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Chronic hypersensitivity pneumonitis

View Article: PubMed Central - PubMed

ABSTRACT

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are proposed for both chronic forms based on exposure, lung auscultation, lung function tests, HRCT findings, bronchoalveolar lavage, and biopsies. Treatment options are limited, but lung transplantation results in greater survival in comparison to idiopathic pulmonary fibrosis. Randomized trials with new antifibrotic agents are necessary.

No MeSH data available.


Related in: MedlinePlus

Chronic HSP caused by feather pillows.Notes: Male, 67 years of age, nonsmoker, asymptomatic, but with progressive ILD; on HRCT since 2009. Use of feather pillows for 8 years. FVC =3.02 L (70%), DLCO =12.3 mL/min/mmHg (74% of predicted). Videothoracoscopic biopsy from three lobes on the right side.Abbreviations: HSP, hypersensitivity pneumonitis; ILD, interstitial lung disease, HRCT, high-resolution computed tomography; FVC, forced vital capacity; DLACO, diffusing capacity for carbon monoxide.
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f1-jaa-9-171: Chronic HSP caused by feather pillows.Notes: Male, 67 years of age, nonsmoker, asymptomatic, but with progressive ILD; on HRCT since 2009. Use of feather pillows for 8 years. FVC =3.02 L (70%), DLCO =12.3 mL/min/mmHg (74% of predicted). Videothoracoscopic biopsy from three lobes on the right side.Abbreviations: HSP, hypersensitivity pneumonitis; ILD, interstitial lung disease, HRCT, high-resolution computed tomography; FVC, forced vital capacity; DLACO, diffusing capacity for carbon monoxide.

Mentions: A case of fibrotic HSP submitted to surgical lung biopsy, with fragments retrieved from three lobes at right, is shown in Figure 1. The diversity of pathologic findings is illustrated in this case.


Chronic hypersensitivity pneumonitis
Chronic HSP caused by feather pillows.Notes: Male, 67 years of age, nonsmoker, asymptomatic, but with progressive ILD; on HRCT since 2009. Use of feather pillows for 8 years. FVC =3.02 L (70%), DLCO =12.3 mL/min/mmHg (74% of predicted). Videothoracoscopic biopsy from three lobes on the right side.Abbreviations: HSP, hypersensitivity pneumonitis; ILD, interstitial lung disease, HRCT, high-resolution computed tomography; FVC, forced vital capacity; DLACO, diffusing capacity for carbon monoxide.
© Copyright Policy
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5036552&req=5

f1-jaa-9-171: Chronic HSP caused by feather pillows.Notes: Male, 67 years of age, nonsmoker, asymptomatic, but with progressive ILD; on HRCT since 2009. Use of feather pillows for 8 years. FVC =3.02 L (70%), DLCO =12.3 mL/min/mmHg (74% of predicted). Videothoracoscopic biopsy from three lobes on the right side.Abbreviations: HSP, hypersensitivity pneumonitis; ILD, interstitial lung disease, HRCT, high-resolution computed tomography; FVC, forced vital capacity; DLACO, diffusing capacity for carbon monoxide.
Mentions: A case of fibrotic HSP submitted to surgical lung biopsy, with fragments retrieved from three lobes at right, is shown in Figure 1. The diversity of pathologic findings is illustrated in this case.

View Article: PubMed Central - PubMed

ABSTRACT

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are proposed for both chronic forms based on exposure, lung auscultation, lung function tests, HRCT findings, bronchoalveolar lavage, and biopsies. Treatment options are limited, but lung transplantation results in greater survival in comparison to idiopathic pulmonary fibrosis. Randomized trials with new antifibrotic agents are necessary.

No MeSH data available.


Related in: MedlinePlus