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Disorganization, COMT, and Children's Social Behavior: The Norwegian Hypothesis of Legacy of Disorganized Attachment.

Li Z, Hygen BW, Widaman KF, Berg-Nielsen TS, Wichstrøm L, Belsky J - Front Psychol (2016)

Bottom Line: Hygen et al. (2014) proposed that variation in the Catechol-O-methyl transferase(COMT) Val158Met genotype explains this variation, providing preliminary data to this effect.We offer a conceptual replication, analyzing data on 560 children (males: 275) drawn from the NICHD Study of Early Child Care and Youth Development.As predicted, competitive model-fitting indicated that disorganized infants carrying Met alleles engage in more positive behavior and less negative behavior than other children at age 5 and 11, with the reverse true of Val/Val homozygotes, seemingly consistent with caregiving-controlling and punitive-controlling styles, respectively, but only in the case of maternal and not teacher reports, thereby confirmating a relationship-specific hypothesis.

View Article: PubMed Central - PubMed

Affiliation: Department of Human Ecology, University of California, Davis Davis, CA, USA.

ABSTRACT
Why is disorganized attachment associated with punitive-controlling behavior in some, but caregiving-controlling in others? Hygen et al. (2014) proposed that variation in the Catechol-O-methyl transferase(COMT) Val158Met genotype explains this variation, providing preliminary data to this effect. We offer a conceptual replication, analyzing data on 560 children (males: 275) drawn from the NICHD Study of Early Child Care and Youth Development. As predicted, competitive model-fitting indicated that disorganized infants carrying Met alleles engage in more positive behavior and less negative behavior than other children at age 5 and 11, with the reverse true of Val/Val homozygotes, seemingly consistent with caregiving-controlling and punitive-controlling styles, respectively, but only in the case of maternal and not teacher reports, thereby confirmating a relationship-specific hypothesis.

No MeSH data available.


Hypothesized COMT X disorganization interaction pattern for mother-reported positive and negative child behavior (“0” = organized; “1” = disorganized).
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Figure 1: Hypothesized COMT X disorganization interaction pattern for mother-reported positive and negative child behavior (“0” = organized; “1” = disorganized).

Mentions: Based on the original Norwegian hypothesis, this conceptual replication specifically, directly and collectively tests the following multiple propositions graphically depicted in Figure 1: (a) kindergarteners with a history of disorganized attachment who are homozygous for the Val allele will score higher on aggression and lower on social competence, reflecting a punitive-controlling behavioral style, than will non-disorganized/organized children; (b) kindergarteners with a history of disorganized attachment carrying the Met allele, will score lower on aggression and higher on social competence, reflecting a caregiving-controlling behavioral style than will non-disorganized/organized children; and (c) because disorganization, by definition, refers to the nature of a relationship that a child has with his or her caregiver, and that children's punitive and caregiving behavior are only activated by, and within the (parent-child) attachment system, these differential developmental legacies of disorganized attachment will be evident only in maternal, not teacher reports; finally (d) children who do not have a history of disorganized attachment will not exhibit differential aggression or social competence outcomes as a function of their COMT gene allelic status.


Disorganization, COMT, and Children's Social Behavior: The Norwegian Hypothesis of Legacy of Disorganized Attachment.

Li Z, Hygen BW, Widaman KF, Berg-Nielsen TS, Wichstrøm L, Belsky J - Front Psychol (2016)

Hypothesized COMT X disorganization interaction pattern for mother-reported positive and negative child behavior (“0” = organized; “1” = disorganized).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4940399&req=5

Figure 1: Hypothesized COMT X disorganization interaction pattern for mother-reported positive and negative child behavior (“0” = organized; “1” = disorganized).
Mentions: Based on the original Norwegian hypothesis, this conceptual replication specifically, directly and collectively tests the following multiple propositions graphically depicted in Figure 1: (a) kindergarteners with a history of disorganized attachment who are homozygous for the Val allele will score higher on aggression and lower on social competence, reflecting a punitive-controlling behavioral style, than will non-disorganized/organized children; (b) kindergarteners with a history of disorganized attachment carrying the Met allele, will score lower on aggression and higher on social competence, reflecting a caregiving-controlling behavioral style than will non-disorganized/organized children; and (c) because disorganization, by definition, refers to the nature of a relationship that a child has with his or her caregiver, and that children's punitive and caregiving behavior are only activated by, and within the (parent-child) attachment system, these differential developmental legacies of disorganized attachment will be evident only in maternal, not teacher reports; finally (d) children who do not have a history of disorganized attachment will not exhibit differential aggression or social competence outcomes as a function of their COMT gene allelic status.

Bottom Line: Hygen et al. (2014) proposed that variation in the Catechol-O-methyl transferase(COMT) Val158Met genotype explains this variation, providing preliminary data to this effect.We offer a conceptual replication, analyzing data on 560 children (males: 275) drawn from the NICHD Study of Early Child Care and Youth Development.As predicted, competitive model-fitting indicated that disorganized infants carrying Met alleles engage in more positive behavior and less negative behavior than other children at age 5 and 11, with the reverse true of Val/Val homozygotes, seemingly consistent with caregiving-controlling and punitive-controlling styles, respectively, but only in the case of maternal and not teacher reports, thereby confirmating a relationship-specific hypothesis.

View Article: PubMed Central - PubMed

Affiliation: Department of Human Ecology, University of California, Davis Davis, CA, USA.

ABSTRACT
Why is disorganized attachment associated with punitive-controlling behavior in some, but caregiving-controlling in others? Hygen et al. (2014) proposed that variation in the Catechol-O-methyl transferase(COMT) Val158Met genotype explains this variation, providing preliminary data to this effect. We offer a conceptual replication, analyzing data on 560 children (males: 275) drawn from the NICHD Study of Early Child Care and Youth Development. As predicted, competitive model-fitting indicated that disorganized infants carrying Met alleles engage in more positive behavior and less negative behavior than other children at age 5 and 11, with the reverse true of Val/Val homozygotes, seemingly consistent with caregiving-controlling and punitive-controlling styles, respectively, but only in the case of maternal and not teacher reports, thereby confirmating a relationship-specific hypothesis.

No MeSH data available.