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Comparison of congenital coronary artery anomalies between Uyghur and Han: a multi-slice computed tomography study in Xinjiang, China.

Pan C, Azhati G, Xing Y, Wang Y, Liu W - Chin. Med. J. (2015)

Bottom Line: Nineteen kinds of CCAAs were found: (1) The overall incidence of CCAAs was 2.72% (203/7469) among all patients, 2.34% (111/4746) among Han patients whereas a significant higher 3.93% (76/1934) among Uyghur patients (χ2 = 12.780,P < 0.05); (2) the incidence of CCAAs among male patients was 2.48% (76/3069) in Han while 4.33% (56/1293) in Uyghur (χ2 = 10.663, P < 0.05); (3) the incidence of CCAAs on the left side was 1.07% (51/4746) among Han patients while 2.17% (42/934) among Uyghur patients (χ2 = 12.047, P < 0.05); (4) among these 19 kinds of CCAAs, there were significant differences of the incidence of the following kinds of CCAAs between Uyghur and Han: Left coronary artery (LCA) high location (χ2 = 8.320, P = 0.004), right coronary artery (RCA) originate from left coronary sinus (χ2 = 5.450, P = 0.020), and RCA originate from left Coronary sinus + LCA high location (P = 0.024).There exists some difference in CCAAs between Uyghur and Han ethnic groups.The CCAAs incidence of Uyghur is higher than that of Han, especially in male patients and on the left side; among all kinds of CCAAs, the incidence of LCA high location, RCA originate from left coronary sinus, RCA originate from left coronary sinus + LCA high locations of Uyghur is higher than Han.

View Article: PubMed Central - PubMed

Affiliation: Imaging Center, First Teaching Hospital of Xingjiang Medical University, Urumqi, Xinjiang 830054, China.

ABSTRACT

Background: The incidence of congenital coronary artery anomalies (CCAAs) is different between ethnic groups, but there is no report about Uyghur CCAAs because of the limitation of inspection methods. This study determined the prevalence of Uyghur CCAAs and analysis the difference of CCAAs between Uyghur and Han ethnic groups by the method of multi-slice computed tomography coronary angiography (MSCTCA).

Methods: Seven thousand four hundred and sixty-nine MSCTCA were analyzed for the CCAAs retroactively, 1934 were Uyghur patients while 4746 were Han patients. All the coronary artery images dates obtained by MSCTCA were evaluated for the CCAAs by two doctors.

Results: Nineteen kinds of CCAAs were found: (1) The overall incidence of CCAAs was 2.72% (203/7469) among all patients, 2.34% (111/4746) among Han patients whereas a significant higher 3.93% (76/1934) among Uyghur patients (χ2 = 12.780,P < 0.05); (2) the incidence of CCAAs among male patients was 2.48% (76/3069) in Han while 4.33% (56/1293) in Uyghur (χ2 = 10.663, P < 0.05); (3) the incidence of CCAAs on the left side was 1.07% (51/4746) among Han patients while 2.17% (42/934) among Uyghur patients (χ2 = 12.047, P < 0.05); (4) among these 19 kinds of CCAAs, there were significant differences of the incidence of the following kinds of CCAAs between Uyghur and Han: Left coronary artery (LCA) high location (χ2 = 8.320, P = 0.004), right coronary artery (RCA) originate from left coronary sinus (χ2 = 5.450, P = 0.020), and RCA originate from left Coronary sinus + LCA high location (P = 0.024).

Conclusions: There exists some difference in CCAAs between Uyghur and Han ethnic groups. The CCAAs incidence of Uyghur is higher than that of Han, especially in male patients and on the left side; among all kinds of CCAAs, the incidence of LCA high location, RCA originate from left coronary sinus, RCA originate from left coronary sinus + LCA high locations of Uyghur is higher than Han.

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Right coronary artery and left coronary artery origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing.
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Figure 2: Right coronary artery and left coronary artery origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing.

Mentions: We found nine cases of RCA + LCA high location, and they can divide into two group: One group is RCA and LCA origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing [Figure 2], we classified it to “benign” group; another group is RCA and LCA origin from the ascending aorta above the commissural or the left sinus of Valsalva together, RCA passed between the aorta and PA before reaching the right atrioventricular groove [Figure 3], ostial occlusion due to aortic expansion during exercise may result in myocardial ischemia, so we classified it to “potentially serious” group. In this research, one case of RCA + LCA high location in Uyghur and one case of RCA + LCA high locations in other ethnic groups are “potentially serious”, three of seven cases of RCA + LCA high locations in Han are “potentially serious”, and the other 4 cases are “benign”.


Comparison of congenital coronary artery anomalies between Uyghur and Han: a multi-slice computed tomography study in Xinjiang, China.

Pan C, Azhati G, Xing Y, Wang Y, Liu W - Chin. Med. J. (2015)

Right coronary artery and left coronary artery origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4837813&req=5

Figure 2: Right coronary artery and left coronary artery origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing.
Mentions: We found nine cases of RCA + LCA high location, and they can divide into two group: One group is RCA and LCA origin from the ascending aorta above the sinuses of Valsalva separately without abnormal distributing [Figure 2], we classified it to “benign” group; another group is RCA and LCA origin from the ascending aorta above the commissural or the left sinus of Valsalva together, RCA passed between the aorta and PA before reaching the right atrioventricular groove [Figure 3], ostial occlusion due to aortic expansion during exercise may result in myocardial ischemia, so we classified it to “potentially serious” group. In this research, one case of RCA + LCA high location in Uyghur and one case of RCA + LCA high locations in other ethnic groups are “potentially serious”, three of seven cases of RCA + LCA high locations in Han are “potentially serious”, and the other 4 cases are “benign”.

Bottom Line: Nineteen kinds of CCAAs were found: (1) The overall incidence of CCAAs was 2.72% (203/7469) among all patients, 2.34% (111/4746) among Han patients whereas a significant higher 3.93% (76/1934) among Uyghur patients (χ2 = 12.780,P < 0.05); (2) the incidence of CCAAs among male patients was 2.48% (76/3069) in Han while 4.33% (56/1293) in Uyghur (χ2 = 10.663, P < 0.05); (3) the incidence of CCAAs on the left side was 1.07% (51/4746) among Han patients while 2.17% (42/934) among Uyghur patients (χ2 = 12.047, P < 0.05); (4) among these 19 kinds of CCAAs, there were significant differences of the incidence of the following kinds of CCAAs between Uyghur and Han: Left coronary artery (LCA) high location (χ2 = 8.320, P = 0.004), right coronary artery (RCA) originate from left coronary sinus (χ2 = 5.450, P = 0.020), and RCA originate from left Coronary sinus + LCA high location (P = 0.024).There exists some difference in CCAAs between Uyghur and Han ethnic groups.The CCAAs incidence of Uyghur is higher than that of Han, especially in male patients and on the left side; among all kinds of CCAAs, the incidence of LCA high location, RCA originate from left coronary sinus, RCA originate from left coronary sinus + LCA high locations of Uyghur is higher than Han.

View Article: PubMed Central - PubMed

Affiliation: Imaging Center, First Teaching Hospital of Xingjiang Medical University, Urumqi, Xinjiang 830054, China.

ABSTRACT

Background: The incidence of congenital coronary artery anomalies (CCAAs) is different between ethnic groups, but there is no report about Uyghur CCAAs because of the limitation of inspection methods. This study determined the prevalence of Uyghur CCAAs and analysis the difference of CCAAs between Uyghur and Han ethnic groups by the method of multi-slice computed tomography coronary angiography (MSCTCA).

Methods: Seven thousand four hundred and sixty-nine MSCTCA were analyzed for the CCAAs retroactively, 1934 were Uyghur patients while 4746 were Han patients. All the coronary artery images dates obtained by MSCTCA were evaluated for the CCAAs by two doctors.

Results: Nineteen kinds of CCAAs were found: (1) The overall incidence of CCAAs was 2.72% (203/7469) among all patients, 2.34% (111/4746) among Han patients whereas a significant higher 3.93% (76/1934) among Uyghur patients (χ2 = 12.780,P < 0.05); (2) the incidence of CCAAs among male patients was 2.48% (76/3069) in Han while 4.33% (56/1293) in Uyghur (χ2 = 10.663, P < 0.05); (3) the incidence of CCAAs on the left side was 1.07% (51/4746) among Han patients while 2.17% (42/934) among Uyghur patients (χ2 = 12.047, P < 0.05); (4) among these 19 kinds of CCAAs, there were significant differences of the incidence of the following kinds of CCAAs between Uyghur and Han: Left coronary artery (LCA) high location (χ2 = 8.320, P = 0.004), right coronary artery (RCA) originate from left coronary sinus (χ2 = 5.450, P = 0.020), and RCA originate from left Coronary sinus + LCA high location (P = 0.024).

Conclusions: There exists some difference in CCAAs between Uyghur and Han ethnic groups. The CCAAs incidence of Uyghur is higher than that of Han, especially in male patients and on the left side; among all kinds of CCAAs, the incidence of LCA high location, RCA originate from left coronary sinus, RCA originate from left coronary sinus + LCA high locations of Uyghur is higher than Han.

Show MeSH
Related in: MedlinePlus