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Congenital Zika syndrome with arthrogryposis: retrospective case series study.

van der Linden V, Filho EL, Lins OG, van der Linden A, Aragão Mde F, Brainer-Lima AM, Cruz DD, Rocha MA, Sobral da Silva PF, Carvalho MD, do Amaral FJ, Gomes JA, Ribeiro de Medeiros IC, Ventura CV, Ramos RC - BMJ (2016)

Bottom Line: Moderate signs of remodeling of the motor units and a reduced recruitment pattern were found on needle electromyography (monopolar).All presented malformations of cortical development, calcifications predominantly in the cortex and subcortical white matter (especially in the junction between the cortex and white matter), reduction in brain volume, ventriculomegaly, and hypoplasia of the brainstem and cerebellum.MRI of the spine in four children showed apparent thinning of the cord and reduced ventral roots.

View Article: PubMed Central - PubMed

Affiliation: Association for Assistance of Disabled Children, AACD, Recife, Brazil Barão de Lucena Hospital, HBL, Recife, Brazil vanessavdlinden@hotmail.com.

No MeSH data available.


Related in: MedlinePlus

Fig 2 (A) Magnetic resonance image showing bilateral dislocation of hips, epiphyseal core (small arrow), and dysplastic acetabulum (large arrow); (B) 3D computed tomogram showing bilateral dislocation of hips; (C) anteroposterior radiographs showing features compatible with dislocation of hips: interruption of Shenton’s arc , epiphysis hypoplastic proximal femoral acetabular index of 35 degrees, and right and left proximal femoral epiphysis located laterally on side and bottom quadrant ombredanne; (D) radiograph shows subluxation of knee (arrows)
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f2: Fig 2 (A) Magnetic resonance image showing bilateral dislocation of hips, epiphyseal core (small arrow), and dysplastic acetabulum (large arrow); (B) 3D computed tomogram showing bilateral dislocation of hips; (C) anteroposterior radiographs showing features compatible with dislocation of hips: interruption of Shenton’s arc , epiphysis hypoplastic proximal femoral acetabular index of 35 degrees, and right and left proximal femoral epiphysis located laterally on side and bottom quadrant ombredanne; (D) radiograph shows subluxation of knee (arrows)

Mentions: Hip radiographs showed bilateral dislocation in seven children, subluxation of the knee associated with genu valgus in three children (43%), bilateral in two (29%). In all the children, no dysplastic changes were identified on simple radiographs of the appendicular skeleton and spine and none were identified in either the sagittal or coronal plane; dysplastic changes were identified in the dislocated hips, related to dysplastic acetabular (acetabular index >30 degrees). Table 2 shows the main deformities most often found in the children, and figure 2 shows some radiological features.


Congenital Zika syndrome with arthrogryposis: retrospective case series study.

van der Linden V, Filho EL, Lins OG, van der Linden A, Aragão Mde F, Brainer-Lima AM, Cruz DD, Rocha MA, Sobral da Silva PF, Carvalho MD, do Amaral FJ, Gomes JA, Ribeiro de Medeiros IC, Ventura CV, Ramos RC - BMJ (2016)

Fig 2 (A) Magnetic resonance image showing bilateral dislocation of hips, epiphyseal core (small arrow), and dysplastic acetabulum (large arrow); (B) 3D computed tomogram showing bilateral dislocation of hips; (C) anteroposterior radiographs showing features compatible with dislocation of hips: interruption of Shenton’s arc , epiphysis hypoplastic proximal femoral acetabular index of 35 degrees, and right and left proximal femoral epiphysis located laterally on side and bottom quadrant ombredanne; (D) radiograph shows subluxation of knee (arrows)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4979356&req=5

f2: Fig 2 (A) Magnetic resonance image showing bilateral dislocation of hips, epiphyseal core (small arrow), and dysplastic acetabulum (large arrow); (B) 3D computed tomogram showing bilateral dislocation of hips; (C) anteroposterior radiographs showing features compatible with dislocation of hips: interruption of Shenton’s arc , epiphysis hypoplastic proximal femoral acetabular index of 35 degrees, and right and left proximal femoral epiphysis located laterally on side and bottom quadrant ombredanne; (D) radiograph shows subluxation of knee (arrows)
Mentions: Hip radiographs showed bilateral dislocation in seven children, subluxation of the knee associated with genu valgus in three children (43%), bilateral in two (29%). In all the children, no dysplastic changes were identified on simple radiographs of the appendicular skeleton and spine and none were identified in either the sagittal or coronal plane; dysplastic changes were identified in the dislocated hips, related to dysplastic acetabular (acetabular index >30 degrees). Table 2 shows the main deformities most often found in the children, and figure 2 shows some radiological features.

Bottom Line: Moderate signs of remodeling of the motor units and a reduced recruitment pattern were found on needle electromyography (monopolar).All presented malformations of cortical development, calcifications predominantly in the cortex and subcortical white matter (especially in the junction between the cortex and white matter), reduction in brain volume, ventriculomegaly, and hypoplasia of the brainstem and cerebellum.MRI of the spine in four children showed apparent thinning of the cord and reduced ventral roots.

View Article: PubMed Central - PubMed

Affiliation: Association for Assistance of Disabled Children, AACD, Recife, Brazil Barão de Lucena Hospital, HBL, Recife, Brazil vanessavdlinden@hotmail.com.

No MeSH data available.


Related in: MedlinePlus