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Gastric hyperplastic polyp with focal cancer.

Markowski AR, Guzinska-Ustymowicz K - Gastroenterol Rep (Oxf) (2014)

Bottom Line: The frequency of surveillance endoscopy should depend on the precise histopathological diagnosis and possibility of confirming the completeness of the endoscopic resection.If the completeness of the procedure is confirmed both macro- and microscopically, gastric resection does not have to be performed.A follow-up esophago-gastroduodenoscopy should be performed at 1 year and then at 3 years.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, Bialystok, Poland Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, Bialystok, Poland markowski@szpitalpck.pl.

No MeSH data available.


Related in: MedlinePlus

Histopathological findings (hematoxylin-erosin staining, x20/x40). Small focus of adenocarcinoma in the gastric hyperplastic polyp, with a distinct mitotic figure (arrow).
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gou077-F3: Histopathological findings (hematoxylin-erosin staining, x20/x40). Small focus of adenocarcinoma in the gastric hyperplastic polyp, with a distinct mitotic figure (arrow).

Mentions: Histopathological evaluation of the largest hyperplastic polyp resected from the body of the stomach (Figure 2) revealed well-differentiated focal adenocarcinoma (Figure 3) with significant expression of p53 protein (Figure 4). The lesion did not extend beyond the muscularis mucosae, were completely removed endoscopically with an excision margin of greater than 2 mm, and no evidence of lymphovascular invasion was identified. Accordingly, mucosectomy was microscopically assessed as complete. The polyp with focal adenocarcinoma was classified as early stomach cancer, grade 0–Is (superficial, protruded, sessile) according to the Paris Classification of Superficial Gastrointestinal Neoplastic Lesions, and grade T1a by the TNM Classification of Malignant Tumours. Histopathological assessment of biopsy specimens, collected from the mucous membrane of the antrum and the body of the stomach, showed chronic gastritis as well as helicobacter pylori (H. pylori) infection; eradication therapy was prescribed.Figure 2.


Gastric hyperplastic polyp with focal cancer.

Markowski AR, Guzinska-Ustymowicz K - Gastroenterol Rep (Oxf) (2014)

Histopathological findings (hematoxylin-erosin staining, x20/x40). Small focus of adenocarcinoma in the gastric hyperplastic polyp, with a distinct mitotic figure (arrow).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4863182&req=5

gou077-F3: Histopathological findings (hematoxylin-erosin staining, x20/x40). Small focus of adenocarcinoma in the gastric hyperplastic polyp, with a distinct mitotic figure (arrow).
Mentions: Histopathological evaluation of the largest hyperplastic polyp resected from the body of the stomach (Figure 2) revealed well-differentiated focal adenocarcinoma (Figure 3) with significant expression of p53 protein (Figure 4). The lesion did not extend beyond the muscularis mucosae, were completely removed endoscopically with an excision margin of greater than 2 mm, and no evidence of lymphovascular invasion was identified. Accordingly, mucosectomy was microscopically assessed as complete. The polyp with focal adenocarcinoma was classified as early stomach cancer, grade 0–Is (superficial, protruded, sessile) according to the Paris Classification of Superficial Gastrointestinal Neoplastic Lesions, and grade T1a by the TNM Classification of Malignant Tumours. Histopathological assessment of biopsy specimens, collected from the mucous membrane of the antrum and the body of the stomach, showed chronic gastritis as well as helicobacter pylori (H. pylori) infection; eradication therapy was prescribed.Figure 2.

Bottom Line: The frequency of surveillance endoscopy should depend on the precise histopathological diagnosis and possibility of confirming the completeness of the endoscopic resection.If the completeness of the procedure is confirmed both macro- and microscopically, gastric resection does not have to be performed.A follow-up esophago-gastroduodenoscopy should be performed at 1 year and then at 3 years.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, Bialystok, Poland Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, Bialystok, Poland markowski@szpitalpck.pl.

No MeSH data available.


Related in: MedlinePlus