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Left Ventricular Function Evaluation on a 3T MR Scanner with Parallel RF Transmission Technique: Prospective Comparison of Cine Sequences Acquired before and after Gadolinium Injection

View Article: PubMed Central - PubMed

ABSTRACT

Objectives: To compare cine MR b-TFE sequences acquired before and after gadolinium injection, on a 3T scanner with a parallel RF transmission technique in order to potentially improve scanning time efficiency when evaluating LV function.

Methods: 25 consecutive patients scheduled for a cardiac MRI were prospectively included and had their b-TFE cine sequences acquired before and right after gadobutrol injection. Images were assessed qualitatively (overall image quality, LV edge sharpness, artifacts and LV wall motion) and quantitatively with measurement of LVEF, LV mass, and telediastolic volume and contrast-to-noise ratio (CNR) between the myocardium and the cardiac chamber. Statistical analysis was conducted using a Bayesian paradigm.

Results: No difference was found before or after injection for the LVEF, LV mass and telediastolic volume evaluations. Overall image quality and CNR were significantly lower after injection (estimated coefficient cine after > cine before gadolinium: -1.75 CI = [-3.78;-0.0305], prob(coef>0) = 0% and -0.23 CI = [-0.49;0.04], prob(coef>0) = 4%) respectively), but this decrease did not affect the visual assessment of LV wall motion (cine after > cine before gadolinium: -1.46 CI = [-4.72;1.13], prob(coef>0) = 15%).

Conclusions: In 3T cardiac MRI acquired with parallel RF transmission technique, qualitative and quantitative assessment of LV function can reliably be performed with cine sequences acquired after gadolinium injection, despite a significant decrease in the CNR and the overall image quality.

No MeSH data available.


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Placement of the ROIs in the left ventricular short axis before and after gadolinium injection.
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pone.0163503.g001: Placement of the ROIs in the left ventricular short axis before and after gadolinium injection.

Mentions: Contrast to noise ratio (CNR) was obtained by the signal intensity measurement of the LV cavity and of the adjacent healthy myocardium in the LV short axis, with a circular region of interest (ROI) averaging at least 0.5 cm2 (Fig 1) using the following formula:CNR=LV CAVITY SIGNAL−MYOCARDIUM SIGNALLV CAVITY SD+MYOCARDIUM SD2


Left Ventricular Function Evaluation on a 3T MR Scanner with Parallel RF Transmission Technique: Prospective Comparison of Cine Sequences Acquired before and after Gadolinium Injection
Placement of the ROIs in the left ventricular short axis before and after gadolinium injection.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5036819&req=5

pone.0163503.g001: Placement of the ROIs in the left ventricular short axis before and after gadolinium injection.
Mentions: Contrast to noise ratio (CNR) was obtained by the signal intensity measurement of the LV cavity and of the adjacent healthy myocardium in the LV short axis, with a circular region of interest (ROI) averaging at least 0.5 cm2 (Fig 1) using the following formula:CNR=LV CAVITY SIGNAL−MYOCARDIUM SIGNALLV CAVITY SD+MYOCARDIUM SD2

View Article: PubMed Central - PubMed

ABSTRACT

Objectives: To compare cine MR b-TFE sequences acquired before and after gadolinium injection, on a 3T scanner with a parallel RF transmission technique in order to potentially improve scanning time efficiency when evaluating LV function.

Methods: 25 consecutive patients scheduled for a cardiac MRI were prospectively included and had their b-TFE cine sequences acquired before and right after gadobutrol injection. Images were assessed qualitatively (overall image quality, LV edge sharpness, artifacts and LV wall motion) and quantitatively with measurement of LVEF, LV mass, and telediastolic volume and contrast-to-noise ratio (CNR) between the myocardium and the cardiac chamber. Statistical analysis was conducted using a Bayesian paradigm.

Results: No difference was found before or after injection for the LVEF, LV mass and telediastolic volume evaluations. Overall image quality and CNR were significantly lower after injection (estimated coefficient cine after > cine before gadolinium: -1.75 CI = [-3.78;-0.0305], prob(coef>0) = 0% and -0.23 CI = [-0.49;0.04], prob(coef>0) = 4%) respectively), but this decrease did not affect the visual assessment of LV wall motion (cine after > cine before gadolinium: -1.46 CI = [-4.72;1.13], prob(coef>0) = 15%).

Conclusions: In 3T cardiac MRI acquired with parallel RF transmission technique, qualitative and quantitative assessment of LV function can reliably be performed with cine sequences acquired after gadolinium injection, despite a significant decrease in the CNR and the overall image quality.

No MeSH data available.


Related in: MedlinePlus