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Value of 24-hour Delayed Film of Barium Enema for Evaluation of Colon Transit Function in Young Children with Constipation.

Yoo HY, Son JS, Park HW, Kwak BO, Kim HS, Bae SH - J Neurogastroenterol Motil (2016)

Bottom Line: The Spearman correlation coefficient was 0.438 (P < 0.001) for the overall group.The correlation was strongest in children younger than 4 years (r= 0.537, P = 0.032).Although the correlation between BE and CTTRM was not very strong, the 24‑hour delayed BE film could provide broad information about colon transit function in young children, especially those under 4 years who usually cannot undergo CTTRM.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Background/aims: A colon transit time test using radio-opaque markers (CTTRM) is considered the gold standard for evaluating colon transit function. A 24-hour delayed film of barium enema (BE) has been used as a supplementary method in structural evaluations. The aim of this study was to evaluate the utility of a 24-hour delayed BE film for assessing colon transit function in young children with constipation.

Methods: In total, 93 children with constipation who performed both single-contrast BE and CTTRM were enrolled in this study. Of these, the data from 70 children were analyzed (males 33, females 37; mean age [range], 5.63 ± 2.94 [2-14] years). The basic principle of the study is "velocity = distance/time". Time values were identified in both studies, and the colon length and distance of barium movement were measured on the 24-hour delayed BE film. Thus, colon transit velocity values could be calculated using both methods. The correlation between colon transit velocity using a 24-hour delayed BE film versus CTTRM was analyzed statistically.

Results: Median value (interquartile range) of colon transit velocity using CTTRM was 1.57 (1.07-2.89) cm/hr, and that using BE of that was 1.58 (0.94-2.07) cm/hr. The Spearman correlation coefficient was 0.438 (P < 0.001) for the overall group. The correlation was strongest in children younger than 4 years (r= 0.537, P = 0.032).

Conclusions: Although the correlation between BE and CTTRM was not very strong, the 24‑hour delayed BE film could provide broad information about colon transit function in young children, especially those under 4 years who usually cannot undergo CTTRM.

No MeSH data available.


Related in: MedlinePlus

Abdominal X-ray on fourth day (A) and seventh day (B). This was divided into 3 colonic segments. Bony landmarks (fifth lumbar vertebra, the pelvic outlet) defined projection zones of the right colon, left colon, and rectosigmoid colon. The total number of markers in each zone were counted and multiplied by 1.2 [total colon transit time on fourth day = (R + L + RS) × 1.2 = (20 + 2 + 0) × 1.2 = 22 × 1.2 = 26.4 hours]. R, right colon; L, left colon; RS, rectosigmoid colon.
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f1-jnm-22-483: Abdominal X-ray on fourth day (A) and seventh day (B). This was divided into 3 colonic segments. Bony landmarks (fifth lumbar vertebra, the pelvic outlet) defined projection zones of the right colon, left colon, and rectosigmoid colon. The total number of markers in each zone were counted and multiplied by 1.2 [total colon transit time on fourth day = (R + L + RS) × 1.2 = (20 + 2 + 0) × 1.2 = 22 × 1.2 = 26.4 hours]. R, right colon; L, left colon; RS, rectosigmoid colon.

Mentions: Total CTT was performed according to a method by Metcalf et al.12 A Kolomark (MI Tech, Seoul, Korea) capsule, containing 20 radio-opaque markers per capsule, was taken at the same time each day for 3 consecutive days. A plain abdominal X-ray was taken on days 4 and 7, and the number of remaining markers was counted. The CTT was calculated according to the following formula (Fig. 1):


Value of 24-hour Delayed Film of Barium Enema for Evaluation of Colon Transit Function in Young Children with Constipation.

Yoo HY, Son JS, Park HW, Kwak BO, Kim HS, Bae SH - J Neurogastroenterol Motil (2016)

Abdominal X-ray on fourth day (A) and seventh day (B). This was divided into 3 colonic segments. Bony landmarks (fifth lumbar vertebra, the pelvic outlet) defined projection zones of the right colon, left colon, and rectosigmoid colon. The total number of markers in each zone were counted and multiplied by 1.2 [total colon transit time on fourth day = (R + L + RS) × 1.2 = (20 + 2 + 0) × 1.2 = 22 × 1.2 = 26.4 hours]. R, right colon; L, left colon; RS, rectosigmoid colon.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4930304&req=5

f1-jnm-22-483: Abdominal X-ray on fourth day (A) and seventh day (B). This was divided into 3 colonic segments. Bony landmarks (fifth lumbar vertebra, the pelvic outlet) defined projection zones of the right colon, left colon, and rectosigmoid colon. The total number of markers in each zone were counted and multiplied by 1.2 [total colon transit time on fourth day = (R + L + RS) × 1.2 = (20 + 2 + 0) × 1.2 = 22 × 1.2 = 26.4 hours]. R, right colon; L, left colon; RS, rectosigmoid colon.
Mentions: Total CTT was performed according to a method by Metcalf et al.12 A Kolomark (MI Tech, Seoul, Korea) capsule, containing 20 radio-opaque markers per capsule, was taken at the same time each day for 3 consecutive days. A plain abdominal X-ray was taken on days 4 and 7, and the number of remaining markers was counted. The CTT was calculated according to the following formula (Fig. 1):

Bottom Line: The Spearman correlation coefficient was 0.438 (P < 0.001) for the overall group.The correlation was strongest in children younger than 4 years (r= 0.537, P = 0.032).Although the correlation between BE and CTTRM was not very strong, the 24‑hour delayed BE film could provide broad information about colon transit function in young children, especially those under 4 years who usually cannot undergo CTTRM.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Background/aims: A colon transit time test using radio-opaque markers (CTTRM) is considered the gold standard for evaluating colon transit function. A 24-hour delayed film of barium enema (BE) has been used as a supplementary method in structural evaluations. The aim of this study was to evaluate the utility of a 24-hour delayed BE film for assessing colon transit function in young children with constipation.

Methods: In total, 93 children with constipation who performed both single-contrast BE and CTTRM were enrolled in this study. Of these, the data from 70 children were analyzed (males 33, females 37; mean age [range], 5.63 ± 2.94 [2-14] years). The basic principle of the study is "velocity = distance/time". Time values were identified in both studies, and the colon length and distance of barium movement were measured on the 24-hour delayed BE film. Thus, colon transit velocity values could be calculated using both methods. The correlation between colon transit velocity using a 24-hour delayed BE film versus CTTRM was analyzed statistically.

Results: Median value (interquartile range) of colon transit velocity using CTTRM was 1.57 (1.07-2.89) cm/hr, and that using BE of that was 1.58 (0.94-2.07) cm/hr. The Spearman correlation coefficient was 0.438 (P < 0.001) for the overall group. The correlation was strongest in children younger than 4 years (r= 0.537, P = 0.032).

Conclusions: Although the correlation between BE and CTTRM was not very strong, the 24‑hour delayed BE film could provide broad information about colon transit function in young children, especially those under 4 years who usually cannot undergo CTTRM.

No MeSH data available.


Related in: MedlinePlus