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Association between pregnancy and adnexal torsion

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ABSTRACT

The purpose of this study was to determine the effect of pregnancy on adnexal torsion (AT). We conducted a matched case-control study using the Korean Health Insurance Review and Assessment Service–National Inpatients Sample (HIRA-NIS) from 2009 to 2011. AT patients were defined as women with both a diagnostic code (N835) and a surgical code for AT. The AT patients were randomly matched 1:4 with women without AT by age and year of claim. In total, 545 AT cases and 2180 controls were enrolled from a total of 1,843,451 women. After adjustment for such covariates as age, pregnancy was found to be associated with a lower rate of AT (adjusted odds ratio 0.314, 95% confidence interval [CI] 0.237–0.416, P value <0.01) and ovarian hyperstimulation syndrome was associated with a higher rate of AT (adjusted odds ratio 20.091, 95% CI 3.607–111.908, P value <0.01). We found that pregnancy is a negative risk factor for AT. However, a further study is needed to elucidate the mechanisms underlying these results.

No MeSH data available.


Flowchart about the selection procedure from the HIRA sample 2009 to 2011.
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Figure 1: Flowchart about the selection procedure from the HIRA sample 2009 to 2011.

Mentions: We selected a sample of 1,843,451 women from the HIRA-NIS database of ∼3 million individuals in 2009 to 2011. Among the sampled women, there were 545 cases of AT; 2180 controls were matched to these cases by age and sampling weights, with a match ratio of 1:4. A flowchart in Fig. 1 presents the process of patients’ inclusion. There was no recurrent adnexal torsion episode in AT cases. Demographic characteristics for cases and controls are presented as Table 1. The mean age was 33.79 ± 13.39 for cases and 33.84 ± 13.55 for controls.


Association between pregnancy and adnexal torsion
Flowchart about the selection procedure from the HIRA sample 2009 to 2011.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4998453&req=5

Figure 1: Flowchart about the selection procedure from the HIRA sample 2009 to 2011.
Mentions: We selected a sample of 1,843,451 women from the HIRA-NIS database of ∼3 million individuals in 2009 to 2011. Among the sampled women, there were 545 cases of AT; 2180 controls were matched to these cases by age and sampling weights, with a match ratio of 1:4. A flowchart in Fig. 1 presents the process of patients’ inclusion. There was no recurrent adnexal torsion episode in AT cases. Demographic characteristics for cases and controls are presented as Table 1. The mean age was 33.79 ± 13.39 for cases and 33.84 ± 13.55 for controls.

View Article: PubMed Central - PubMed

ABSTRACT

The purpose of this study was to determine the effect of pregnancy on adnexal torsion (AT). We conducted a matched case-control study using the Korean Health Insurance Review and Assessment Service–National Inpatients Sample (HIRA-NIS) from 2009 to 2011. AT patients were defined as women with both a diagnostic code (N835) and a surgical code for AT. The AT patients were randomly matched 1:4 with women without AT by age and year of claim. In total, 545 AT cases and 2180 controls were enrolled from a total of 1,843,451 women. After adjustment for such covariates as age, pregnancy was found to be associated with a lower rate of AT (adjusted odds ratio 0.314, 95% confidence interval [CI] 0.237–0.416, P value <0.01) and ovarian hyperstimulation syndrome was associated with a higher rate of AT (adjusted odds ratio 20.091, 95% CI 3.607–111.908, P value <0.01). We found that pregnancy is a negative risk factor for AT. However, a further study is needed to elucidate the mechanisms underlying these results.

No MeSH data available.