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Influence of Smoking Consumption and Nicotine Dependence Degree inCardiac Autonomic Modulation

View Article: PubMed Central - PubMed

ABSTRACT

Background: Smoking consumption alters cardiac autonomic function.

Objective: Assess the influence of the intensity of smoking and the nicotine dependencedegree in cardiac autonomic modulation evaluated through index of heart ratevariability (HRV).

Methods: 83 smokers, of both genders, between 50 and 70 years of age and with normallung function were divided according to the intensity of smoking consumption(moderate and severe) and the nicotine dependency degree (mild, moderate andsevere). The indexes of HRV were analyzed in rest condition, in linearmethods in the time domain (TD), the frequency domain (FD) and through thePoincaré plot. For the comparison of smoking consumption, unpaired ttest or Mann-Whitney was employed. For the analysis between the nicotinedependency degrees, we used the One-way ANOVA test, followed by Tukey's posttest or Kruskal-Wallis followed by Dunn's test. The significance level was p< 0,05.

Results: Differences were only found when compared to the different intensities ofsmoking consumption in the indexes in the FD. LFun (62.89 ± 15.24 vs75.45 ± 10.28), which corresponds to low frequency spectrum componentin normalized units; HFun (37.11 ± 15.24 vs 24.55 ± 10.28),which corresponds to high frequency spectrum component in normalized unitsand in the LF/HF ratio (2.21 ± 1.47 vs 4.07 ± 2.94). However,in the evaluation of nicotine dependency, significant differences were notobserved (p > 0.05).

Conclusion: Only the intensity of smoking consumption had an influence over the cardiacautonomic modulation of the assessed tobacco smokers. Tobacco smokers withsevere intensity of smoking consumption presented a lower autonomicmodulation than those with moderate intensity.

No MeSH data available.


Flowchart of study losses.
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f1: Flowchart of study losses.

Mentions: This study did not include individuals who used narcotics or medications thatinfluenced cardiac autonomic activity, alcoholics, or individuals with knowndiseases such as infections, metabolic or cardiorespiratory diseases. Theflowchart of study losses is presented in Figure1.


Influence of Smoking Consumption and Nicotine Dependence Degree inCardiac Autonomic Modulation
Flowchart of study losses.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4940150&req=5

f1: Flowchart of study losses.
Mentions: This study did not include individuals who used narcotics or medications thatinfluenced cardiac autonomic activity, alcoholics, or individuals with knowndiseases such as infections, metabolic or cardiorespiratory diseases. Theflowchart of study losses is presented in Figure1.

View Article: PubMed Central - PubMed

ABSTRACT

Background: Smoking consumption alters cardiac autonomic function.

Objective: Assess the influence of the intensity of smoking and the nicotine dependencedegree in cardiac autonomic modulation evaluated through index of heart ratevariability (HRV).

Methods: 83 smokers, of both genders, between 50 and 70 years of age and with normallung function were divided according to the intensity of smoking consumption(moderate and severe) and the nicotine dependency degree (mild, moderate andsevere). The indexes of HRV were analyzed in rest condition, in linearmethods in the time domain (TD), the frequency domain (FD) and through thePoincaré plot. For the comparison of smoking consumption, unpaired ttest or Mann-Whitney was employed. For the analysis between the nicotinedependency degrees, we used the One-way ANOVA test, followed by Tukey's posttest or Kruskal-Wallis followed by Dunn's test. The significance level was p< 0,05.

Results: Differences were only found when compared to the different intensities ofsmoking consumption in the indexes in the FD. LFun (62.89 ± 15.24 vs75.45 ± 10.28), which corresponds to low frequency spectrum componentin normalized units; HFun (37.11 ± 15.24 vs 24.55 ± 10.28),which corresponds to high frequency spectrum component in normalized unitsand in the LF/HF ratio (2.21 ± 1.47 vs 4.07 ± 2.94). However,in the evaluation of nicotine dependency, significant differences were notobserved (p > 0.05).

Conclusion: Only the intensity of smoking consumption had an influence over the cardiacautonomic modulation of the assessed tobacco smokers. Tobacco smokers withsevere intensity of smoking consumption presented a lower autonomicmodulation than those with moderate intensity.

No MeSH data available.