Limits...
Clinical Consideration of Treatment to Ablate Uterine Fibroids with Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MRgFUS): Sonalleve

View Article: PubMed Central - PubMed

ABSTRACT

Objectives: Magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS) is a newly emerging non-invasive technique for the treatment of uterine fibroids. The purpose of this study is to review the clinical impact of MRgFUS.

Methods: This study examined 157 patients. The high intensity focused ultrasound (HIFU) utilized in this study was Philips Achieva 1.5 Tesla MR (Philips Healthcare, Best, the Netherlands) and Sonalleve HIFU system. The patients were followed in post-operative Month 1, Month 3, and Month 6 to investigate any change. Then, these were further classified according to the use of uterine stimulant (oxytocin) in parallel, Funaki Type of uterine fibroid, HIFU intensity, and non-perfused volume (NPV) ratio.

Results: When the uterine stimulant was utilized, the HIFU intensity was measured at significantly lower levels, compared with the group not using uterine stimulant, and treatment duration was significantly. The NPV ratio was found significantly higher in the group using uterine stimulant. Concerning the correlation between Funaki Type of uterine fibroid and average sonication power, it was found that the closer to Type I, the lower the sonication power, the shorter the treatment duration, and the higher the NPV ratio significantly.

Conclusions: In this study, it was found that the lower the Funaki Types of uterine fibroids, and the higher the NPV ratio immediately after the operation, the larger the uterine fibroid volume decrease and SSS change were. Also, if uterine stimulant was used in parallel in treatment, treatment duration and HIFU intensity could become shorter and lower.

No MeSH data available.


Related in: MedlinePlus

Correlation between non-perfused volume (NPV) ratio, average sonication power and Funaki type of uterine fibroids after magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS). *The average sonication power was classified by 1: <100, 2 :100-130, 3 :130-160, 4: >160. Pearson correlation coefficient and Spearman correlation coefficient were 0.311 and 0.300 between the average sonication power and Funaki type of uterine fibroid, -0.344 and -0.320 between the NPV ratio and Funaki type of uterine fibroid in MRgFUS;both were statistically significant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC5016510&req=5

Figure 4: Correlation between non-perfused volume (NPV) ratio, average sonication power and Funaki type of uterine fibroids after magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS). *The average sonication power was classified by 1: <100, 2 :100-130, 3 :130-160, 4: >160. Pearson correlation coefficient and Spearman correlation coefficient were 0.311 and 0.300 between the average sonication power and Funaki type of uterine fibroid, -0.344 and -0.320 between the NPV ratio and Funaki type of uterine fibroid in MRgFUS;both were statistically significant.

Mentions: Concerning the correlation between Funaki type of uterine fibroid and average sonication power, it was found that the closer to Type I, the lower the sonication power was with statistical significance (spearman correlation coefficient 0.305). Regarding the correlation between treatment hours and NPV ratio, shorter treatment hours and higher NPV ratio were observed with statistical significance. The spearman correlation coefficient was 0.185, and correlation coefficient was -0.320, respectively (Table 5; Fig. 4). According to Funaki type of uterine fibroid, Type I and Type II showed significantly lower pre-operative SSS levels and the SSS change ratios were also significantly lower in all of the post-operative Month 1, Month 3, and Month 6. However, no correlation was found between Funaki type of uterine fibroid and uterine fibroid volume change, complication existence or re-intervention.


Clinical Consideration of Treatment to Ablate Uterine Fibroids with Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MRgFUS): Sonalleve
Correlation between non-perfused volume (NPV) ratio, average sonication power and Funaki type of uterine fibroids after magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS). *The average sonication power was classified by 1: <100, 2 :100-130, 3 :130-160, 4: >160. Pearson correlation coefficient and Spearman correlation coefficient were 0.311 and 0.300 between the average sonication power and Funaki type of uterine fibroid, -0.344 and -0.320 between the NPV ratio and Funaki type of uterine fibroid in MRgFUS;both were statistically significant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC5016510&req=5

Figure 4: Correlation between non-perfused volume (NPV) ratio, average sonication power and Funaki type of uterine fibroids after magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS). *The average sonication power was classified by 1: <100, 2 :100-130, 3 :130-160, 4: >160. Pearson correlation coefficient and Spearman correlation coefficient were 0.311 and 0.300 between the average sonication power and Funaki type of uterine fibroid, -0.344 and -0.320 between the NPV ratio and Funaki type of uterine fibroid in MRgFUS;both were statistically significant.
Mentions: Concerning the correlation between Funaki type of uterine fibroid and average sonication power, it was found that the closer to Type I, the lower the sonication power was with statistical significance (spearman correlation coefficient 0.305). Regarding the correlation between treatment hours and NPV ratio, shorter treatment hours and higher NPV ratio were observed with statistical significance. The spearman correlation coefficient was 0.185, and correlation coefficient was -0.320, respectively (Table 5; Fig. 4). According to Funaki type of uterine fibroid, Type I and Type II showed significantly lower pre-operative SSS levels and the SSS change ratios were also significantly lower in all of the post-operative Month 1, Month 3, and Month 6. However, no correlation was found between Funaki type of uterine fibroid and uterine fibroid volume change, complication existence or re-intervention.

View Article: PubMed Central - PubMed

ABSTRACT

Objectives: Magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS) is a newly emerging non-invasive technique for the treatment of uterine fibroids. The purpose of this study is to review the clinical impact of MRgFUS.

Methods: This study examined 157 patients. The high intensity focused ultrasound (HIFU) utilized in this study was Philips Achieva 1.5 Tesla MR (Philips Healthcare, Best, the Netherlands) and Sonalleve HIFU system. The patients were followed in post-operative Month 1, Month 3, and Month 6 to investigate any change. Then, these were further classified according to the use of uterine stimulant (oxytocin) in parallel, Funaki Type of uterine fibroid, HIFU intensity, and non-perfused volume (NPV) ratio.

Results: When the uterine stimulant was utilized, the HIFU intensity was measured at significantly lower levels, compared with the group not using uterine stimulant, and treatment duration was significantly. The NPV ratio was found significantly higher in the group using uterine stimulant. Concerning the correlation between Funaki Type of uterine fibroid and average sonication power, it was found that the closer to Type I, the lower the sonication power, the shorter the treatment duration, and the higher the NPV ratio significantly.

Conclusions: In this study, it was found that the lower the Funaki Types of uterine fibroids, and the higher the NPV ratio immediately after the operation, the larger the uterine fibroid volume decrease and SSS change were. Also, if uterine stimulant was used in parallel in treatment, treatment duration and HIFU intensity could become shorter and lower.

No MeSH data available.


Related in: MedlinePlus