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Reduced central line infection rates in children with leukemia following caregiver training

View Article: PubMed Central - PubMed

ABSTRACT

Infections are a leading cause of morbidity and mortality in children with acute leukemia. Central-line (CL) devices increase this population's risk of serious infections.

Within the context of a quality improvement (QI) project, we tested the effect of caregiver education on CL management on the CL-associated bloodstream infection (CLABSI) rate among children with acute leukemia seen at a large referral center in Italy. The intervention consisted of 9 in-person sessions for education and practice using mannequins and children.

One hundred and twenty caregivers agreed to participate in the initiative. One hundred and five (87.5%) completed the training, 5 (4.1%) withdrew after the first session, and 10 (8.3%) withdrew during practical sessions. After educational intervention, the overall CLABSI rate was reduced by 46% (from 6.86 to 3.70/1000 CL-days). CLABSI rate was lower in children whose caregivers completed the training (1.74/1000 CL-days, 95% CI 0.43–6.94) compared with those who did not receive any training (12.2/1000 CL-days, 95% CI 7.08–21.0, P < 0.05) or were in-training (3.96/1000 CL-days, 95% CI 1.98–7.91) at the time of infection.

Caregiver training in CL management, applied within a multifaceted QI approach, reduced the rate of CLABSI in children with acute leukemia. Specific training and active involvement of caregivers in CL management may be effective to reduce CLABSI in high-risk children.

No MeSH data available.


Related in: MedlinePlus

CLABSI rates according to the level of family training. CLABSI = central-line associated blood stream infection.
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Figure 2: CLABSI rates according to the level of family training. CLABSI = central-line associated blood stream infection.

Mentions: Cumulative CLABSI rate among patients whose caregivers were fully trained at the time of infection was lower (1.74/1000 CL-days) than those whose caregivers were not trained at the time of infection (12.2/1000 CL-days, P < 0.05). An intermediate CLABSI rate was observed among children managed by in training caregivers at the time of infection (3.96/1000 CL-days). Fig. 2 reports the raw cumulative rates with 95% CI.


Reduced central line infection rates in children with leukemia following caregiver training
CLABSI rates according to the level of family training. CLABSI = central-line associated blood stream infection.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4998326&req=5

Figure 2: CLABSI rates according to the level of family training. CLABSI = central-line associated blood stream infection.
Mentions: Cumulative CLABSI rate among patients whose caregivers were fully trained at the time of infection was lower (1.74/1000 CL-days) than those whose caregivers were not trained at the time of infection (12.2/1000 CL-days, P < 0.05). An intermediate CLABSI rate was observed among children managed by in training caregivers at the time of infection (3.96/1000 CL-days). Fig. 2 reports the raw cumulative rates with 95% CI.

View Article: PubMed Central - PubMed

ABSTRACT

Infections are a leading cause of morbidity and mortality in children with acute leukemia. Central-line (CL) devices increase this population's risk of serious infections.

Within the context of a quality improvement (QI) project, we tested the effect of caregiver education on CL management on the CL-associated bloodstream infection (CLABSI) rate among children with acute leukemia seen at a large referral center in Italy. The intervention consisted of 9 in-person sessions for education and practice using mannequins and children.

One hundred and twenty caregivers agreed to participate in the initiative. One hundred and five (87.5%) completed the training, 5 (4.1%) withdrew after the first session, and 10 (8.3%) withdrew during practical sessions. After educational intervention, the overall CLABSI rate was reduced by 46% (from 6.86 to 3.70/1000 CL-days). CLABSI rate was lower in children whose caregivers completed the training (1.74/1000 CL-days, 95% CI 0.43&ndash;6.94) compared with those who did not receive any training (12.2/1000 CL-days, 95% CI 7.08&ndash;21.0, P&#8202;&lt;&#8202;0.05) or were in-training (3.96/1000 CL-days, 95% CI 1.98&ndash;7.91) at the time of infection.

Caregiver training in CL management, applied within a multifaceted QI approach, reduced the rate of CLABSI in children with acute leukemia. Specific training and active involvement of caregivers in CL management may be effective to reduce CLABSI in high-risk children.

No MeSH data available.


Related in: MedlinePlus