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Does radiofrequency ablation (RFA) epiphysiodesis affect adjacent joint cartilage?

Shiguetomi-Medina JM, Rahbek O, Abood AA, Stødkilde-Jørgensen H, Ramírez Garcia-Luna JL, Møller-Madsen B - J Child Orthop (2016)

Bottom Line: We found no evidence of articular cartilage damage on the 40 8-min RFA procedures.The tibiae ablated for 16 min and 24 min showed intact joint cartilage.This study shows that RFA can be done safely in the growing physis of pigs, even with triple duration procedures.

View Article: PubMed Central - PubMed

Affiliation: Orthopaedic Research Laboratory, Danish Paediatric Orthopaedic Research, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark. jmshigue@gmail.com.

ABSTRACT

Purpose: To test the hypothesis that epiphysiodesis made with radiofrequency ablation (RFA) is a safe procedure that disrupts the growth plate without damaging the adjacent joint articular cartilage.

Methods: RFA epiphysiodesis was done during 8 min in vivo in 40 growing pig tibia physis. In addition, three tibiae were ablated for 16 min and three more for 24 min. As a burned cartilage reference, six tibiae were ablated on the joint articular cartilage for 8 min. After the procedure, the animals were terminated and the tibiae were harvested. Magnetic resonance imaging (MRI) was done ex vivo to evaluate the joint articular cartilage in all samples. We used T1-weighted, T2-weighted, and water content sequences under a 1.5 T magnetic field.

Results: On the burned articular cartilage, intensity changes were observed at MRI. We found no evidence of articular cartilage damage on the 40 8-min RFA procedures. The tibiae ablated for 16 min and 24 min showed intact joint cartilage.

Conclusions: Epiphysiodesis using RFA is safe for the adjacent articular cartilage. This study shows that RFA can be done safely in the growing physis of pigs, even with triple duration procedures.

No MeSH data available.


Related in: MedlinePlus

Burned cartilage water content calculation. An area of interest was established around the intentionally burned joint cartilage (yellow). Based on the mean T1 value, the water content was calculated
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Fig5: Burned cartilage water content calculation. An area of interest was established around the intentionally burned joint cartilage (yellow). Based on the mean T1 value, the water content was calculated

Mentions: A hyper-intensity was observed at the ablation area (Fig. 4). T1 values from these areas were increased by 30 % on average (20–42 %) (Fig. 5; Table 1).Fig. 4


Does radiofrequency ablation (RFA) epiphysiodesis affect adjacent joint cartilage?

Shiguetomi-Medina JM, Rahbek O, Abood AA, Stødkilde-Jørgensen H, Ramírez Garcia-Luna JL, Møller-Madsen B - J Child Orthop (2016)

Burned cartilage water content calculation. An area of interest was established around the intentionally burned joint cartilage (yellow). Based on the mean T1 value, the water content was calculated
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4940242&req=5

Fig5: Burned cartilage water content calculation. An area of interest was established around the intentionally burned joint cartilage (yellow). Based on the mean T1 value, the water content was calculated
Mentions: A hyper-intensity was observed at the ablation area (Fig. 4). T1 values from these areas were increased by 30 % on average (20–42 %) (Fig. 5; Table 1).Fig. 4

Bottom Line: We found no evidence of articular cartilage damage on the 40 8-min RFA procedures.The tibiae ablated for 16 min and 24 min showed intact joint cartilage.This study shows that RFA can be done safely in the growing physis of pigs, even with triple duration procedures.

View Article: PubMed Central - PubMed

Affiliation: Orthopaedic Research Laboratory, Danish Paediatric Orthopaedic Research, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark. jmshigue@gmail.com.

ABSTRACT

Purpose: To test the hypothesis that epiphysiodesis made with radiofrequency ablation (RFA) is a safe procedure that disrupts the growth plate without damaging the adjacent joint articular cartilage.

Methods: RFA epiphysiodesis was done during 8 min in vivo in 40 growing pig tibia physis. In addition, three tibiae were ablated for 16 min and three more for 24 min. As a burned cartilage reference, six tibiae were ablated on the joint articular cartilage for 8 min. After the procedure, the animals were terminated and the tibiae were harvested. Magnetic resonance imaging (MRI) was done ex vivo to evaluate the joint articular cartilage in all samples. We used T1-weighted, T2-weighted, and water content sequences under a 1.5 T magnetic field.

Results: On the burned articular cartilage, intensity changes were observed at MRI. We found no evidence of articular cartilage damage on the 40 8-min RFA procedures. The tibiae ablated for 16 min and 24 min showed intact joint cartilage.

Conclusions: Epiphysiodesis using RFA is safe for the adjacent articular cartilage. This study shows that RFA can be done safely in the growing physis of pigs, even with triple duration procedures.

No MeSH data available.


Related in: MedlinePlus