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Discovery of Nuclear DNA-like RNA (dRNA, hnRNA) and Ribonucleoproteins Particles Containing hnRNA.

Georgiev GP - Acta Naturae (2016 Jan-Mar)

Bottom Line: Therefore, I was invited to represent Russia at the Symposium and deliver a speech on these topics.However, my visa had only been issued after the end of the Symposium, and, therefore, the presentation was delivered by my former colleague G.N.The transcript of the lecture is presented below.

View Article: PubMed Central - PubMed

Affiliation: Institute of Gene Biology, Russian Academy of Sciences, Vavilova Str., 34/5, Moscow, 119334, Russia.

ABSTRACT
On August 9-11, 2014, Cold Spring Harbor (USA) hosted a special symposium dedicated to the discovery of messenger or informational RNA and the main events in the subsequent studies of its synthesis, regulation of synthesis, maturation, and transport. The existence of mRNA in bacteria was first suggested in 1961 by Jacob and Monod, based on genetic studies [1]. The same year, Brenner et al. confirmed the hypothesis [2]. Our laboratory played a key role in the discovery of messenger RNA in eukaryotes, as well as in the discovery of the nuclear ribonucleoproteins that contain it and in the elucidation of their structural organization. Therefore, I was invited to represent Russia at the Symposium and deliver a speech on these topics. However, my visa had only been issued after the end of the Symposium, and, therefore, the presentation was delivered by my former colleague G.N. Yenikolopov, who works at Cold Spring Harbor Laboratory. The transcript of the lecture is presented below.

No MeSH data available.


Related in: MedlinePlus

The super-long-distance interaction in the genome. They are definedby the interaction of insulators and can lead to activation of a promoter by anenhancer. Removal of any one or two insulators prevents this interaction
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Figure 7: The super-long-distance interaction in the genome. They are definedby the interaction of insulators and can lead to activation of a promoter by anenhancer. Removal of any one or two insulators prevents this interaction

Mentions: Super-long-distance interactions have been discovered in the genome[23, 24].They can reach dozens of millions of base pairs and canoccur even between non-homologous chromosomes. They depend on the interactionbetween insulators and can lead to activation of a promoter by an enhancer.Removal of one of the insulators results in a complete loss of super-long-distanceinteraction, which manifests itself as inactivation of the associated transcription(Fig. 7).


Discovery of Nuclear DNA-like RNA (dRNA, hnRNA) and Ribonucleoproteins Particles Containing hnRNA.

Georgiev GP - Acta Naturae (2016 Jan-Mar)

The super-long-distance interaction in the genome. They are definedby the interaction of insulators and can lead to activation of a promoter by anenhancer. Removal of any one or two insulators prevents this interaction
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4837567&req=5

Figure 7: The super-long-distance interaction in the genome. They are definedby the interaction of insulators and can lead to activation of a promoter by anenhancer. Removal of any one or two insulators prevents this interaction
Mentions: Super-long-distance interactions have been discovered in the genome[23, 24].They can reach dozens of millions of base pairs and canoccur even between non-homologous chromosomes. They depend on the interactionbetween insulators and can lead to activation of a promoter by an enhancer.Removal of one of the insulators results in a complete loss of super-long-distanceinteraction, which manifests itself as inactivation of the associated transcription(Fig. 7).

Bottom Line: Therefore, I was invited to represent Russia at the Symposium and deliver a speech on these topics.However, my visa had only been issued after the end of the Symposium, and, therefore, the presentation was delivered by my former colleague G.N.The transcript of the lecture is presented below.

View Article: PubMed Central - PubMed

Affiliation: Institute of Gene Biology, Russian Academy of Sciences, Vavilova Str., 34/5, Moscow, 119334, Russia.

ABSTRACT
On August 9-11, 2014, Cold Spring Harbor (USA) hosted a special symposium dedicated to the discovery of messenger or informational RNA and the main events in the subsequent studies of its synthesis, regulation of synthesis, maturation, and transport. The existence of mRNA in bacteria was first suggested in 1961 by Jacob and Monod, based on genetic studies [1]. The same year, Brenner et al. confirmed the hypothesis [2]. Our laboratory played a key role in the discovery of messenger RNA in eukaryotes, as well as in the discovery of the nuclear ribonucleoproteins that contain it and in the elucidation of their structural organization. Therefore, I was invited to represent Russia at the Symposium and deliver a speech on these topics. However, my visa had only been issued after the end of the Symposium, and, therefore, the presentation was delivered by my former colleague G.N. Yenikolopov, who works at Cold Spring Harbor Laboratory. The transcript of the lecture is presented below.

No MeSH data available.


Related in: MedlinePlus