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Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis

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ABSTRACT

Diabetes is one of the most important epidemic diseases of this century and the number of people with diabetes has more than doubled over the past three decades. Our aim was to estimate the prevalence of diabetes in the adult Brazilian population and analyze the trends for the last three decades through a systematic review with meta-analysis. This review included observational studies published between 1980 and 2015, which were independently identified by two reviewers in five databases. Random effect models were used to estimate the prevalence and trends of diabetes. In total, 50 articles were included in this review. Three different patterns for diabetes diagnosis were identified: self-report (36 studies), fasting glucose (7 studies), and complex diagnosis (fasting glucose, oral glucose tolerance test, and self-report; 7 studies). The prevalence of diabetes was 5.6 % (95 % CI 5.0–6.3; I2 = 100 %) by self-report, 6.6 % (95 % CI 4.8–8.9; I2 = 94 %) by fasting glucose, and 11.9 % (95 % CI 7.7–17.8 I2 = 100 %) by complex diagnosis. In trend analyses, we observed an increase in the prevalence of diabetes over time. The biggest increase was detected in studies using complex diagnosis: 7.4 % (95 % CI 7.1–7.7) in the 1980s to 15.7 % (95 % CI 9.8–24.3) in the 2010s. In conclusion, despite high heterogeneity, this study observed a high prevalence of diabetes in Brazilian adults over time and with a progressive increase in the last 35 years.

Electronic supplementary material: The online version of this article (doi:10.1186/s13098-016-0181-1) contains supplementary material, which is available to authorized users.

No MeSH data available.


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Forest plot representing diabetes prevalence rates by self-reported diagnosis and decades
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Fig1: Forest plot representing diabetes prevalence rates by self-reported diagnosis and decades

Mentions: The search retrieved 2522 articles from January 1980 to December 2015, of which 496 were duplicates and were excluded. Additional 1909 articles were removed based on title and abstracts; 117 full-text articles were assessed for eligibility, of which 40 met all the inclusion criteria. Manual search retrieved other ten articles, totalizing 50 studies (1,393,637 individuals) that were included in the final analyses. The flowchart of studies selection is presented in Fig. 1. Three different patterns for diabetes diagnosis were identified: self-report, fasting glucose, and complex diagnosis [e.g. fasting glucose + oral glucose tolerance test (OGTT) + self-report]. The characteristics of the included studies by diagnosis criteria and method of assessment are described in Table 1.Fig. 1


Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis
Forest plot representing diabetes prevalence rates by self-reported diagnosis and decades
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC5015260&req=5

Fig1: Forest plot representing diabetes prevalence rates by self-reported diagnosis and decades
Mentions: The search retrieved 2522 articles from January 1980 to December 2015, of which 496 were duplicates and were excluded. Additional 1909 articles were removed based on title and abstracts; 117 full-text articles were assessed for eligibility, of which 40 met all the inclusion criteria. Manual search retrieved other ten articles, totalizing 50 studies (1,393,637 individuals) that were included in the final analyses. The flowchart of studies selection is presented in Fig. 1. Three different patterns for diabetes diagnosis were identified: self-report, fasting glucose, and complex diagnosis [e.g. fasting glucose + oral glucose tolerance test (OGTT) + self-report]. The characteristics of the included studies by diagnosis criteria and method of assessment are described in Table 1.Fig. 1

View Article: PubMed Central - PubMed

ABSTRACT

Diabetes is one of the most important epidemic diseases of this century and the number of people with diabetes has more than doubled over the past three decades. Our aim was to estimate the prevalence of diabetes in the adult Brazilian population and analyze the trends for the last three decades through a systematic review with meta-analysis. This review included observational studies published between 1980 and 2015, which were independently identified by two reviewers in five databases. Random effect models were used to estimate the prevalence and trends of diabetes. In total, 50 articles were included in this review. Three different patterns for diabetes diagnosis were identified: self-report (36 studies), fasting glucose (7 studies), and complex diagnosis (fasting glucose, oral glucose tolerance test, and self-report; 7 studies). The prevalence of diabetes was 5.6 % (95 % CI 5.0–6.3; I2 = 100 %) by self-report, 6.6 % (95 % CI 4.8–8.9; I2 = 94 %) by fasting glucose, and 11.9 % (95 % CI 7.7–17.8 I2 = 100 %) by complex diagnosis. In trend analyses, we observed an increase in the prevalence of diabetes over time. The biggest increase was detected in studies using complex diagnosis: 7.4 % (95 % CI 7.1–7.7) in the 1980s to 15.7 % (95 % CI 9.8–24.3) in the 2010s. In conclusion, despite high heterogeneity, this study observed a high prevalence of diabetes in Brazilian adults over time and with a progressive increase in the last 35 years.

Electronic supplementary material: The online version of this article (doi:10.1186/s13098-016-0181-1) contains supplementary material, which is available to authorized users.

No MeSH data available.


Related in: MedlinePlus