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Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013.

Kyu HH, Bachman VF, Alexander LT, Mumford JE, Afshin A, Estep K, Veerman JL, Delwiche K, Iannarone ML, Moyer ML, Cercy K, Vos T, Murray CJ, Forouzanfar MH - BMJ (2016)

Bottom Line: An increase from 600 to 3600 MET minutes/week reduced the risk by an additional 19%.Compared with insufficiently active individuals (total activity <600 MET minutes/week), the risk reduction for those in the highly active category (≥8000 MET minutes/week) was 14% (relative risk 0.863, 95% uncertainty interval 0.829 to 0.900) for breast cancer; 21% (0.789, 0.735 to 0.850) for colon cancer; 28% (0.722, 0.678 to 0.768) for diabetes; 25% (0.754, 0.704 to 0.809) for ischemic heart disease; and 26% (0.736, 0.659 to 0.811) for ischemic stroke.  People who achieve total physical activity levels several times higher than the current recommended minimum level have a significant reduction in the risk of the five diseases studied.More studies with detailed quantification of total physical activity will help to find more precise relative risk estimates for different levels of activity.

View Article: PubMed Central - PubMed

Affiliation: Institute for Health Metrics and Evaluation, University of Washington, 2301 5th Avenue, Suite 600, Seattle, WA 98121, USA.

No MeSH data available.


Related in: MedlinePlus

Fig 2 Continuous risk curve for association between physical activity and breast cancer. For each datapoint in included studies, which are represented by different colors, length of horizontal bar refers to total physical activity interval in MET-minutes/week and vertical bar refers to confidence interval of relative risks
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f2: Fig 2 Continuous risk curve for association between physical activity and breast cancer. For each datapoint in included studies, which are represented by different colors, length of horizontal bar refers to total physical activity interval in MET-minutes/week and vertical bar refers to confidence interval of relative risks


Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013.

Kyu HH, Bachman VF, Alexander LT, Mumford JE, Afshin A, Estep K, Veerman JL, Delwiche K, Iannarone ML, Moyer ML, Cercy K, Vos T, Murray CJ, Forouzanfar MH - BMJ (2016)

Fig 2 Continuous risk curve for association between physical activity and breast cancer. For each datapoint in included studies, which are represented by different colors, length of horizontal bar refers to total physical activity interval in MET-minutes/week and vertical bar refers to confidence interval of relative risks
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4979358&req=5

f2: Fig 2 Continuous risk curve for association between physical activity and breast cancer. For each datapoint in included studies, which are represented by different colors, length of horizontal bar refers to total physical activity interval in MET-minutes/week and vertical bar refers to confidence interval of relative risks
Bottom Line: An increase from 600 to 3600 MET minutes/week reduced the risk by an additional 19%.Compared with insufficiently active individuals (total activity <600 MET minutes/week), the risk reduction for those in the highly active category (≥8000 MET minutes/week) was 14% (relative risk 0.863, 95% uncertainty interval 0.829 to 0.900) for breast cancer; 21% (0.789, 0.735 to 0.850) for colon cancer; 28% (0.722, 0.678 to 0.768) for diabetes; 25% (0.754, 0.704 to 0.809) for ischemic heart disease; and 26% (0.736, 0.659 to 0.811) for ischemic stroke.  People who achieve total physical activity levels several times higher than the current recommended minimum level have a significant reduction in the risk of the five diseases studied.More studies with detailed quantification of total physical activity will help to find more precise relative risk estimates for different levels of activity.

View Article: PubMed Central - PubMed

Affiliation: Institute for Health Metrics and Evaluation, University of Washington, 2301 5th Avenue, Suite 600, Seattle, WA 98121, USA.

No MeSH data available.


Related in: MedlinePlus