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Chronic hypersensitivity pneumonitis

View Article: PubMed Central - PubMed

ABSTRACT

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are proposed for both chronic forms based on exposure, lung auscultation, lung function tests, HRCT findings, bronchoalveolar lavage, and biopsies. Treatment options are limited, but lung transplantation results in greater survival in comparison to idiopathic pulmonary fibrosis. Randomized trials with new antifibrotic agents are necessary.

No MeSH data available.


Related in: MedlinePlus

Chronic fibrosing HSP.Notes: Male, 64 years of age, ex-smoker. dyspnea and cough for 2 years. Exposure to molds at home. HRCT-reticular pattern predominant in upper lobes, with peribronchovascular distribution, peripheral reticular pattern with honeycombing, asymmetric in lower lobes (A) and (B). Surgical lung biopsy-centered airway fibrosis (C) with chronic inflammatory infiltrate (D) and organizing foci in airways (E).Abbreviations: HSP, hypersensitivity pneumonitis; HRCT, high-resolution computed tomography.
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f3-jaa-9-171: Chronic fibrosing HSP.Notes: Male, 64 years of age, ex-smoker. dyspnea and cough for 2 years. Exposure to molds at home. HRCT-reticular pattern predominant in upper lobes, with peribronchovascular distribution, peripheral reticular pattern with honeycombing, asymmetric in lower lobes (A) and (B). Surgical lung biopsy-centered airway fibrosis (C) with chronic inflammatory infiltrate (D) and organizing foci in airways (E).Abbreviations: HSP, hypersensitivity pneumonitis; HRCT, high-resolution computed tomography.

Mentions: Findings on HRCT and lung biopsy in nonfibrosing and fibrosing chronic HP are shown in Figures 2 and 3, respectively.


Chronic hypersensitivity pneumonitis
Chronic fibrosing HSP.Notes: Male, 64 years of age, ex-smoker. dyspnea and cough for 2 years. Exposure to molds at home. HRCT-reticular pattern predominant in upper lobes, with peribronchovascular distribution, peripheral reticular pattern with honeycombing, asymmetric in lower lobes (A) and (B). Surgical lung biopsy-centered airway fibrosis (C) with chronic inflammatory infiltrate (D) and organizing foci in airways (E).Abbreviations: HSP, hypersensitivity pneumonitis; HRCT, high-resolution computed tomography.
© Copyright Policy
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5036552&req=5

f3-jaa-9-171: Chronic fibrosing HSP.Notes: Male, 64 years of age, ex-smoker. dyspnea and cough for 2 years. Exposure to molds at home. HRCT-reticular pattern predominant in upper lobes, with peribronchovascular distribution, peripheral reticular pattern with honeycombing, asymmetric in lower lobes (A) and (B). Surgical lung biopsy-centered airway fibrosis (C) with chronic inflammatory infiltrate (D) and organizing foci in airways (E).Abbreviations: HSP, hypersensitivity pneumonitis; HRCT, high-resolution computed tomography.
Mentions: Findings on HRCT and lung biopsy in nonfibrosing and fibrosing chronic HP are shown in Figures 2 and 3, respectively.

View Article: PubMed Central - PubMed

ABSTRACT

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are proposed for both chronic forms based on exposure, lung auscultation, lung function tests, HRCT findings, bronchoalveolar lavage, and biopsies. Treatment options are limited, but lung transplantation results in greater survival in comparison to idiopathic pulmonary fibrosis. Randomized trials with new antifibrotic agents are necessary.

No MeSH data available.


Related in: MedlinePlus