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A Unique Case of an Aggressive Gangliocytic Paraganglioma of the Filum Terminale.

Akbik OS, Floruta C, Chohan MO, SantaCruz KS, Carlson AP - Case Rep Surg (2016)

Bottom Line: Paragangliomas are rare neuroendocrine tumors that are mostly found in the head and neck.The growth pattern is documented over three years, which to our knowledge has not previously been reported in the literature and is different from the natural history.Clinical, radiological, and pathological characteristics of the tumor are discussed in light of available reports of this rare tumor.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, University of New Mexico, Albuquerque, NM 87131, USA.

ABSTRACT
Paragangliomas are rare neuroendocrine tumors that are mostly found in the head and neck. Even less common are gangliocytic variant paragangliomas of the spine for which there are only 7 other documented cases in the literature. We report a case of gangliocytic paraganglioma of the sacral spine in a 68-year-old man. The growth pattern is documented over three years, which to our knowledge has not previously been reported in the literature and is different from the natural history. Clinical, radiological, and pathological characteristics of the tumor are discussed in light of available reports of this rare tumor.

No MeSH data available.


Related in: MedlinePlus

MRI of the lumbar spine with and without contrast. (a) Sagittal T2, (b) sagittal T1, and (c) sagittal T1 after fat saturation: significant enlargement of previously noted sacral mass with new bony erosion and significant mass effect within the spinal canal causing displacement of posterior spinal structures. The mass has taken a more lobulated appearance as seen on the T2 images and is vividly contrast enhancing.
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fig3: MRI of the lumbar spine with and without contrast. (a) Sagittal T2, (b) sagittal T1, and (c) sagittal T1 after fat saturation: significant enlargement of previously noted sacral mass with new bony erosion and significant mass effect within the spinal canal causing displacement of posterior spinal structures. The mass has taken a more lobulated appearance as seen on the T2 images and is vividly contrast enhancing.

Mentions: A 68-year-old male with a history of multiple lumbar spine decompressive surgeries for lumbar stenosis and radiculopathy was found to have an incidental sacral mass measuring 3.4 × 1.2 cm located intradurally at the S1, S2 level (Figure 1). An MRI brain showed superficial siderosis primarily in the posterior fossa likely due to hemorrhage from the sacral mass which then deposited in the posterior fossa (Figure 2). A repeat MRI in 6 months was ordered; however, the patient was lost to follow-up until he represented 3 years later to the ED with complaints of perianal paresthesia and significant postvoid residuals. Repeat MRI showed significant enlargement of the sacral mass, which now measured 6.0 × 6.2 cm with an increasingly heterogeneous and lobular pattern. The vividly contrast enhanced lesion now was causing significant compression on the sacral nerve roots (Figure 3).


A Unique Case of an Aggressive Gangliocytic Paraganglioma of the Filum Terminale.

Akbik OS, Floruta C, Chohan MO, SantaCruz KS, Carlson AP - Case Rep Surg (2016)

MRI of the lumbar spine with and without contrast. (a) Sagittal T2, (b) sagittal T1, and (c) sagittal T1 after fat saturation: significant enlargement of previously noted sacral mass with new bony erosion and significant mass effect within the spinal canal causing displacement of posterior spinal structures. The mass has taken a more lobulated appearance as seen on the T2 images and is vividly contrast enhancing.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4940518&req=5

fig3: MRI of the lumbar spine with and without contrast. (a) Sagittal T2, (b) sagittal T1, and (c) sagittal T1 after fat saturation: significant enlargement of previously noted sacral mass with new bony erosion and significant mass effect within the spinal canal causing displacement of posterior spinal structures. The mass has taken a more lobulated appearance as seen on the T2 images and is vividly contrast enhancing.
Mentions: A 68-year-old male with a history of multiple lumbar spine decompressive surgeries for lumbar stenosis and radiculopathy was found to have an incidental sacral mass measuring 3.4 × 1.2 cm located intradurally at the S1, S2 level (Figure 1). An MRI brain showed superficial siderosis primarily in the posterior fossa likely due to hemorrhage from the sacral mass which then deposited in the posterior fossa (Figure 2). A repeat MRI in 6 months was ordered; however, the patient was lost to follow-up until he represented 3 years later to the ED with complaints of perianal paresthesia and significant postvoid residuals. Repeat MRI showed significant enlargement of the sacral mass, which now measured 6.0 × 6.2 cm with an increasingly heterogeneous and lobular pattern. The vividly contrast enhanced lesion now was causing significant compression on the sacral nerve roots (Figure 3).

Bottom Line: Paragangliomas are rare neuroendocrine tumors that are mostly found in the head and neck.The growth pattern is documented over three years, which to our knowledge has not previously been reported in the literature and is different from the natural history.Clinical, radiological, and pathological characteristics of the tumor are discussed in light of available reports of this rare tumor.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, University of New Mexico, Albuquerque, NM 87131, USA.

ABSTRACT
Paragangliomas are rare neuroendocrine tumors that are mostly found in the head and neck. Even less common are gangliocytic variant paragangliomas of the spine for which there are only 7 other documented cases in the literature. We report a case of gangliocytic paraganglioma of the sacral spine in a 68-year-old man. The growth pattern is documented over three years, which to our knowledge has not previously been reported in the literature and is different from the natural history. Clinical, radiological, and pathological characteristics of the tumor are discussed in light of available reports of this rare tumor.

No MeSH data available.


Related in: MedlinePlus