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Control of Risk Factors for Cardiovascular Disease among Multinational Patient Population in the Arabian Gulf

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ABSTRACT

We evaluated the control of cardiovascular disease (CVD) risk factors among patients with atherosclerotic cardiovascular disease (ASCVD) in the Centralized Pan-Middle East Survey on the undertreatment of hypercholesterolaemia (CEPHEUS) in the Arabian Gulf. Of the 4398 enrolled patients, overall mean age was 57 ± 11 years, 60% were males, 13% were smokers, 76% had diabetes, 71% had metabolic syndrome and 78% had very high ASCVD risk status. The proportion of subjects with body mass index <25 kg/m2, HbA1c <7% (in diabetics), low-density lipoprotein cholesterol (LDL-C) <2.6 mmol/L (100 mg/dL) and <1.8 mmol/L (70 mg/dL) for high and very high ASCVD risk cohorts, respectively and controlled blood pressure (<140/90 mmHg) was 14, 26, 31% and 60%, respectively. Only 1.4% of the participants had all of their CVD risk factors controlled with significant differences among the countries (P < .001). CVD risk goal attainment rates were significantly lower in those with very high ASCVD risk compared with those with high ASCVD risk status (P < .001). Females were also, generally, less likely to attain goals when compared with males (P < .001).

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Overall goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high atherosclerotic cardiovascular disease (ASCVD)risk patients stratified by gender in the Arabian Gulf (N = 3431).Abbreviations: BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure.Criteria for ASCVD risk status was adapted from the National Lipid Association criteria22 for atherosclerotic cardiovascular disease. Highrisk group included patients with 3 major ASCVD risk factors, diabetes mellitus (type 1 or 2) with 0–1 major ASCVD risk factor and LDLC190 mg/dL (5.02 mmol/L) (severe hypercholesterolemia). Very high ASCVD risk group included coronary heart disease, peripheral arterydisease, cerebrovascular disease and diabetes mellitus with 2 other major ASCVD risk factors.CVD risk factor goal attainments were no smoking, BMI <25 kg/m2, HbA1c <7% and LDL-C for the very ASCVD risk patients was LDL-C< 70 mg/dL (1.8 mmol/L).BP goals were adapted from the new JNC-8 2014 Hypertension Guideline Management Algorithm.23 BP goals for those without diabetesmellitus (DM) and 60 years and those <60 years were <150/90 mmHg and <140/90 mmHg, respectively. For those with DM irrespective ofage, the BP goal was <140/90 mmHg.
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Figure 2: Overall goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high atherosclerotic cardiovascular disease (ASCVD)risk patients stratified by gender in the Arabian Gulf (N = 3431).Abbreviations: BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure.Criteria for ASCVD risk status was adapted from the National Lipid Association criteria22 for atherosclerotic cardiovascular disease. Highrisk group included patients with 3 major ASCVD risk factors, diabetes mellitus (type 1 or 2) with 0–1 major ASCVD risk factor and LDLC190 mg/dL (5.02 mmol/L) (severe hypercholesterolemia). Very high ASCVD risk group included coronary heart disease, peripheral arterydisease, cerebrovascular disease and diabetes mellitus with 2 other major ASCVD risk factors.CVD risk factor goal attainments were no smoking, BMI <25 kg/m2, HbA1c <7% and LDL-C for the very ASCVD risk patients was LDL-C< 70 mg/dL (1.8 mmol/L).BP goals were adapted from the new JNC-8 2014 Hypertension Guideline Management Algorithm.23 BP goals for those without diabetesmellitus (DM) and 60 years and those <60 years were <150/90 mmHg and <140/90 mmHg, respectively. For those with DM irrespective ofage, the BP goal was <140/90 mmHg.

Mentions: 2 summarizes goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high ASCVD risk patients stratified by gender. Males were more likely to attain BMI <25 kg/m2 (18 vs. 9%; P < .001), LDL-C (30 vs. 20%; P < .001) and BP (58 vs. 53%; P < .001) goal achievements when compared with females. Females on the other hand were less likely to smoke (98 vs. 81%; P < .001).


Control of Risk Factors for Cardiovascular Disease among Multinational Patient Population in the Arabian Gulf
Overall goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high atherosclerotic cardiovascular disease (ASCVD)risk patients stratified by gender in the Arabian Gulf (N = 3431).Abbreviations: BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure.Criteria for ASCVD risk status was adapted from the National Lipid Association criteria22 for atherosclerotic cardiovascular disease. Highrisk group included patients with 3 major ASCVD risk factors, diabetes mellitus (type 1 or 2) with 0–1 major ASCVD risk factor and LDLC190 mg/dL (5.02 mmol/L) (severe hypercholesterolemia). Very high ASCVD risk group included coronary heart disease, peripheral arterydisease, cerebrovascular disease and diabetes mellitus with 2 other major ASCVD risk factors.CVD risk factor goal attainments were no smoking, BMI <25 kg/m2, HbA1c <7% and LDL-C for the very ASCVD risk patients was LDL-C< 70 mg/dL (1.8 mmol/L).BP goals were adapted from the new JNC-8 2014 Hypertension Guideline Management Algorithm.23 BP goals for those without diabetesmellitus (DM) and 60 years and those <60 years were <150/90 mmHg and <140/90 mmHg, respectively. For those with DM irrespective ofage, the BP goal was <140/90 mmHg.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4997936&req=5

Figure 2: Overall goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high atherosclerotic cardiovascular disease (ASCVD)risk patients stratified by gender in the Arabian Gulf (N = 3431).Abbreviations: BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure.Criteria for ASCVD risk status was adapted from the National Lipid Association criteria22 for atherosclerotic cardiovascular disease. Highrisk group included patients with 3 major ASCVD risk factors, diabetes mellitus (type 1 or 2) with 0–1 major ASCVD risk factor and LDLC190 mg/dL (5.02 mmol/L) (severe hypercholesterolemia). Very high ASCVD risk group included coronary heart disease, peripheral arterydisease, cerebrovascular disease and diabetes mellitus with 2 other major ASCVD risk factors.CVD risk factor goal attainments were no smoking, BMI <25 kg/m2, HbA1c <7% and LDL-C for the very ASCVD risk patients was LDL-C< 70 mg/dL (1.8 mmol/L).BP goals were adapted from the new JNC-8 2014 Hypertension Guideline Management Algorithm.23 BP goals for those without diabetesmellitus (DM) and 60 years and those <60 years were <150/90 mmHg and <140/90 mmHg, respectively. For those with DM irrespective ofage, the BP goal was <140/90 mmHg.
Mentions: 2 summarizes goal attainment rates (smoking, BMI, HbA1c, LDL-C, and BP) in very high ASCVD risk patients stratified by gender. Males were more likely to attain BMI <25 kg/m2 (18 vs. 9%; P < .001), LDL-C (30 vs. 20%; P < .001) and BP (58 vs. 53%; P < .001) goal achievements when compared with females. Females on the other hand were less likely to smoke (98 vs. 81%; P < .001).

View Article: PubMed Central - PubMed

ABSTRACT

We evaluated the control of cardiovascular disease (CVD) risk factors among patients with atherosclerotic cardiovascular disease (ASCVD) in the Centralized Pan-Middle East Survey on the undertreatment of hypercholesterolaemia (CEPHEUS) in the Arabian Gulf. Of the 4398 enrolled patients, overall mean age was 57 &plusmn; 11 years, 60% were males, 13% were smokers, 76% had diabetes, 71% had metabolic syndrome and 78% had very high ASCVD risk status. The proportion of subjects with body mass index &lt;25 kg/m2, HbA1c &lt;7% (in diabetics), low-density lipoprotein cholesterol (LDL-C) &lt;2.6 mmol/L (100 mg/dL) and &lt;1.8 mmol/L (70 mg/dL) for high and very high ASCVD risk cohorts, respectively and controlled blood pressure (&lt;140/90 mmHg) was 14, 26, 31% and 60%, respectively. Only 1.4% of the participants had all of their CVD risk factors controlled with significant differences among the countries (P &lt; .001). CVD risk goal attainment rates were significantly lower in those with very high ASCVD risk compared with those with high ASCVD risk status (P &lt; .001). Females were also, generally, less likely to attain goals when compared with males (P &lt; .001).

No MeSH data available.


Related in: MedlinePlus