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Distribution of serological screening markers at a large hematology and hemotherapy center in Minas Gerais, Southeastern Brazil

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ABSTRACT

Objective: To assess the distribution of serological markers in blood donors at the blood banks of the Fundação Centro de Hematologia e Hemoterapia de Minas Gerais (Hemominas), Brazil, between January 2006 and December 2012.

Methods: This is a descriptive, retrospective study on blood donors screened using serological tests for markers of transmitted diseases at the state blood-banking network.

Results: Approximately 78.9% of the donors were considered eligible for the study after clinical screening. Repeat donors represented 68.2% of the total sample, with males being predominant as blood donors (66.8%). Total serological ineligibility was 3.05%, with total anti-HBc being the most common marker (1.26%), followed by syphilis (0.88%) and human immunodeficiency virus (0.36%). The prevalences of the markers for hepatitis C, Human T-cell lymphotropic virus, Chagas disease and HBs-Ag were 0.15%, 0.09%, 0.13% and 0.18%, respectively. The blood bank of Governador Valadares had the highest percentage of positive anti-HBc donors (2.41%). With regard to human immunodeficiency virus, the blood bank of Além Paraíba had the lowest percentage of positive donors while the blood banks of Juiz de Fora and Betim had the highest percentages. The blood bank in the city of Montes Claros had the highest prevalence of the marker for Chagas disease (0.69%).

Conclusions: Data on the profile of serological ineligibility by the blood banks of the Fundação Hemominas highlights the particularities of each region thereby contributing to measures for health surveillance and helping the blood donation network in its donor selection procedures aimed at improving blood transfusion safety.

No MeSH data available.


Distribution of serological markers per blood bank of the Fundação Hemominas between 2006 and 2012.
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fig0005: Distribution of serological markers per blood bank of the Fundação Hemominas between 2006 and 2012.

Mentions: Considering the clinically eligible donors, Figure 1 shows the percentages of donations from donors with positive serology for syphilis, anti-HBc, Chagas disease, HTLV, HBsAG, HCV, and HIV at each blood bank. The blood bank in Governador Valadares had the highest percentage of positive anti-HBc donors (Figure 1b). Positivity for the serological marker for Chagas disease was more common in the Montes Claros and Diamantina blood banks; the cities are situated in the northern region of the state and the Jequitinhonha Valley, respectively, where the disease is endemic.13, 14 Serological markers for HBs-Ag and HCV were more commonly observed in the Poços de Caldas blood bank (Figure 1e and f).


Distribution of serological screening markers at a large hematology and hemotherapy center in Minas Gerais, Southeastern Brazil
Distribution of serological markers per blood bank of the Fundação Hemominas between 2006 and 2012.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4997899&req=5

fig0005: Distribution of serological markers per blood bank of the Fundação Hemominas between 2006 and 2012.
Mentions: Considering the clinically eligible donors, Figure 1 shows the percentages of donations from donors with positive serology for syphilis, anti-HBc, Chagas disease, HTLV, HBsAG, HCV, and HIV at each blood bank. The blood bank in Governador Valadares had the highest percentage of positive anti-HBc donors (Figure 1b). Positivity for the serological marker for Chagas disease was more common in the Montes Claros and Diamantina blood banks; the cities are situated in the northern region of the state and the Jequitinhonha Valley, respectively, where the disease is endemic.13, 14 Serological markers for HBs-Ag and HCV were more commonly observed in the Poços de Caldas blood bank (Figure 1e and f).

View Article: PubMed Central - PubMed

ABSTRACT

Objective: To assess the distribution of serological markers in blood donors at the blood banks of the Fundação Centro de Hematologia e Hemoterapia de Minas Gerais (Hemominas), Brazil, between January 2006 and December 2012.

Methods: This is a descriptive, retrospective study on blood donors screened using serological tests for markers of transmitted diseases at the state blood-banking network.

Results: Approximately 78.9% of the donors were considered eligible for the study after clinical screening. Repeat donors represented 68.2% of the total sample, with males being predominant as blood donors (66.8%). Total serological ineligibility was 3.05%, with total anti-HBc being the most common marker (1.26%), followed by syphilis (0.88%) and human immunodeficiency virus (0.36%). The prevalences of the markers for hepatitis C, Human T-cell lymphotropic virus, Chagas disease and HBs-Ag were 0.15%, 0.09%, 0.13% and 0.18%, respectively. The blood bank of Governador Valadares had the highest percentage of positive anti-HBc donors (2.41%). With regard to human immunodeficiency virus, the blood bank of Além Paraíba had the lowest percentage of positive donors while the blood banks of Juiz de Fora and Betim had the highest percentages. The blood bank in the city of Montes Claros had the highest prevalence of the marker for Chagas disease (0.69%).

Conclusions: Data on the profile of serological ineligibility by the blood banks of the Fundação Hemominas highlights the particularities of each region thereby contributing to measures for health surveillance and helping the blood donation network in its donor selection procedures aimed at improving blood transfusion safety.

No MeSH data available.