Limits...
A little-known relationship between immune recovery syndrome and herpes zoster.

Bhandage S, Kurki M, Hosur V, Sukhija P, Bajoria A - J Korean Assoc Oral Maxillofac Surg (2016)

Bottom Line: This is a result of improved immunity brought about by ART, also termed immune recovery syndrome.The patient had a history of being on ART two months earlier and a history of tooth extraction eight days prior to his arrival at our institute.In addition, the treating physician should maintain a high level of vigilance for the patient during the first few months of ART, the peak incidence of immune recovery inflammatory disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Sri Hasanamba Dental College and Hospital, Hassan, India.

ABSTRACT
Following anti-retroviral therapy (ART) or highly active antiretroviral therapy, there is an increased response to latent infections such as herpes zoster, which may lead to their reactivation. This is a result of improved immunity brought about by ART, also termed immune recovery syndrome. A 75-year-old male patient arrived at our institute with widespread vesicles and scabs on the right half of his face and oral cavity, suggesting the involvement of the trigeminal nerve. The patient had a history of being on ART two months earlier and a history of tooth extraction eight days prior to his arrival at our institute. The incidence of human immunodeficiency virus (HIV)-positive cases amongst herpes zoster cases is high, and these patients become susceptible to infections following ART. Therefore, regardless of the presence of risk factors, every herpes zoster patient should be tested for HIV infection, and high anti-retroviral therapy should be commenced/reinstituted as soon as possible. In addition, the treating physician should maintain a high level of vigilance for the patient during the first few months of ART, the peak incidence of immune recovery inflammatory disease.

No MeSH data available.


Related in: MedlinePlus

Multiple scabs and vesicles.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4940204&req=5

Figure 2: Multiple scabs and vesicles.

Mentions: The patient was conscious, delirious, irritable, and appeared tired and distressed. He was moderately built and poorly nourished. There was history of a loss of appetite and weakness for the past six months. On examination, multiple cutaneous vesicles and scabs covered the same side of his cheek, ear, upper and lower lips, chin, and submandibular region.(Fig. 1) Mild diffuse swelling on the right half of the lips was noted, and generalized ulceration of the right buccal and labial mucosa was present.(Fig. 2, 3) Ulcerations on the anterior two-thirds of the right half of the tongue, lingual mucosa, tonsillar pillars, and the soft palate were also present. The ulcers were irregular and more than a centimeter in size and were covered with slough. The patient also complained of restriction in his jaw opening due to severe pain. There were no signs of systemic dissemination.


A little-known relationship between immune recovery syndrome and herpes zoster.

Bhandage S, Kurki M, Hosur V, Sukhija P, Bajoria A - J Korean Assoc Oral Maxillofac Surg (2016)

Multiple scabs and vesicles.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4940204&req=5

Figure 2: Multiple scabs and vesicles.
Mentions: The patient was conscious, delirious, irritable, and appeared tired and distressed. He was moderately built and poorly nourished. There was history of a loss of appetite and weakness for the past six months. On examination, multiple cutaneous vesicles and scabs covered the same side of his cheek, ear, upper and lower lips, chin, and submandibular region.(Fig. 1) Mild diffuse swelling on the right half of the lips was noted, and generalized ulceration of the right buccal and labial mucosa was present.(Fig. 2, 3) Ulcerations on the anterior two-thirds of the right half of the tongue, lingual mucosa, tonsillar pillars, and the soft palate were also present. The ulcers were irregular and more than a centimeter in size and were covered with slough. The patient also complained of restriction in his jaw opening due to severe pain. There were no signs of systemic dissemination.

Bottom Line: This is a result of improved immunity brought about by ART, also termed immune recovery syndrome.The patient had a history of being on ART two months earlier and a history of tooth extraction eight days prior to his arrival at our institute.In addition, the treating physician should maintain a high level of vigilance for the patient during the first few months of ART, the peak incidence of immune recovery inflammatory disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Sri Hasanamba Dental College and Hospital, Hassan, India.

ABSTRACT
Following anti-retroviral therapy (ART) or highly active antiretroviral therapy, there is an increased response to latent infections such as herpes zoster, which may lead to their reactivation. This is a result of improved immunity brought about by ART, also termed immune recovery syndrome. A 75-year-old male patient arrived at our institute with widespread vesicles and scabs on the right half of his face and oral cavity, suggesting the involvement of the trigeminal nerve. The patient had a history of being on ART two months earlier and a history of tooth extraction eight days prior to his arrival at our institute. The incidence of human immunodeficiency virus (HIV)-positive cases amongst herpes zoster cases is high, and these patients become susceptible to infections following ART. Therefore, regardless of the presence of risk factors, every herpes zoster patient should be tested for HIV infection, and high anti-retroviral therapy should be commenced/reinstituted as soon as possible. In addition, the treating physician should maintain a high level of vigilance for the patient during the first few months of ART, the peak incidence of immune recovery inflammatory disease.

No MeSH data available.


Related in: MedlinePlus