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Early changes in right ventricular longitudinal function in chronic asymptomatic alcoholics revealed by two-dimensional speckle tracking echocardiography.

Meng S, Guo L, Li G - Cardiovasc Ultrasound (2016)

Bottom Line: Heart ventricular dysfunction has been characterized as reduced longitudinal function of the right ventricle (RV), and is associated with chronic alcohol abuse.In Group C, the RV end diastolic diameter (RVEDD) was dramatically higher than that of Groups A, B and the control, while TAPSE was significantly lower in Group C compared with the other experimental groups.In Group C, all the 2DSTE parameters were significantly lower than that of the other groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, China.

ABSTRACT

Background: Heart ventricular dysfunction has been characterized as reduced longitudinal function of the right ventricle (RV), and is associated with chronic alcohol abuse. This study investigated the use of two-dimensional speckle tracking echocardiography (2DSTE) to assess the longitudinal systolic and diastolic RV function of patients with alcoholic myocardial damage.

Methods: We stratified 92 asymptomatic alcoholic men into three groups of increasing alcohol intake, Groups A-C. Thirty age-matched normal adult men served as the control group. Conventional echocardiography and tricuspid annulus peak systolic excursion (TAPSE) parameters were obtained. 2DSTE parameters were recorded from an apical 4-chamber view of the RV free wall. LV peak global longitudinal systolic strain was calculated from segmental averaging of the three apical long-axis views.

Results: In Group C, the RV end diastolic diameter (RVEDD) was dramatically higher than that of Groups A, B and the control, while TAPSE was significantly lower in Group C compared with the other experimental groups. In Group B, the longitudinal early diastolic strain rate (SRe) and late diastolic strain rate (SRa) of the RV free wall, and LV longitudinal strain were significantly lower than that of Group A or the control. In Group C, all the 2DSTE parameters were significantly lower than that of the other groups. A significant negative linear correlation was noted between global RV systolic parameters systolic strain peak (S), peak systolic strain rate (SRs) and TAPSE (r1=-0.84, r2=-0.72, respectively, P <0.05).

Conclusions: Two-dimensional STE provided an effective and non-invasive method to assess the RV longitudinal function of patients with alcoholic myocardial damage. This methodology may be useful for diagnosing, directing treatment, and judging prognosis of alcoholic cardiac damage.

No MeSH data available.


Related in: MedlinePlus

Right ventricular peak systolic longitudinal strain of Group C
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Fig4: Right ventricular peak systolic longitudinal strain of Group C

Mentions: The LV longitudinal strain was less in Group B and C compared with both Group A and the control (Table 3). The average longitudinal strain and strain rate of each segment in the basal, mid, and apical regions of the RV free wall were determined in each group (Table 4). All measured echocardiographic variables in Group A were similar to that of the control group (P >0.05). The SRe and SRa of each RV free wall segment were significantly lower in Group B than in either Group A or the control group (P <0.05). However, the parameters P, S, and SRs of Groups A, B, and the control group were similar (P >0.05). Notably, all the diastolic parameters and the systolic parameters P, S, and SRs were significantly lower in Group C than in the other groups (P <0.05, all). Changes in myocardial strain within each segment (basal, mid, and apical) between the four groups are presented in Figs. 1, 2, 3 and 4.Table 3


Early changes in right ventricular longitudinal function in chronic asymptomatic alcoholics revealed by two-dimensional speckle tracking echocardiography.

Meng S, Guo L, Li G - Cardiovasc Ultrasound (2016)

Right ventricular peak systolic longitudinal strain of Group C
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4837624&req=5

Fig4: Right ventricular peak systolic longitudinal strain of Group C
Mentions: The LV longitudinal strain was less in Group B and C compared with both Group A and the control (Table 3). The average longitudinal strain and strain rate of each segment in the basal, mid, and apical regions of the RV free wall were determined in each group (Table 4). All measured echocardiographic variables in Group A were similar to that of the control group (P >0.05). The SRe and SRa of each RV free wall segment were significantly lower in Group B than in either Group A or the control group (P <0.05). However, the parameters P, S, and SRs of Groups A, B, and the control group were similar (P >0.05). Notably, all the diastolic parameters and the systolic parameters P, S, and SRs were significantly lower in Group C than in the other groups (P <0.05, all). Changes in myocardial strain within each segment (basal, mid, and apical) between the four groups are presented in Figs. 1, 2, 3 and 4.Table 3

Bottom Line: Heart ventricular dysfunction has been characterized as reduced longitudinal function of the right ventricle (RV), and is associated with chronic alcohol abuse.In Group C, the RV end diastolic diameter (RVEDD) was dramatically higher than that of Groups A, B and the control, while TAPSE was significantly lower in Group C compared with the other experimental groups.In Group C, all the 2DSTE parameters were significantly lower than that of the other groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, China.

ABSTRACT

Background: Heart ventricular dysfunction has been characterized as reduced longitudinal function of the right ventricle (RV), and is associated with chronic alcohol abuse. This study investigated the use of two-dimensional speckle tracking echocardiography (2DSTE) to assess the longitudinal systolic and diastolic RV function of patients with alcoholic myocardial damage.

Methods: We stratified 92 asymptomatic alcoholic men into three groups of increasing alcohol intake, Groups A-C. Thirty age-matched normal adult men served as the control group. Conventional echocardiography and tricuspid annulus peak systolic excursion (TAPSE) parameters were obtained. 2DSTE parameters were recorded from an apical 4-chamber view of the RV free wall. LV peak global longitudinal systolic strain was calculated from segmental averaging of the three apical long-axis views.

Results: In Group C, the RV end diastolic diameter (RVEDD) was dramatically higher than that of Groups A, B and the control, while TAPSE was significantly lower in Group C compared with the other experimental groups. In Group B, the longitudinal early diastolic strain rate (SRe) and late diastolic strain rate (SRa) of the RV free wall, and LV longitudinal strain were significantly lower than that of Group A or the control. In Group C, all the 2DSTE parameters were significantly lower than that of the other groups. A significant negative linear correlation was noted between global RV systolic parameters systolic strain peak (S), peak systolic strain rate (SRs) and TAPSE (r1=-0.84, r2=-0.72, respectively, P <0.05).

Conclusions: Two-dimensional STE provided an effective and non-invasive method to assess the RV longitudinal function of patients with alcoholic myocardial damage. This methodology may be useful for diagnosing, directing treatment, and judging prognosis of alcoholic cardiac damage.

No MeSH data available.


Related in: MedlinePlus