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Age-dependent vitreous separation from the macula in a clinic population.

Syed Z, Stewart MW - Clin Ophthalmol (2016)

Bottom Line: Demographic data and spectral domain optical coherence tomography scan results were gathered.This prevalence rate steadily decreased to 5.6% in the 95- to 99-year age group.The length of vitreomacular adhesion averaged 4.6 mm in the 50- to 54-year age group and steadily decreased to 2.1 mm in the 90- to 95-year group.

View Article: PubMed Central - PubMed

Affiliation: Georgetown University, Washington, DC.

ABSTRACT

Background: Vitreous degeneration begins soon after birth and accelerates throughout life. Vitreous liquefaction with a slowly progressive separation of the posterior hyaloid from the peripheral macula usually leads to complete posterior vitreous detachment. The purpose of this study is to measure the age-related prevalence of partial vitreous separation and the length of residual vitreous adhesion in an ophthalmology clinic population.

Methods: Patients examined by the senior author (MWS) during a 6-month period were included in a retrospective chart review. Demographic data and spectral domain optical coherence tomography scan results were gathered. Data analysis with descriptive statistics focused on the prevalence and extent of partial vitreous separation.

Results: The mean age of the study patients was 69.9 years, and 62% were phakic. The highest prevalence of partial posterior hyaloid separation from the internal limiting membrane (71.2%) was seen in the 50- to 54-year age group. This prevalence rate steadily decreased to 5.6% in the 95- to 99-year age group. The prevalence of complete vitreous detachment as determined by slit-lamp biomicroscopy increased from 1.7% in the <50-year age group to a maximum of 29.2% in the 75- to 79-year group. The length of vitreomacular adhesion averaged 4.6 mm in the 50- to 54-year age group and steadily decreased to 2.1 mm in the 90- to 95-year group.

Conclusion: Vitreomacular separation affects the majority of eyes in the sixth decade of life. The prevalence of partial vitreous separation decreases with advancing age, probably because an increasing number of these patients progress to complete posterior vitreous detachment.

No MeSH data available.


Related in: MedlinePlus

Proportion of normal, macular degeneration, and diabetic retinopathy eyes with partial vitreoretinal separation.Notes: Lengths of vitreomacular adhesion for patients without retinopathy (normal), those with macular degeneration, and those with diabetic retinopathy are plotted. A slight trend toward greater vitreomacular adhesion in elderly patients with diabetic retinopathy is noted.
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f3-opth-10-1237: Proportion of normal, macular degeneration, and diabetic retinopathy eyes with partial vitreoretinal separation.Notes: Lengths of vitreomacular adhesion for patients without retinopathy (normal), those with macular degeneration, and those with diabetic retinopathy are plotted. A slight trend toward greater vitreomacular adhesion in elderly patients with diabetic retinopathy is noted.

Mentions: Patients with normal retinas, macular degeneration, and diabetic retinopathy were evaluated for partial vitreoretinal separation (Figure 3). Patients with macular degeneration resembled those with normal retinas, but there was a nonstatistically significant trend for greater vitreoretinal adhesion in patients with diabetic retinopathy.


Age-dependent vitreous separation from the macula in a clinic population.

Syed Z, Stewart MW - Clin Ophthalmol (2016)

Proportion of normal, macular degeneration, and diabetic retinopathy eyes with partial vitreoretinal separation.Notes: Lengths of vitreomacular adhesion for patients without retinopathy (normal), those with macular degeneration, and those with diabetic retinopathy are plotted. A slight trend toward greater vitreomacular adhesion in elderly patients with diabetic retinopathy is noted.
© Copyright Policy
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4940013&req=5

f3-opth-10-1237: Proportion of normal, macular degeneration, and diabetic retinopathy eyes with partial vitreoretinal separation.Notes: Lengths of vitreomacular adhesion for patients without retinopathy (normal), those with macular degeneration, and those with diabetic retinopathy are plotted. A slight trend toward greater vitreomacular adhesion in elderly patients with diabetic retinopathy is noted.
Mentions: Patients with normal retinas, macular degeneration, and diabetic retinopathy were evaluated for partial vitreoretinal separation (Figure 3). Patients with macular degeneration resembled those with normal retinas, but there was a nonstatistically significant trend for greater vitreoretinal adhesion in patients with diabetic retinopathy.

Bottom Line: Demographic data and spectral domain optical coherence tomography scan results were gathered.This prevalence rate steadily decreased to 5.6% in the 95- to 99-year age group.The length of vitreomacular adhesion averaged 4.6 mm in the 50- to 54-year age group and steadily decreased to 2.1 mm in the 90- to 95-year group.

View Article: PubMed Central - PubMed

Affiliation: Georgetown University, Washington, DC.

ABSTRACT

Background: Vitreous degeneration begins soon after birth and accelerates throughout life. Vitreous liquefaction with a slowly progressive separation of the posterior hyaloid from the peripheral macula usually leads to complete posterior vitreous detachment. The purpose of this study is to measure the age-related prevalence of partial vitreous separation and the length of residual vitreous adhesion in an ophthalmology clinic population.

Methods: Patients examined by the senior author (MWS) during a 6-month period were included in a retrospective chart review. Demographic data and spectral domain optical coherence tomography scan results were gathered. Data analysis with descriptive statistics focused on the prevalence and extent of partial vitreous separation.

Results: The mean age of the study patients was 69.9 years, and 62% were phakic. The highest prevalence of partial posterior hyaloid separation from the internal limiting membrane (71.2%) was seen in the 50- to 54-year age group. This prevalence rate steadily decreased to 5.6% in the 95- to 99-year age group. The prevalence of complete vitreous detachment as determined by slit-lamp biomicroscopy increased from 1.7% in the <50-year age group to a maximum of 29.2% in the 75- to 79-year group. The length of vitreomacular adhesion averaged 4.6 mm in the 50- to 54-year age group and steadily decreased to 2.1 mm in the 90- to 95-year group.

Conclusion: Vitreomacular separation affects the majority of eyes in the sixth decade of life. The prevalence of partial vitreous separation decreases with advancing age, probably because an increasing number of these patients progress to complete posterior vitreous detachment.

No MeSH data available.


Related in: MedlinePlus