectomy for end-stage liver disease in a bariatric patient: First European case-report
Gastrografin study following sleeve gastrectomy showing absence of leakage.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037123&req=5

fig0005: Gastrografin study following sleeve gastrectomy showing absence of leakage.
Mentions: A methylene blue test was performed to assess the staple line, with no evidence of leakage. Operation time was 8 h and 50 min, requiring transfusions with 2 units of blood and 10 units of fresh frozen plasma. The patient received standard immunosuppression consisting of tacrolimus once daily and everolimus, with the target levels of 5–8 ng/mL and 3–8 ng/mL respectively, as per our centre protocol. The patient had an uneventful recovery, with no evidence of leak from the gastric staple line (Fig. 1) and she was discharged 2 weeks after the combined procedure. Histological findings of the tumour were of a moderately differentiated hepatocellularcarcinoma (Edmonson grade 2), single nodule of 3 × 2.4 × 1.6 cm, on a background of hepatic cirrhosis.

View Article: PubMed Central - PubMed

ABSTRACT

Non-alcoholic Steatohepatitis is the 3rd indication for liver transplantation.

Obese transplanted patients have higher morbidity and mortality rates.

Bariatric surgery decreases morbidity and mortality in obese patients.

Combined liver transplant and sleeve gastrectomy can be safely performed.

Combined liver transplant and sleeve gastrectomy can be safely performed.

No MeSH data available.


Related in: MedlinePlus