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Use of Transcranial Doppler Ultrasound for Diagnosis of Brain Death in Patients with Severe Cerebral Injury.

Li Y, Liu S, Xun F, Liu Z, Huang X - Med. Sci. Monit. (2016)

Bottom Line: The average blood flow velocity (Vm), pulse index (PI), and diastolic blood flow in reverse (RDF) were recorded and compared.RESULTS The data demonstrated that the average speed of bilateral middle cerebral artery blood flow in the brain death group was significantly reduced (P<0.05).However, the PI of the brain death group increased significantly.

View Article: PubMed Central - PubMed

Affiliation: Department of Transcranial Doppler Ultrasound, The Affiliated Hospital of Jining Medical College, Jining, Shandong, China (mainland).

ABSTRACT
BACKGROUND The aim of this study was to investigate the use of transcranial Doppler (TCD) for diagnosis of brain death in patients with severe cerebral injury. MATERIAL AND METHODS This retrospective study enrolled 42 patients based on inclusion and exclusion criteria. All patients were divided into either the brain death group or the survival group according to prognosis. Blood flow of the brain was examined by TCD and analyzed for spectrum changes. The average blood flow velocity (Vm), pulse index (PI), and diastolic blood flow in reverse (RDF) were recorded and compared. RESULTS The data demonstrated that the average speed of bilateral middle cerebral artery blood flow in the brain death group was significantly reduced (P<0.05). However, the PI of the brain death group increased significantly. Moreover, RDF spectrum and nail-like sharp peak spectrum of the brain death group was higher than in the survival group. CONCLUSIONS Due to its simplicity, high repeatability, and specificity, TCD combined with other methods is highly valuable for diagnosis of brain death in patients with severe brain injury.

No MeSH data available.


Related in: MedlinePlus

(A) Oscillation. (B) Sharp peaks. (C) Normal spectrum.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4920100&req=5

f1-medscimonit-22-1910: (A) Oscillation. (B) Sharp peaks. (C) Normal spectrum.

Mentions: Figures 1 and 2 show the spectra of oscillation and sharp peaks in the brain death group and the survival group compared with the normal control spectrum.


Use of Transcranial Doppler Ultrasound for Diagnosis of Brain Death in Patients with Severe Cerebral Injury.

Li Y, Liu S, Xun F, Liu Z, Huang X - Med. Sci. Monit. (2016)

(A) Oscillation. (B) Sharp peaks. (C) Normal spectrum.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4920100&req=5

f1-medscimonit-22-1910: (A) Oscillation. (B) Sharp peaks. (C) Normal spectrum.
Mentions: Figures 1 and 2 show the spectra of oscillation and sharp peaks in the brain death group and the survival group compared with the normal control spectrum.

Bottom Line: The average blood flow velocity (Vm), pulse index (PI), and diastolic blood flow in reverse (RDF) were recorded and compared.RESULTS The data demonstrated that the average speed of bilateral middle cerebral artery blood flow in the brain death group was significantly reduced (P<0.05).However, the PI of the brain death group increased significantly.

View Article: PubMed Central - PubMed

Affiliation: Department of Transcranial Doppler Ultrasound, The Affiliated Hospital of Jining Medical College, Jining, Shandong, China (mainland).

ABSTRACT
BACKGROUND The aim of this study was to investigate the use of transcranial Doppler (TCD) for diagnosis of brain death in patients with severe cerebral injury. MATERIAL AND METHODS This retrospective study enrolled 42 patients based on inclusion and exclusion criteria. All patients were divided into either the brain death group or the survival group according to prognosis. Blood flow of the brain was examined by TCD and analyzed for spectrum changes. The average blood flow velocity (Vm), pulse index (PI), and diastolic blood flow in reverse (RDF) were recorded and compared. RESULTS The data demonstrated that the average speed of bilateral middle cerebral artery blood flow in the brain death group was significantly reduced (P<0.05). However, the PI of the brain death group increased significantly. Moreover, RDF spectrum and nail-like sharp peak spectrum of the brain death group was higher than in the survival group. CONCLUSIONS Due to its simplicity, high repeatability, and specificity, TCD combined with other methods is highly valuable for diagnosis of brain death in patients with severe brain injury.

No MeSH data available.


Related in: MedlinePlus