Limits...
Pulmonary chondroma: A clinicopathological study of 29 cases and a review of the literature

View Article: PubMed Central - PubMed

ABSTRACT

The present retrospective study was designed to review the clinicopathological features and outcome of surgical treatment of pulmonary chondroma, and to accumulate data for the clinical diagnosis and therapy. The clinicopathological data from 29 patients, aged between 38- and 78-years-old, with pulmonary chondroma who underwent surgical operation between July 2003 and June 2015 were reviewed. Of these patients, 18 exhibited no clinical symptoms, 7 were characterized by coughing, hemoptysis, shortness of breath and other symptoms and only 3 patients exhibited chest pain as the predominant symptom. The average size of the neoplasms was 3.6 cm. All patients were pathologically diagnosed. Operative time was 126±22 min, the mean intraoperative blood loss was 82±23 ml and the drainage duration was 3.1±1.8 days. A total of 6 postoperative complications were noted. The patients were followed-up for 2–135 months. A total of 23 patients were alive without recurrence, 4 patients succumbed to mortality, 2 patients were lost at follow-up. Pulmonary chondroma is a rare benign tumor of the lung. The clinical symptoms were concealed and often misdiagnosed as a tuberculosis tumor, hamartoma, peripheral lung cancer or a single metastatic tumor. Complete resection was the best treatment providing patients with a good prognosis. After definite diagnosis, it is necessary to exclude Carney's triad.

No MeSH data available.


Related in: MedlinePlus

Images of the resected mass. (A) Patients with pulmonary chondroma underwent lobectomy intraoperatively. (B) The mass was pale and translucent, hard, and lobulated on the lateral section.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4998203&req=5

f2-mco-0-0-945: Images of the resected mass. (A) Patients with pulmonary chondroma underwent lobectomy intraoperatively. (B) The mass was pale and translucent, hard, and lobulated on the lateral section.

Mentions: A total of 11 patients underwent lobectomy (Fig. 2), 17 patients underwent segmentectomy and 1 patient used lump stripping. They were postoperatively pathologically diagnosed as pulmonary chondroma (Fig. 3). All the lymph nodes were reactive hyperplasia. Carney's triad was excluded by abdominal magnetic resonance imaging (MRI) and gastroscopy. No mortality occurred during surgery. The operative duration ranged between 48 and 215 min (mean, 126±22 min). The estimated blood loss ranged between 5 and 350 ml (mean, 82±23 ml). Additionally, no patient required a blood transfusion. All patients, with the exception of 5 patients, had an uneventful postoperative course (82.8%). Of the five complications, two were postoperative encapsulated pleural effusion and three were pulmonary infection. These 5 patients recovered well following percutaneous catheter drainage by CT-guided and anti-infection therapy. The drainage duration ranged between 2 and 8 days (mean, 3.1±1.8 days) and the postoperative hospital duration ranged between 4 and 13 days (mean, 4.0±2.1 days). Patients were followed-up between 2 and 135 months. During follow-up, 23 patients were alive without recurrence, 1 patient succumbed to esophageal cancer after 19 months post-surgery, 3 patients succumbed to other diseases. A total of 2 patients were lost during follow-up.


Pulmonary chondroma: A clinicopathological study of 29 cases and a review of the literature
Images of the resected mass. (A) Patients with pulmonary chondroma underwent lobectomy intraoperatively. (B) The mass was pale and translucent, hard, and lobulated on the lateral section.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4998203&req=5

f2-mco-0-0-945: Images of the resected mass. (A) Patients with pulmonary chondroma underwent lobectomy intraoperatively. (B) The mass was pale and translucent, hard, and lobulated on the lateral section.
Mentions: A total of 11 patients underwent lobectomy (Fig. 2), 17 patients underwent segmentectomy and 1 patient used lump stripping. They were postoperatively pathologically diagnosed as pulmonary chondroma (Fig. 3). All the lymph nodes were reactive hyperplasia. Carney's triad was excluded by abdominal magnetic resonance imaging (MRI) and gastroscopy. No mortality occurred during surgery. The operative duration ranged between 48 and 215 min (mean, 126±22 min). The estimated blood loss ranged between 5 and 350 ml (mean, 82±23 ml). Additionally, no patient required a blood transfusion. All patients, with the exception of 5 patients, had an uneventful postoperative course (82.8%). Of the five complications, two were postoperative encapsulated pleural effusion and three were pulmonary infection. These 5 patients recovered well following percutaneous catheter drainage by CT-guided and anti-infection therapy. The drainage duration ranged between 2 and 8 days (mean, 3.1±1.8 days) and the postoperative hospital duration ranged between 4 and 13 days (mean, 4.0±2.1 days). Patients were followed-up between 2 and 135 months. During follow-up, 23 patients were alive without recurrence, 1 patient succumbed to esophageal cancer after 19 months post-surgery, 3 patients succumbed to other diseases. A total of 2 patients were lost during follow-up.

View Article: PubMed Central - PubMed

ABSTRACT

The present retrospective study was designed to review the clinicopathological features and outcome of surgical treatment of pulmonary chondroma, and to accumulate data for the clinical diagnosis and therapy. The clinicopathological data from 29 patients, aged between 38- and 78-years-old, with pulmonary chondroma who underwent surgical operation between July 2003 and June 2015 were reviewed. Of these patients, 18 exhibited no clinical symptoms, 7 were characterized by coughing, hemoptysis, shortness of breath and other symptoms and only 3 patients exhibited chest pain as the predominant symptom. The average size of the neoplasms was 3.6 cm. All patients were pathologically diagnosed. Operative time was 126±22 min, the mean intraoperative blood loss was 82±23 ml and the drainage duration was 3.1±1.8 days. A total of 6 postoperative complications were noted. The patients were followed-up for 2–135 months. A total of 23 patients were alive without recurrence, 4 patients succumbed to mortality, 2 patients were lost at follow-up. Pulmonary chondroma is a rare benign tumor of the lung. The clinical symptoms were concealed and often misdiagnosed as a tuberculosis tumor, hamartoma, peripheral lung cancer or a single metastatic tumor. Complete resection was the best treatment providing patients with a good prognosis. After definite diagnosis, it is necessary to exclude Carney's triad.

No MeSH data available.


Related in: MedlinePlus