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Chronic Pulmonary Histoplasmosis and its Clinical Significance: an Under-reported Systemic Fungal Disease

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ABSTRACT

Histoplasmosis is a systemic fungal mycosis caused by Histoplasmacapsulatum. It is a dimorphic fungus which lives as a saprophyte in the environment and occasionally infects immunosuppressed people. H capsulatum is a ubiquitous fungus present throughout the globe and is more common in the temperate world. Human infection with H capsulatum occurs through respiratory route by inhalation of spores present in the air as droplet nuclei. Pulmonary histoplasmosis is difficult to diagnose, more so in the regions where tuberculosis is endemic, and many infected patients remain asymptomatic. In the case of immunosuppression, clinical symptoms of pulmonary infection may be seen along with chances of dissemination. We report a case of chronic pulmonary histoplasmosis in an immunocompetent individual.

No MeSH data available.


Lacto phenol cotton blue (LPCB) mount showing septate hyphae and non-tuberculate, large, thick walled macroconidia
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FIG3: Lacto phenol cotton blue (LPCB) mount showing septate hyphae and non-tuberculate, large, thick walled macroconidia

Mentions: There was no growth at 37° C. Lacto phenol cotton blue (LPCB) mount from the growth revealed the presence of hyphal forms which were septate and possessing prominent, non-tuberculate, large, thick walled macroconidia as shown in Figure 3.


Chronic Pulmonary Histoplasmosis and its Clinical Significance: an Under-reported Systemic Fungal Disease
Lacto phenol cotton blue (LPCB) mount showing septate hyphae and non-tuberculate, large, thick walled macroconidia
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5037059&req=5

FIG3: Lacto phenol cotton blue (LPCB) mount showing septate hyphae and non-tuberculate, large, thick walled macroconidia
Mentions: There was no growth at 37° C. Lacto phenol cotton blue (LPCB) mount from the growth revealed the presence of hyphal forms which were septate and possessing prominent, non-tuberculate, large, thick walled macroconidia as shown in Figure 3.

View Article: PubMed Central - HTML - PubMed

ABSTRACT

Histoplasmosis is a systemic fungal mycosis caused by Histoplasmacapsulatum. It is a dimorphic fungus which lives as a saprophyte in the environment and occasionally infects immunosuppressed people. H capsulatum is a ubiquitous fungus present throughout the globe and is more common in the temperate world. Human infection with H capsulatum occurs through respiratory route by inhalation of spores present in the air as droplet nuclei. Pulmonary histoplasmosis is difficult to diagnose, more so in the regions where tuberculosis is endemic, and many infected patients remain asymptomatic. In the case of immunosuppression, clinical symptoms of pulmonary infection may be seen along with chances of dissemination. We report a case of chronic pulmonary histoplasmosis in an immunocompetent individual.

No MeSH data available.